Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Bennett G Novitch"'
Autor:
Andreas Sagner, Zachary B Gaber, Julien Delile, Jennifer H Kong, David L Rousso, Caroline A Pearson, Steven E Weicksel, Manuela Melchionda, S Neda Mousavy Gharavy, James Briscoe, Bennett G Novitch
Publikováno v:
PLoS Biology, Vol 16, Iss 2, p e2003127 (2018)
During tissue development, multipotent progenitors differentiate into specific cell types in characteristic spatial and temporal patterns. We addressed the mechanism linking progenitor identity and differentiation rate in the neural tube, where motor
Externí odkaz:
https://doaj.org/article/84aadd8ec59747d7be20f2ba715fe14d
Autor:
Anthony J Linares, Chia-Ho Lin, Andrey Damianov, Katrina L Adams, Bennett G Novitch, Douglas L Black
Publikováno v:
eLife, Vol 4 (2015)
The RNA-binding proteins PTBP1 and PTBP2 control programs of alternative splicing during neuronal development. PTBP2 was found to maintain embryonic splicing patterns of many synaptic and cytoskeletal proteins during differentiation of neuronal proge
Externí odkaz:
https://doaj.org/article/6e06fcc18c114fd49ebf33b7f6580d31
Publikováno v:
PLoS Biology, Vol 11, Iss 10, p e1001676 (2013)
Distinct classes of neurons and glial cells in the developing spinal cord arise at specific times and in specific quantities from spatially discrete neural progenitor domains. Thus, adjacent domains can exhibit marked differences in their proliferati
Externí odkaz:
https://doaj.org/article/b57e6ea0918c482b9dc49f308dd650ae
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36049 (2012)
A key objective of stem cell biology is to create physiologically relevant cells suitable for modeling disease pathologies in vitro. Much progress towards this goal has been made in the area of motor neuron (MN) disease through the development of met
Externí odkaz:
https://doaj.org/article/25bf8d71cc134ced9b74f8fd1e4d1c17
Publikováno v:
PLoS Biology, Vol 9, Iss 2, p e1001020 (2011)
The initiation, execution, and completion of complex locomotor behaviors are depending on precisely integrated neural circuitries consisting of motor pathways that activate muscles in the extremities and sensory afferents that deliver feedback to mot
Externí odkaz:
https://doaj.org/article/22d67e3c21ca4409bbb3153d306c3d5a
Autor:
Elena Palmesino, David L Rousso, Tzu-Jen Kao, Avihu Klar, Ed Laufer, Osamu Uemura, Hitoshi Okamoto, Bennett G Novitch, Artur Kania
Publikováno v:
PLoS Biology, Vol 8, Iss 8, p e1000446 (2010)
Topographic neuronal maps arise as a consequence of axon trajectory choice correlated with the localisation of neuronal soma, but the identity of the pathways coordinating these processes is unknown. We addressed this question in the context of the m
Externí odkaz:
https://doaj.org/article/88a709e381b94966935852b8bb3bc3f3
Autor:
Eric Dessaud, Vanessa Ribes, Nikolaos Balaskas, Lin Lin Yang, Alessandra Pierani, Anna Kicheva, Bennett G Novitch, James Briscoe, Noriaki Sasai
Publikováno v:
PLoS Biology, Vol 8, Iss 6, p e1000382 (2010)
Morphogens are secreted signalling molecules that act in a graded manner to control the pattern of cellular differentiation in developing tissues. An example is Sonic hedgehog (Shh), which acts in several developing vertebrate tissues, including the
Externí odkaz:
https://doaj.org/article/2aff196356d5450b80e38bb51ec9e56e
Autor:
Kristen M. Stearns-Reider, Michael R. Hicks, Katherine G. Hammond, Joseph C. Reynolds, Alok Maity, Yerbol Z. Kurmangaliyev, Jesse Chin, Adam Z. Stieg, Nicholas A. Geisse, Sophia Hohlbauch, Stefan Kaemmer, Lauren R. Schmitt, Thanh T. Pham, Ken Yamauchi, Bennett G. Novitch, Roy Wollman, Kirk C. Hansen, April D. Pyle, Rachelle H. Crosbie
Publikováno v:
npj Regenerative Medicine, Vol 8, Iss 1, Pp 1-22 (2023)
Abstract We developed an on-slide decellularization approach to generate acellular extracellular matrix (ECM) myoscaffolds that can be repopulated with various cell types to interrogate cell-ECM interactions. Using this platform, we investigated whet
Externí odkaz:
https://doaj.org/article/c2a5068dfc864da18363d4d91d1aaa4b
Autor:
Jiwen Li, Marlesa I. Godoy, Alice J. Zhang, Graciel Diamante, In Sook Ahn, Arantxa Cebrian-Silla, Arturo Alvarez-Buylla, Xia Yang, Bennett G. Novitch, Ye Zhang
Publikováno v:
bioRxiv
Embryonic neural stem cells (NSCs,i.e., radial glia) in the ventricular-subventricular zone (V-SVZ) generate the majority of neurons and glia in the forebrain. Postnatally, embryonic radial glia disappear and a subpopulation of radial glia transition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf20db26ebc0b156308af360913ac835
https://europepmc.org/articles/PMC9949035/
https://europepmc.org/articles/PMC9949035/
Autor:
Andrew J. Lund, Istvan Mody, John Huang, Inma Cobos, William E. Lowry, Marcos Otero-Garcia, Justin Langerman, Ranmal A. Samarasinghe, Kathrin Plath, Damon Polioudakis, Shan Sabri, Xiaofei Wei, Bennett G. Novitch, Daniel H. Geschwind, Thomas F. Allison
Publikováno v:
Stem cell reports, vol 16, iss 10
Stem Cell Reports
Stem Cell Reports
Summary The specification of inhibitory neurons has been described for the mouse and human brain, and many studies have shown that pluripotent stem cells (PSCs) can be used to create interneurons in vitro. It is unclear whether in vitro methods to pr