Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Bennett G. Novitch"'
Autor:
Kristen M. Stearns-Reider, Michael R. Hicks, Katherine G. Hammond, Joseph C. Reynolds, Alok Maity, Yerbol Z. Kurmangaliyev, Jesse Chin, Adam Z. Stieg, Nicholas A. Geisse, Sophia Hohlbauch, Stefan Kaemmer, Lauren R. Schmitt, Thanh T. Pham, Ken Yamauchi, Bennett G. Novitch, Roy Wollman, Kirk C. Hansen, April D. Pyle, Rachelle H. Crosbie
Publikováno v:
npj Regenerative Medicine, Vol 8, Iss 1, Pp 1-22 (2023)
Abstract We developed an on-slide decellularization approach to generate acellular extracellular matrix (ECM) myoscaffolds that can be repopulated with various cell types to interrogate cell-ECM interactions. Using this platform, we investigated whet
Externí odkaz:
https://doaj.org/article/c2a5068dfc864da18363d4d91d1aaa4b
Autor:
Mariko Taniguchi-Ikeda, Michiyo Koyanagi-Aoi, Tatsuo Maruyama, Toru Takaori, Akiko Hosoya, Hiroyuki Tezuka, Shotaro Nagase, Takuma Ishihara, Taisuke Kadoshima, Keiko Muguruma, Keiko Ishigaki, Hidetoshi Sakurai, Akira Mizoguchi, Bennett G. Novitch, Tatsushi Toda, Momoko Watanabe, Takashi Aoi
Publikováno v:
iScience, Vol 24, Iss 10, Pp 103140- (2021)
Summary: Fukuyama congenital muscular dystrophy (FCMD) is a severe, intractable genetic disease that affects the skeletal muscle, eyes, and brain and is attributed to a defect in alpha dystroglycan (αDG) O-mannosyl glycosylation. We previously estab
Externí odkaz:
https://doaj.org/article/9e0187a4344d489cb9ee7920e4ea9915
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100319- (2021)
Summary: We describe two differentiation protocols to derive sensory spinal interneurons (INs) from human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs). In protocol 1, we use retinoic acid (RA) to induce pain, itch, and heat
Externí odkaz:
https://doaj.org/article/5a8af3a6849e4d6f97e5fca5e59a1e26
Autor:
Caroline Alayne Pearson, Destaye M. Moore, Haley O. Tucker, Joseph D. Dekker, Hui Hu, Amaya Miquelajáuregui, Bennett G. Novitch
Publikováno v:
Cell Reports, Vol 30, Iss 6, Pp 1964-1981.e3 (2020)
Summary: The laminar architecture of the mammalian neocortex depends on the orderly generation of distinct neuronal subtypes by apical radial glia (aRG) during embryogenesis. Here, we identify critical roles for the autism risk gene Foxp1 in maintain
Externí odkaz:
https://doaj.org/article/2bb491ebc4e24fe5ba78d5df2fae100a
Autor:
Momoko Watanabe, Jessie E. Buth, Neda Vishlaghi, Luis de la Torre-Ubieta, Jiannis Taxidis, Baljit S. Khakh, Giovanni Coppola, Caroline A. Pearson, Ken Yamauchi, Danyang Gong, Xinghong Dai, Robert Damoiseaux, Roghiyh Aliyari, Simone Liebscher, Katja Schenke-Layland, Christine Caneda, Eric J. Huang, Ye Zhang, Genhong Cheng, Daniel H. Geschwind, Peyman Golshani, Ren Sun, Bennett G. Novitch
Publikováno v:
Cell Reports, Vol 21, Iss 2, Pp 517-532 (2017)
Summary: The human cerebral cortex possesses distinct structural and functional features that are not found in the lower species traditionally used to model brain development and disease. Accordingly, considerable attention has been placed on the dev
Externí odkaz:
https://doaj.org/article/f6d8829ae13a41c591ef2cc136db7da7
Autor:
Pawel Niewiadomski, Jennifer H. Kong, Robert Ahrends, Yan Ma, Eric W. Humke, Sohini Khan, Mary N. Teruel, Bennett G. Novitch, Rajat Rohatgi
Publikováno v:
Cell Reports, Vol 6, Iss 1, Pp 168-181 (2014)
Gli proteins are transcriptional effectors of the Hedgehog (Hh) pathway in both normal development and cancer. We describe a program of multisite phosphorylation that regulates the conversion of Gli proteins into transcriptional activators. In the ab
Externí odkaz:
https://doaj.org/article/6a63a339a9c3497cb6b345fdd65039d4
Autor:
Jiwen Li, Marlesa I. Godoy, Alice J. Zhang, Graciel Diamante, In Sook Ahn, Arantxa Cebrian-Silla, Arturo Alvarez-Buylla, Xia Yang, Bennett G. Novitch, Ye Zhang
Publikováno v:
bioRxiv
Embryonic neural stem cells (NSCs,i.e., radial glia) in the ventricular-subventricular zone (V-SVZ) generate the majority of neurons and glia in the forebrain. Postnatally, embryonic radial glia disappear and a subpopulation of radial glia transition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf20db26ebc0b156308af360913ac835
https://europepmc.org/articles/PMC9949035/
https://europepmc.org/articles/PMC9949035/
Autor:
Andrew J. Lund, Istvan Mody, John Huang, Inma Cobos, William E. Lowry, Marcos Otero-Garcia, Justin Langerman, Ranmal A. Samarasinghe, Kathrin Plath, Damon Polioudakis, Shan Sabri, Xiaofei Wei, Bennett G. Novitch, Daniel H. Geschwind, Thomas F. Allison
Publikováno v:
Stem cell reports, vol 16, iss 10
Stem Cell Reports
Stem Cell Reports
Summary The specification of inhibitory neurons has been described for the mouse and human brain, and many studies have shown that pluripotent stem cells (PSCs) can be used to create interneurons in vitro. It is unclear whether in vitro methods to pr
Autor:
Jiajia Wang, Lijun Yang, Mingqing Jiang, Chuntao Zhao, Xuezhao Liu, Kalen Berry, Ari Waisman, Abraham J. Langseth, Bennett G. Novitch, Dwight E. Bergles, Akiko Nishiyama, Q. Richard Lu
Publikováno v:
J Neurosci
The oligodendrocyte (OL) lineage transcription factor Olig2 is expressed throughout oligodendroglial development and is essential for oligodendroglial progenitor specification and differentiation. It was previously reported that deletion ofOlig2enhan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4616e648de671bd251411bbd1f2aac18
https://europepmc.org/articles/PMC9665935/
https://europepmc.org/articles/PMC9665935/
Autor:
Caroline A. Pearson, Jessie E. Buth, Michael R.M. Harrison, M. Elizabeth Ross, Bennett G. Novitch
Radial glia progenitors within the cerebral cortex undergo a characteristic switch between symmetric self-renewing cell divisions early in development and asymmetric neurogenic divisions at later times, yet the mechanisms controlling this transition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5779e7d284e50ae248b277915a6e9a0b
https://doi.org/10.1101/2022.10.17.512545
https://doi.org/10.1101/2022.10.17.512545