Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Benjamin Wiench"'
Autor:
Victor Kuete, Hippolyte K Wabo, Kenneth O Eyong, Michel T Feussi, Benjamin Wiench, Benjamin Krusche, Pierre Tane, Gabriel N Folefoc, Thomas Efferth
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e21762 (2011)
BACKGROUND: Natural products are well recognized as sources of drugs in several human ailments. In the present work, we carried out a preliminary screening of six natural compounds, xanthone V(1) (1); 2-acetylfuro-1,4-naphthoquinone (2); physcion (3)
Externí odkaz:
https://doaj.org/article/3e2e4ed48d0943a4996464f51e9c479d
Autor:
Meng Luo, Zuo-Fu Wei, Yu-Jie Fu, Cheng-Bo Gu, Xiaohe Yang, Wei Wang, Thomas Efferth, Onat Kadioglu, Benjamin Wiench, Yuangang Zu
Publikováno v:
The Journal of Nutritional Biochemistry. 26:1273-1282
Antiestrogenic therapy is a mainstay for estrogen receptor (ERα)-positive breast cancer. Due to the development of resistance to established antihormones such as tamoxifen, novel compounds are required. The low abundant cajanin stilbene acid (CSA) r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a6819f93ffafa7cd8bf4d09bc55a5e1
https://doi.org/10.1016/j.jnutbio.2015.06.004
https://doi.org/10.1016/j.jnutbio.2015.06.004
Autor:
Augustin Ephrem Nkengfack, Victor Kuete, Thomas Efferth, Armelle T. Mbaveng, Benjamin Wiench, Hugues Fouotsa
Publikováno v:
Phytomedicine. 22:946-951
Introduction Chemotherapy is one of the preferred mode of treatment of malignancies, but is complicated by the expression of diverse resistance mechanisms of cancer cells. Methods In the present study, we investigated the cytotoxicity of five alkaloi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7968bb38e01340415c436ae9ab3bd8cc
https://doi.org/10.1016/j.phymed.2015.07.002
https://doi.org/10.1016/j.phymed.2015.07.002
Autor:
Yuangang Zu, Malte Paulsen, Thomas Efferth, Ean-Jeong Seo, Benjamin Wiench, Rebecca Hamm, Yu-Jie Fu
Publikováno v:
Phytomedicine. 22:438-443
Although cancer stem-like cells (CSCs) are rare, they can enter a non-proliferative or dormant state and resist therapy. Furthermore, quiescent CSCs are responsible for metastases that can appear after curative surgical treatment of a primary tumor.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04ea83b973d199e32994d8b2b24947a2
https://doi.org/10.1016/j.phymed.2015.01.012
https://doi.org/10.1016/j.phymed.2015.01.012
Autor:
Yuangang Zu, Meng Luo, Yu-Jie Fu, Zuo-Fu Wei, Benjamin Wiench, Chang Gao, Cheng-Bo Gu, Onat Kadioglu, Thomas Efferth
Publikováno v:
Phytomedicine. 22:462-468
Background: The low abundant cajanin stilbene acid (CSA) from Pigeon Pea ( Cajanus cajan ) has been shown to kill estrogen receptor α positive cancer cells in vitro and in vivo . Downstream effects such as cell cycle and apoptosis-related mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ff88e5d69994fb4e5402032b95d6bb9
https://doi.org/10.1016/j.phymed.2015.02.005
https://doi.org/10.1016/j.phymed.2015.02.005
Publikováno v:
Archives of Toxicology. 90:575-588
In the present study, we investigated the activity and modes of action of cajanin stilbene acid (CSA) and its derivatives in terms of cytotoxicity, gene expression profile, and transcription factor activity. XTT assays on MCF7 cells were performed up
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bcab51f47786ce0506040e8376b1e05
https://doi.org/10.1007/s00204-015-1480-2
https://doi.org/10.1007/s00204-015-1480-2
Autor:
Simplice B. Tankeo, Pierre Tane, Mohamed E.M. Saeed, Thomas Efferth, Victor Kuete, Benjamin Wiench
Publikováno v:
Journal of Ethnopharmacology. 153:207-219
Ethnopharmacological relevance Beilschmiedia acuta Kosterm, Clausena anisata (Willd) Hook, Fagara tessmannii Engl., Newbouldia laevis Seem., and Polyscias fulva (Hiern) Harms. are medicinal plants used in Cameroonian traditional medicine in the treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d9cbf75edc3693c66ae8889b6c7910
https://doi.org/10.1016/j.jep.2014.02.025
https://doi.org/10.1016/j.jep.2014.02.025
Autor:
Benjamin Wiench, Guy M.N. Kwamou, Victor Kuete, Louis P. Sandjo, Augustin Ephrem Nkengfack, Thomas Efferth
Publikováno v:
Phytomedicine. 21:682-688
Introduction Resistance of cancer cells to chemotherapy has become a worldwide concern. Naturally occuring isoflavonoids possess a variety of biological activities including anti-cancer effects. The present study was aimed at investigating the cytoto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c4ca5b6729ca6587af7d37bab5d619
https://doi.org/10.1016/j.phymed.2013.10.017
https://doi.org/10.1016/j.phymed.2013.10.017
Autor:
Judith L. Nantchouang Ouete, Hugues Fouotsa, Benjamin Wiench, Victor Kuete, Louis P. Sandjo, Thomas Efferth
Publikováno v:
Phytomedicine. 21:315-322
Background Resistance of cancer to chemotherapy remains a challenging issue for scientists as well as physicians. Naturally occurring xanthones possess a variety of biological activities such as anti-inflammatory, anti-bacterial, and anti-cancer effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9873fbaecd49fb8157fe0f16f0dce21
https://doi.org/10.1016/j.phymed.2013.08.018
https://doi.org/10.1016/j.phymed.2013.08.018
Autor:
Patricia D. Tchakam, Thomas Efferth, Hippolyte K. Wabo, Victor Kuete, Bonaventure T. Ngadjui, Marlyse L. Moungang, Benjamin Wiench, Tetsuya Murayama, Michel F. Tala, Bathelemy Ngameni
Publikováno v:
Phytomedicine. 20:528-536
Introduction The emergence of drug-resistant cancer cells drastically reduces the efficacy of many antineoplasic agents and, consequently, increases the frequency of therapeutic failure. Benzophenones are known to display many pharmacological propert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0af3d1b7693b7e14252fa0925344d18
https://doi.org/10.1016/j.phymed.2013.02.003
https://doi.org/10.1016/j.phymed.2013.02.003