Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Benjamin T. Ledford"'
Publikováno v:
Seminars in Cell & Developmental Biology. 128:145-153
Keratin (KRT), a natural fibrous structural protein, can be classified into two categories: "soft" cytosolic KRT that is primarily found in the epithelia tissues (e.g., skin, the inner lining of digestive tract) and "hard" KRT that is mainly found in
Autor:
Benjamin T. Ledford, Thomas G. Wyatt, Johnny Vang, Jenna Weiss, Nick D. Tsihlis, Melina R. Kibbe
Publikováno v:
Particle & Particle Systems Characterization.
Autor:
Benjamin T. Ledford, Adam W. Akerman, Kui Sun, David C. Gillis, Jenna M. Weiss, Johnny Vang, Smaranda Willcox, Tristan D. Clemons, Hiroaki Sai, Ruomeng Qiu, Mark R. Karver, Jack D. Griffith, Nick D. Tsihlis, Samuel I. Stupp, John S. Ikonomidis, Melina R. Kibbe
Publikováno v:
ACS Nano
An abdominal aortic aneurysm (AAA) is a localized dilation of the aorta located in the abdomen that poses a severe risk of death when ruptured. The cause of AAA is not fully understood, but degradation of medial elastin due to elastolytic matrix meta
Publikováno v:
ACS Applied Bio Materials. 3:2150-2159
Small-diameter expanded polytetrafluoroethylene (ePTFE) graft surfaces have poor long-term patency due to limited endothelial cell (EC) coverage and anastomotic intimal hyperplasia. Multifunctional...
Publikováno v:
ACS applied bio materials. 3(4)
Small-diameter expanded polytetrafluoroethylene (ePTFE) graft surfaces have poor long-term patency due to limited endothelial cell (EC) coverage and anastomotic intimal hyperplasia. Multifunctional elastomers that coat the ePTFE graft surface to prom
Autor:
Lijuan Kan, Aubrie Smith, Miao Chen, Benjamin T Ledford, Huimin Fan, Zhongmin Liu, Jia-Qiang He
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144513 (2015)
Recent clinical trials using c-kit+ human cardiac stem cells (CSCs) demonstrated promising results in increasing cardiac function and improving quality of life. However, CSC efficiency is low, likely due to limited cell survival and engraftment after
Externí odkaz:
https://doaj.org/article/8ba41e7f3907410ba420dce438f43b36
Autor:
Zhongmin Liu, Huimin Fan, Miao Chen, Catherine Barron, Mark Van Dyke, Jia-Qiang He, Benjamin T. Ledford, Jamelle Simmons
Publikováno v:
Stem Cells and Development. 26:888-900
Stem cell-based therapies have demonstrated great potential for the treatment of cardiac diseases, for example, myocardial infarction; however, low cell viability, low retention/engraftment, and uncontrollable in vivo differentiation after transplant
Autor:
Jia-Qiang He, Zayd Farah, Miao Chen, Zhongmin Liu, Catherine Barron, Benjamin T. Ledford, Huimin Fan
Publikováno v:
Microvascular Research. 110:48-55
Background and aim Although femoral artery ligation-induced ischemia is commonly used in C57BL/6 or Balb/c mice, direct comparisons between femoral artery/vein (FAV) versus femoral artery (FA) excisions have not been reported. The goal of the present
Autor:
Mark R. Karver, Edward Moreira Bahnson, Melina R. Kibbe, Erica B. Peters, Samuel I. Stupp, Stacey M. Chin, Nick D. Tsihlis, Bruno Musetti, Benjamin T. Ledford
Publikováno v:
Advanced healthcare materials. 8(3)
Nanomedicine is a promising, noninvasive approach to reduce atherosclerotic plaque burden. However, drug delivery is limited without the ability of nanocarriers to sense and respond to the diseased microenvironment. In this study, we developed nanoma
Autor:
Huimin Fan, Patrick Thayer, Guohua Cao, Lijuan Kan, Jia-Qiang He, Aaron S. Goldstein, Benjamin T. Ledford, Miao Chen
Publikováno v:
Experimental Cell Research. 347:143-152
Electrospun microfiber meshes have been shown to support the proliferation and differentiation of many types of stem cells, but the phenotypic fate of c-kit(+) human cardiac stem cells (hCSCs) have not been explored. To this end, we utilized thin (~5