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Update on biomarkers in neuromyelitis optica

Autor: Zamvil, Scott, Waubant, Emmanuelle, Melamed, E, Levy, M, Waters, PJ, Sato, DK, Bennett, JL, John, GR, Hooper, DC, Saiz, A, Bar-Or, A, Kim, HJ

Publikováno v: Zamvil, Scott; Waubant, Emmanuelle; Melamed, E; Levy, M; Waters, PJ; Sato, DK; et al.(2015). Update on biomarkers in neuromyelitis optica.. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/3v1718g9

Neuromyelitis optica (NMO) (and NMO spectrum disorder) is an autoimmune inflammatory disease of the CNS primarily affecting spinal cord and optic nerves. Reliable and sensitive biomarkers for onset, relapse, and progression in NMO are urgently needed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::186470b6ca9d82b374151b2a30601788
http://www.escholarship.org/uc/item/3v1718g9

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B lymphocytes in neuromyelitis optica

Autor: Zamvil, Scott, Yeaman, Michael, Von Buedingen, Hans-Christian, Bennett, JL, O'Connor, KC, Bar-Or, A, Zamvil, SS, Hemmer, B, Tedder, TF, von, H-C, Stuve, O, Yeaman, MR, Smith, TJ

Publikováno v: Zamvil, Scott; Yeaman, Michael; Von Buedingen, Hans-Christian; Bennett, JL; O'Connor, KC; Bar-Or, A; et al.(2015). B lymphocytes in neuromyelitis optica.. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/2mh587z8

Neuromyelitis optica (NMO) is an inflammatory autoimmune disorder of the CNS that predominantly affects the spinal cord and optic nerves. A majority (approximately 75%) of patients with NMO are seropositive for autoantibodies against the astrocyte wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::38a7ffbd225f82f87d51ded37a17eaf4
http://www.escholarship.org/uc/item/2mh587z8

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Mutagenesis of the aquaporin 4 extracellular domains defines restricted binding patterns of pathogenic neuromyelitis optica IgG

Autor: Verkman, Alan, Owens, GP, Ritchie, A, Rossi, A, Schaller, K, Wemlinger, S, Schumann, H, Shearer, A, Verkman, AS, Bennett, JL

Publikováno v: Verkman, Alan; Owens, GP; Ritchie, A; Rossi, A; Schaller, K; Wemlinger, S; et al.(2015). Mutagenesis of the aquaporin 4 extracellular domains defines restricted binding patterns of pathogenic neuromyelitis optica IgG. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/1dg0c7k6

© 2015 by The American Society for Biochemistry and Molecular Biology, Inc.Neuromyelitis optica-immunoglobulin G (NMO-IgG) binds to aquaporin-4 (AQP4) water channels in the central nervous system leading to immune-mediated injury. We have previously

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::d4f57f8ee1809b67a66ae952829f3eb4
http://www.escholarship.org/uc/item/1dg0c7k6

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Neuromyelitis optica and multiple sclerosis: Seeing differences through optical coherence tomography

Autor: Green, Ari, Bennett, JL, de, J, Lana-Peixoto, M, Palace, J, Waldman, A, Schippling, S, Tenembaum, S, Banwell, B, Greenberg, B, Levy, M

Publikováno v: Green, Ari; Bennett, JL; de, J; Lana-Peixoto, M; Palace, J; Waldman, A; et al.(2015). Neuromyelitis optica and multiple sclerosis: Seeing differences through optical coherence tomography. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/6db4s9n5

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::ad799201a6d09dae4c72b4e028eda7b9
http://www.escholarship.org/uc/item/6db4s9n5

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Experimental mouse model of optic neuritis with inflammatory demyelination produced by passive transfer of neuromyelitis optica-immunoglobulin G

Autor: Verkman, Alan, Asavapanumas, N, Ratelade, J, Papadopoulos, MC, Bennett, JL, Levin, MH, Verkman, AS

Publikováno v: Verkman, Alan; Asavapanumas, N; Ratelade, J; Papadopoulos, MC; Bennett, JL; Levin, MH; et al.(2014). Experimental mouse model of optic neuritis with inflammatory demyelination produced by passive transfer of neuromyelitis optica-immunoglobulin G. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/7jh8b7p4

Background: Although optic neuritis (ON) is a defining feature of neuromyelitis optica (NMO), appropriate animal models of NMO ON are lacking. Most NMO patients are seropositive for immunoglobulin G autoantibodies (NMO-IgG) against the astrocyte wate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::5c6ceb16d0c8061902e704afca34e3b3
http://www.escholarship.org/uc/item/7jh8b7p4

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A consensus protocol for the standardisation of cerebrospinal fluid collection and biobanking

Publikováno v: Teunissen, C E, Petzold, A F S, Bennett, J L, Berven, F S, Brundin, L, Comabella, M, Franciotta, D, Federiksen, J L, Fleming, J O, Furlan, R, Hintzen, R Q, Hughes, S G, Johnson, M H, Krasulova, E, Kuhle, J, Magnone, M C, Rajda, C, Rejdak, K, Schmidt, H K, van Pesch, V, Waubant, E, Wolf, C, Giovannoni, G, Deisenhammer, F, Hegen, H, Hemmer, B & Tumani, H T 2010, ' A consensus protocol for the standardisation of cerebrospinal fluid collection and biobanking ', Laboratoriumsmedizin, vol. 34, no. 1, pp. 1-12 . https://doi.org/10.1515/JLM.2010.001
Laboratoriumsmedizin, 34(1), 1-12
Laboratoriumsmedizin-Journal of laboratory medicine, 34(1), 1-12. De Gruyter

There is a long history of research on body fluid biomarkers in neurodegenerative and neuroinflammatory diseases. However, only very few biomarkers in cerebrospinal fluid (CSF) are being used in clinical practice. One of the most critical factors in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::145d5b38c1aed7eee96c27df399196f4
https://research.vumc.nl/en/publications/b667421c-5143-417f-b86d-2d6c78d88f9f

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