Prodrugs of PKC modulators show enhanced HIV latency reversal and an expanded therapeutic window.

Autor: Sloane JL; Department of Chemistry, Stanford University, Stanford, CA 94305., Benner NL; Department of Chemistry, Stanford University, Stanford, CA 94305., Keenan KN; Department of Chemistry, Stanford University, Stanford, CA 94305., Zang X; Department of Chemistry, Stanford University, Stanford, CA 94305., Soliman MSA; Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA 90095., Wu X; Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA 90095., Dimapasoc M; Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA 90095.; Molecular Biology Institute, University of California, Los Angeles, CA 90095., Chun TW; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892., Marsden MD; Department of Medicine, Division of Hematology and Oncology, University of California, Los Angeles, CA 90095; mmarsden@ucla.edu jzack@ucla.edu wenderp@stanford.edu., Zack JA; Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA 90095; mmarsden@ucla.edu jzack@ucla.edu wenderp@stanford.edu.; Department of Medicine, Division of Hematology and Oncology, University of California, Los Angeles, CA 90095., Wender PA; Department of Chemistry, Stanford University, Stanford, CA 94305; mmarsden@ucla.edu jzack@ucla.edu wenderp@stanford.edu.; Department of Chemical and Systems Biology, Stanford University, Stanford, CA 94305.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 May 19; Vol. 117 (20), pp. 10688-10698. Date of Electronic Publication: 2020 May 05.

Oligo(serine ester) Charge-Altering Releasable Transporters: Organocatalytic Ring-Opening Polymerization and their Use for in Vitro and in Vivo mRNA Delivery.

Autor: Benner NL; Department of Chemistry , Stanford University , Stanford , California 94305 , United States., McClellan RL; Department of Chemistry , Stanford University , Stanford , California 94305 , United States., Turlington CR; Department of Chemistry , Stanford University , Stanford , California 94305 , United States., Haabeth OAW; Department of Medicine, Division of Oncology, Stanford Cancer Institute , Stanford University , Stanford , California 94305 , United States., Waymouth RM; Department of Chemistry , Stanford University , Stanford , California 94305 , United States., Wender PA; Department of Chemistry , Stanford University , Stanford , California 94305 , United States.; Department of Chemical and Systems Biology , Stanford University , Stanford , California 94305 , United States.

Publikováno v: Journal of the American Chemical Society [J Am Chem Soc] 2019 May 29; Vol. 141 (21), pp. 8416-8421. Date of Electronic Publication: 2019 May 17.

Enhanced mRNA delivery into lymphocytes enabled by lipid-varied libraries of charge-altering releasable transporters.

Autor: McKinlay CJ; Department of Chemistry, Stanford University, Stanford, CA 94305., Benner NL; Department of Chemistry, Stanford University, Stanford, CA 94305., Haabeth OA; Division of Oncology, Department of Medicine, Stanford Cancer Institute, Stanford University, Stanford, CA 94305., Waymouth RM; Department of Chemistry, Stanford University, Stanford, CA 94305; waymouth@stanford.edu wenderp@stanford.edu., Wender PA; Department of Chemistry, Stanford University, Stanford, CA 94305; waymouth@stanford.edu wenderp@stanford.edu.; Department of Chemical and Systems Biology, Stanford University, Stanford, CA 94305.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2018 Jun 26; Vol. 115 (26), pp. E5859-E5866. Date of Electronic Publication: 2018 Jun 11.

Vault Nanoparticles: Chemical Modifications for Imaging and Enhanced Delivery.

Autor: Benner NL, Zang X, Buehler DC, Kickhoefer VA; Department of Biological Chemistry, David Geffen School of Medicine at University of California Los Angeles , Los Angeles, California 90095, United States., Rome ME; Department of Biological Chemistry, David Geffen School of Medicine at University of California Los Angeles , Los Angeles, California 90095, United States., Rome LH; Department of Biological Chemistry, David Geffen School of Medicine at University of California Los Angeles , Los Angeles, California 90095, United States., Wender PA

Publikováno v: ACS nano [ACS Nano] 2017 Jan 24; Vol. 11 (1), pp. 872-881. Date of Electronic Publication: 2017 Jan 03.

Automated microarray platform for single‐cell sorting and collection of lymphocytes following HIV reactivation.

Autor: Cortés‐Llanos, Belén^1,2 (AUTHOR), Jain, Vaibhav³ (AUTHOR), Cooper‐Volkheimer, Alicia² (AUTHOR), Browne, Edward P.^4,5,6 (AUTHOR), Murdoch, David M.² (AUTHOR) david.murdoch@duke.edu, Allbritton, Nancy L.¹ (AUTHOR) nlallbr@uw.edu

Publikováno v: Bioengineering & Translational Medicine. Sep2023, Vol. 8 Issue 5, p1-15. 15p.