Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Benjamin T. Goult"'
Autor:
Nicole Morales-Camilo, Jingzhun Liu, Manuel J. Ramírez, Patricio Canales-Salgado, Juan José Alegría, Xuyao Liu, Hui Ting Ong, Nelson P. Barrera, Angélica Fierro, Yusuke Toyama, Benjamin T. Goult, Yilin Wang, Yue Meng, Ryosuke Nishimura, Kedsarin Fong-Ngern, Christine Siok Lan Low, Pakorn Kanchanawong, Jie Yan, Andrea Ravasio, Cristina Bertocchi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Force transmission through adherens junctions (AJs) is crucial for multicellular organization, wound healing and tissue regeneration. Recent studies shed light on the molecular mechanisms of mechanotransduction at the AJs. However, the canon
Externí odkaz:
https://doaj.org/article/6be83a197f51435ca5f41022c5884809
Autor:
Daniel Newman, Lorna E. Young, Thomas Waring, Louise Brown, Katarzyna I. Wolanska, Ewan MacDonald, Arthur Charles-Orszag, Benjamin T. Goult, Patrick T. Caswell, Tetsushi Sakuma, Takashi Yamamoto, Laura M. Machesky, Mark R. Morgan, Tobias Zech
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113554- (2023)
Summary: Cell invasion is a multi-step process, initiated by the acquisition of a migratory phenotype and the ability to move through complex 3D extracellular environments. We determine the composition of cell-matrix adhesion complexes of invasive br
Externí odkaz:
https://doaj.org/article/cc9ca5676a6c4c1a8c9af06188019194
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/c89494250b4d46058ded1a04ef405265
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
The Mercator projection map of the world provides a useful, but distorted, view of the relative scale of countries. Current cellular models suffer from a similar distortion. Here, we undertook an in-depth structural analysis of the molecular dimensio
Externí odkaz:
https://doaj.org/article/0e9ea65beb5d4322b3de1974ba450822
Publikováno v:
Biology, Vol 12, Iss 7, p 954 (2023)
Integrin receptors are essential contributors to neurite outgrowth and axon elongation. Activated integrins engage components of the extracellular matrix, enabling the growth cone to form point contacts, which connect the extracellular substrate to d
Externí odkaz:
https://doaj.org/article/cb7c532bebf54f07a9527705e71d8ef6
Autor:
Latifeh Azizi, Alana R. Cowell, Vasyl V. Mykuliak, Benjamin T. Goult, Paula Turkki, Vesa P. Hytönen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Talin-1 is a key component of the multiprotein adhesion complexes which mediate cell migration, adhesion and integrin signalling and has been linked to cancer in several studies. We analysed talin-1 mutations reported in the Catalogue of Som
Externí odkaz:
https://doaj.org/article/a28e1b8a9ed84d7da01db2876fbbed20
Autor:
Mitro Miihkinen, Max L.B. Grönloh, Ana Popović, Helena Vihinen, Eija Jokitalo, Benjamin T. Goult, Johanna Ivaska, Guillaume Jacquemet
Publikováno v:
Cell Reports, Vol 36, Iss 11, Pp 109716- (2021)
Summary: Filopodia assemble unique integrin-adhesion complexes to sense the extracellular matrix. However, the mechanisms of integrin regulation in filopodia are poorly defined. Here, we report that active integrins accumulate at the tip of myosin-X
Externí odkaz:
https://doaj.org/article/58b81ee3731645c28b9246624729fde9
Publikováno v:
Cells, Vol 11, Iss 19, p 3039 (2022)
β2 integrins are expressed on all leukocytes. Precise regulation of the β2 integrin is critical for leukocyte adhesion and trafficking. In neutrophils, β2 integrins participate in slow rolling. When activated by inside–out signaling, fully activ
Externí odkaz:
https://doaj.org/article/47641a74f1a74fac894bf94516fd27e2
Autor:
Benjamin T. Goult
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
One of the major unsolved mysteries of biological science concerns the question of where and in what form information is stored in the brain. I propose that memory is stored in the brain in a mechanically encoded binary format written into the confor
Externí odkaz:
https://doaj.org/article/147f1070fcb7461cbd5fd2df82a322c7
Autor:
Rejina B. Khan, Benjamin T. Goult
Publikováno v:
Frontiers in Molecular Biosciences, Vol 6 (2019)
The advent of cell-cell and cell-extracellular adhesion enabled cells to interact in a coherent manner, forming larger structures and giving rise to the development of tissues, organs and complex multicellular life forms. The development of such orga
Externí odkaz:
https://doaj.org/article/ccf37c67070e407ba3884bd46f5e5a75