Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Benjamin T. Himes"'
Autor:
Julio F. Inocencio, Stefan Mitrasinovic, Mohammad Asad, Ian F. Parney, Xingxing Zang, Benjamin T. Himes
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Immune checkpoint (IC) inhibition in glioblastoma (GBM) has not shown promising results in the last decade compared to other solid tumors. Several factors contributing to the lack of immunotherapy response include the profound immunosuppressive natur
Externí odkaz:
https://doaj.org/article/d88b8cd80c534ebc81fe4e751ea86ec8
Autor:
Cecile Riviere-Cazaux, Karishma Rajani, Masum Rahman, Juhee Oh, Desmond A. Brown, Jaclyn F. White, Benjamin T. Himes, Ignacio Jusue-Torres, Moses Rodriguez, Arthur E. Warrington, Sani H. Kizilbash, William F. Elmquist, Terry C. Burns
Publikováno v:
Fluids and Barriers of the CNS, Vol 20, Iss 1, Pp 1-17 (2023)
Abstract Background Microdialysis is a technique that can be utilized to sample the interstitial fluid of the central nervous system (CNS), including in primary malignant brain tumors known as gliomas. Gliomas are mainly accessible at the time of sur
Externí odkaz:
https://doaj.org/article/b01726b9a3c24b95811a6ea5c664f995
Blood-brain barrier disruption defines the extracellular metabolome of live human high-grade gliomas
Autor:
Cecile Riviere-Cazaux, Lucas P. Carlstrom, Karishma Rajani, Amanda Munoz-Casabella, Masum Rahman, Ali Gharibi-Loron, Desmond A. Brown, Kai J. Miller, Jaclyn J. White, Benjamin T. Himes, Ignacio Jusue-Torres, Samar Ikram, Seth C. Ransom, Renee Hirte, Ju-Hee Oh, William F. Elmquist, Jann N. Sarkaria, Rachael A. Vaubel, Moses Rodriguez, Arthur E. Warrington, Sani H. Kizilbash, Terry C. Burns
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
Abstract The extracellular microenvironment modulates glioma behaviour. It remains unknown if blood-brain barrier disruption merely reflects or functionally supports glioma aggressiveness. We utilised intra-operative microdialysis to sample the extra
Externí odkaz:
https://doaj.org/article/df7819129fee4a19804cd898e7b157b6
Autor:
Jun Liu, Xiaoying Wang, Ann T. Chen, Xingchun Gao, Benjamin T. Himes, Hongyi Zhang, Zeming Chen, Jianhui Wang, Wendy C. Sheu, Gang Deng, Yang Xiao, Pan Zou, Shenqi Zhang, Fuyao Liu, Yong Zhu, Rong Fan, Toral R. Patel, W. Mark Saltzman, Jiangbing Zhou
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Improved treatment of glioblastoma (GBM) can be achieved by inducing differentiation of glioblastoma stem cells (GSCs). Here, the authors show that zinc finger protein 117 (ZNF117) is a regulator of GSC differentiation via Notch signaling through int
Externí odkaz:
https://doaj.org/article/45a610fac96344a087a5f202c74fb20b
Autor:
Benjamin T. Himes, Philipp A. Geiger, Katayoun Ayasoufi, Adip G. Bhargav, Desmond A. Brown, Ian F. Parney
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Glioblastoma (GBM) is the most common primary brain tumor in adults an carries and carries a terrible prognosis. The current regiment of surgical resection, radiation, and chemotherapy has remained largely unchanged in recent years as new therapeutic
Externí odkaz:
https://doaj.org/article/727b372967e7405db471441362f7faf8
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Diffuse midline gliomas harboring the H3 K27M mutation—including the previously named diffuse intrinsic pontine glioma (DIPG)—are lethal high-grade pediatric brain tumors that are inoperable and without cure. Despite numerous clinical trials, the
Externí odkaz:
https://doaj.org/article/b98560e9e84346d7917f5f13c6a93934
Autor:
Zachariah P. Tritz, Katayoun Ayasoufi, Delaney M. Wolf, Carley A. Owens, Courtney S. Malo, Benjamin T. Himes, Cori E. Fain, Emma N. Goddery, Lila T. Yokanovich, Fang Jin, Michael J. Hansen, Ian F. Parney, Chensu Wang, Kelly D. Moynihan, Darrell J. Irvine, K. Dane Wittrup, Rosa M. Diaz Marcano, Richard G. Vile, Aaron J. Johnson
Publikováno v:
Cancer Immunology Research. :OF1-OF14
Glioblastoma (GBM) is the most common malignant brain tumor in adults, responsible for approximately 225,000 deaths per year. Despite preclinical successes, most interventions have failed to extend patient survival by more than a few months. Treatmen
Autor:
Panagiotis Kerezoudis, Evangelia N. Kerezoudi, Abdurehman Choudhry, Benjamin T. Himes, Ian F. Parney
Publikováno v:
Neurosurgery. 92:464-471
Autor:
Aaron J. Johnson, Richard G. Vile, Rosa M. Diaz Marcano, K. Dane Wittrup, Darrell J. Irvine, Kelly D. Moynihan, Chensu Wang, Ian F. Parney, Michael J. Hansen, Fang Jin, Lila T. Yokanovich, Emma N. Goddery, Cori E. Fain, Benjamin T. Himes, Courtney S. Malo, Carley A. Owens, Delaney M. Wolf, Katayoun Ayasoufi, Zachariah P. Tritz
Supplemental Figure 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8af07029eab8305dbe3c80548980b1f
https://doi.org/10.1158/2326-6066.22713695.v1
https://doi.org/10.1158/2326-6066.22713695.v1
Autor:
Aaron J. Johnson, Richard G. Vile, Rosa M. Diaz Marcano, K. Dane Wittrup, Darrell J. Irvine, Kelly D. Moynihan, Chensu Wang, Ian F. Parney, Michael J. Hansen, Fang Jin, Lila T. Yokanovich, Emma N. Goddery, Cori E. Fain, Benjamin T. Himes, Courtney S. Malo, Carley A. Owens, Delaney M. Wolf, Katayoun Ayasoufi, Zachariah P. Tritz
Glioblastoma (GBM) is the most common malignant brain tumor in adults, responsible for approximately 225,000 deaths per year. Despite preclinical successes, most interventions have failed to extend patient survival by more than a few months. Treatmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::322631adc5451f9918eda0c9cbff9d47
https://doi.org/10.1158/2326-6066.c.6620888
https://doi.org/10.1158/2326-6066.c.6620888