Výsledky vyhledávání - "Benno Müller"

Scavenging of Dickkopf-1 by macromer-based biomaterials covalently decorated with sulfated hyaluronan displays pro-osteogenic effects

Autor: F. Mitrach, Vera Hintze, Matthias Schnabelrauch, Juliane Salbach-Hirsch, Michael C. Hacker, Benno Müller, Mathis Gronbach, V. Lidzba, Lorenz C. Hofbauer, Stephanie Möller, Sandra Rother, Michaela Schulz-Siegmund

Publikováno v: Acta biomaterialia. 114

Dickkopf-1 (DKK1), a Wnt inhibitor secreted by bone marrow stromal cells (MSC), is known to play an important role in long-term non-union bone fracture defects and glucocorticoid induced osteoporosis. Mitigating its effects in early bone defects coul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::139c80c5d8812b5efcdfe364af3de125
https://pubmed.ncbi.nlm.nih.gov/32673749

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Surface modification of copolymerized films from three-armed biodegradable macromers – An analytical platform for modified tissue engineering scaffolds

Autor: Benno Müller, Friederike Zühl, Michael C. Hacker, Liv Kalbitzer, Peter-Georg Hoffmeister, Rudi Loth, Michaela Schulz-Siegmund

Publikováno v: Acta Biomaterialia. 51:148-160

The concept of macromers allows for a broad adjustment of biomaterial properties by macromer chemistry or copolymerization. Copolymerization strategies can also be used to introduce reactive sites for subsequent surface modification. Control over sur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57dabc61b859bad4936213808cfcb1ff
https://doi.org/10.1016/j.actbio.2017.01.018

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Temporary watertight connection of excavations to existing buildings and temporary waterproofing of structures by ground freezing / Temporäre wasserdichte Anbindung von Baugruben an Bestandsbauwerke und temporäres Abdichten von Bauwerken durch Baugrundver

Autor: Benno Müller, Wolfgang Orth

Publikováno v: Geomechanics and Tunnelling. 6:246-260

The ground freezing technique is used not only to stabilise soil but also for sealing excavations and tunnels below groundwater level. As it can be applied in various soil types and controlled very well by temperature measurement, it can be used as a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a8c7562bb1bbc6ccb3a3f9c75783a8a8
https://doi.org/10.1002/geot.201300015

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Baupraktische Erfahrungen eines Vortriebs im Schutz eines umhüllenden Frostkörpers am Beispiel des U-Bahnhofs Brandenburger Tor, Berlin

Autor: Franz Bayer, Benno Müller

Publikováno v: Geomechanik und Tunnelbau. 1:498-503

In unmittelbarer Nahe zum Brandenburger Tor in Berlin-Mitte wurde im Kreuzungsbereich Unter den Linden/Wilhelmstrase der U-Bahnhof Brandenburger Tor uberwiegend in bergmannischer Bauweise im Schutz einer Bodenvereisung erbaut. Die Arbeitsgemeinschaft

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::04dd246650cfde7dcb573a5601582930
https://doi.org/10.1002/geot.200800040

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Induction of the lac promoter in the absence of DNA loops and the stoichiometry of induction

Autor: Stefan Oehler, Siegfried Alberti, Benno Müller-Hill

Publikováno v: Nucleic Acids Research

In vivo induction of the Escherichia coli lactose operon as a function of inducer concentration generates a sigmoidal curve, indicating a non-linear response. Suggested explanations for this dependence include a 2:1 inducer-repressor stoichiometry of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43dcd5dc6b6d1c525fccda44a0be3bd4
http://europepmc.org/articles/PMC1345695

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Genetics of susceptibility to tuberculosis: Mengele's experiments in Auschwitz

Autor: Benno Müller-Hill

Publikováno v: Nature Reviews Genetics. 2:631-634

Great experiments will always be remembered. I highlight an experiment that was conducted during the Nazi regime in Germany. Not only did the experiment fail, it was also linked to fraud and crimes against humanity. This failed experiment will never

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53e3d8ddcb7b2c38ef85b13c1891bcf2
https://doi.org/10.1038/35084588

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Strengthening the dimerisation interface of lac repressor increases its thermostability by 40 deg. C 1 1Edited by M. Yaniv

Autor: Lily Pereg Gerk, Oliver Leven, Benno Müller-Hill

Publikováno v: Journal of Molecular Biology. 299:805-812

We increased drastically the heat stability of Lac repressor (LacR) of Escherichia coli. Wild-type tetrameric LacR denatures irreversibly at 53°C. Improving hydrophobic packing at the dimerisation interface by a single substitution increases LacR he

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ff4115edb6c6729e40570ab038d91e23
https://doi.org/10.1006/jmbi.2000.3706

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Dimerisation mutants of lac repressor. II. A single amino acid substitution, D278L, changes the specificity of dimerisation 1 1Edited by M. Yaniv

Autor: Fumin Dong, Brigitte Kisters-Woike, Benno Müller-Hill, Stefanie Spott

Publikováno v: Journal of Molecular Biology. 296:673-684

Assembly of the lactose repressor tetramer involves two subunit interfaces, the C-terminal heptad repeats, and the monomer-monomer interface. Dimerisation between two monomers of Lac repressor of Escherichia coli lacking the two C-terminal heptad rep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::194a59672cc94271e75e54f486d6d311
https://doi.org/10.1006/jmbi.1999.3469

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