Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Benjamin T. Simms"'
Autor:
Michael Cappello, Benjamin T. Simms, Lisa M. Harrison, Jon J. Vermeire, Dylan Davey, Nisha Manickam
Publikováno v:
Experimental Parasitology. 133:243-249
Hookworms are bloodfeeding intestinal nematodes that are a major cause of anemia in resource-limited countries. Despite repeated exposure beginning in early childhood, humans retain lifelong susceptibility to infection without evidence of sterilizing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20762ce9fab7f936f464cffcbf3c7fe3
https://doi.org/10.1016/j.exppara.2012.11.010
https://doi.org/10.1016/j.exppara.2012.11.010
Alveolar Epithelial STAT3, IL-6 Family Cytokines, and Host Defense during Escherichia coli Pneumonia
Autor:
Joseph P. Mizgerd, Lee J. Quinton, Bryanne E. Robson, Matthew R. Jones, Benjamin T. Simms, Jeffrey A. Whitsett
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 38:699-706
While signal transducer and activator of transcription (STAT) 3 signaling has been linked to multiple pathways influencing immune function and cell survival, the direct influence of this transcription factor on innate immunity and tissue homeostasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86e0e7b0ef4376bea21c2f07562bd7da
https://doi.org/10.1165/rcmb.2007-0365oc
https://doi.org/10.1165/rcmb.2007-0365oc
Autor:
Joseph P. Mizgerd, Hongbo R. Luo, Hidenori Hattori, Benjamin T. Simms, Kulandayan K. Subramanian, Jian You, Yonghui Jia, Hakryul Jo, Daocheng Zhu
Publikováno v:
Blood. 109:4028-4037
The recruitment and activation of neutrophils at infected tissues is essential for host defense against invading microorganisms. However, excessive neutrophil recruitment or activation can also damage the surrounding tissues and cause unwanted inflam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d04f69f9ee7a8d86a38ce04ce5ff994f
https://doi.org/10.1182/blood-2006-10-055319
https://doi.org/10.1182/blood-2006-10-055319
Autor:
Peter Carmeliet, William C. Aird, Natalya Bodyak, Kiichiro Yano, Peter M. Kang, S. Ananth Karumanchi, Joseph P. Mizgerd, Bryan Belikoff, Hitomi Okada, Janet Mullington, Patricia C. Liaw, Benjamin T. Simms, Shu-Ching Shih, Jon A. Buras, Lisa J. Toltl
Publikováno v:
The Journal of Experimental Medicine
Sepsis, the systemic inflammatory response to infection, is a leading cause of morbidity and mortality. The mechanisms of sepsis pathophysiology remain obscure but are likely to involve a complex interplay between mediators of the inflammatory and co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c7704eedca6612da17eda1e0b41180f
https://doi.org/10.1084/jem.20060375
https://doi.org/10.1084/jem.20060375
Autor:
Benjamin T. Simms, Matthew R. Jones, Joseph P. Mizgerd, Lee J. Quinton, Mariya S. Kogan, Michal M. Lupa
Publikováno v:
The Journal of Infectious Diseases. 193:360-369
Interleukin (IL)-6 concentrations are positively associated with the severity of pneumonia, and this cytokine is essential to surviving experimental pneumococcal pneumonia. The role that IL-6 plays during pneumonia and its impact during gram-negative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1a95713dff47f3f4f055555c6533b82
https://doi.org/10.1086/499312
https://doi.org/10.1086/499312
Autor:
Debbie Humphries, Lisa M. Harrison, Dylan Davey, Josephine E. Quagraine, Sam Newton, Benjamin T. Simms, Michael R. Wilson, Elyssa Berg, Michael Cappello, Shawn Terryah, Daniel A. Boakye, Joseph Otchere
Children (n = 812) 6–11 years of age attending 16 schools in the Kintampo North Municipality of Ghana were screened for participation in a study on hookworm infection, nutrition, and response to albendazole. The prevalence of Necator americanus hoo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58e2e667666f195c3cccca6c889e9652
Autor:
Michael R. Wilson, Elyssa Berg, Dylan Davey, Lisa M. Harrison, Josephine E. Quagraine, Sam Newton, Joseph Otchere, Michael Cappello, Benjamin T. Simms, Daniel A. Boakye, Debbie Humphries
Publikováno v:
The FASEB Journal. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fa4f167179f3d8da109eea2bffbe151
https://doi.org/10.1096/fasebj.26.1_supplement.1028.6
https://doi.org/10.1096/fasebj.26.1_supplement.1028.6
Autor:
Shawn J. Skerrett, Matthew R. Jones, Mariya S. Kogan, Benjamin T. Simms, Joseph P. Mizgerd, Lee J. Quinton, Bryanne E. Robson
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 178(3)
Eradication of bacteria in the lower respiratory tract depends on the coordinated expression of proinflammatory cytokines and consequent neutrophilic inflammation. To determine the roles of the NF-κB subunit RelA in facilitating these events, we inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c1e580f902c389a0a3aec51faa6f96b
https://pubmed.ncbi.nlm.nih.gov/17237440
https://pubmed.ncbi.nlm.nih.gov/17237440
Autor:
Matthew R. Jones, Joseph P. Mizgerd, Alexander R. Ivanov, Benjamin T. Simms, Mariya S. Kogan, Dieter A. Wolf, Lee J. Quinton
Publikováno v:
The FASEB Journal. 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::452f261e0a1c9b4e0798618769b092c3
https://doi.org/10.1096/fasebj.20.5.a1443-a
https://doi.org/10.1096/fasebj.20.5.a1443-a
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 175(11)
Pulmonary inflammation is an essential component of the host defense against Streptococcus pneumoniae infection of the lungs. The early response cytokines, TNF-α and IL-1, are rapidly induced upon microbial exposure. Mice deficient in all TNF- and I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c44d8ffbe8f0d0af6dd9b381c121c9ef
https://pubmed.ncbi.nlm.nih.gov/16301661
https://pubmed.ncbi.nlm.nih.gov/16301661