Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Benjamin T Wilks"'
Autor:
Reinier J de Vries, Stephanie E J Cronin, Padraic Romfh, Casie A Pendexter, Rohil Jain, Benjamin T Wilks, Siavash Raigani, Thomas M van Gulik, Peili Chen, Heidi Yeh, Korkut Uygun, Shannon N Tessier
Publikováno v:
PLoS ONE, Vol 16, Iss 10, p e0258833 (2021)
Ischemia reperfusion injury (IRI) is a critical problem in liver transplantation that can lead to life-threatening complications and substantially limit the utilization of livers for transplantation. However, because there are no early diagnostics av
Externí odkaz:
https://doaj.org/article/0240f347847f42e788e242f973e8b22a
Autor:
Mohammadreza Mojoudi, McLean S. Taggart, Anil Kharga, Huyun Chen, Antonia T. Dinicu, Benjamin T. Wilks, James F. Markmann, Mehmet Toner, Shannon N. Tessier, Heidi Yeh, Korkut Uygun
Publikováno v:
Heliyon, Vol 10, Iss 8, Pp e29519- (2024)
Background: Liver donation after cardiac death (DCD) makes up a small percentage of the organs used in transplantation and poses a higher risk of graft loss compared to donation after brain death (DBD); this is a result of ischemia reperfusion for wh
Externí odkaz:
https://doaj.org/article/bad439d98e9d4ac0b44a99548ad3eda6
Autor:
Shannon N. Tessier, Reinier J. de Vries, Casie A. Pendexter, Stephanie E. J. Cronin, Sinan Ozer, Ehab O. A. Hafiz, Siavash Raigani, Joao Paulo Oliveira-Costa, Benjamin T. Wilks, Manuela Lopera Higuita, Thomas M. van Gulik, Osman Berk Usta, Shannon L. Stott, Heidi Yeh, Martin L. Yarmush, Korkut Uygun, Mehmet Toner
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
The limited preservation duration of donor organs is a big problem. Here the authors report a method for the freezing of whole rat livers at temperatures between −10 °C to −15 °C for up to 5 days, based on freeze-tolerant wood frogs, and term t
Externí odkaz:
https://doaj.org/article/033d5d8cc0c846d7b139393dd1af1722
Autor:
Benjamin T. Wilks, Elisabeth B. Evans, Andrew Howes, Caitlin M. Hopkins, Morcos N. Nakhla, Geoffrey Williams, Jeffrey R. Morgan
Publikováno v:
Advanced Science, Vol 9, Iss 10, Pp n/a-n/a (2022)
Abstract Dysregulation of extracellular matrix (ECM) synthesis, organization, and mechanics are hallmark features of diseases like fibrosis and cancer. However, most in vitro models fail to recapitulate the three‐dimensional (3D) multi‐scale hier
Externí odkaz:
https://doaj.org/article/93b5244f02964469b796c54dceb627d2
Publikováno v:
Frontiers in Optics + Laser Science 2022 (FIO, LS).
We report a fiber diameter measurement algorithm for second harmonic generation imaging of collagen-based tissue constructs based on vessel enhancement and centerline extraction.
Publikováno v:
American Journal of Transplantation. 22:1487-1488
Autor:
Thomas M. van Gulik, Siavash Raigani, Korkut Uygun, Peili Chen, Stephanie E.J. Cronin, Reinier J. de Vries, Padraic Romfh, Benjamin T. Wilks, Shannon N. Tessier, Rohil Jain, Casie A. Pendexter, Heidi Yeh
Publikováno v:
PLoS ONE, Vol 16, Iss 10, p e0258833 (2021)
PLoS ONE, 16(10 October):e0258833. Public Library of Science
PLoS ONE, Vol 16, Iss 10 (2021)
PLoS ONE
PLoS ONE, 16(10 October):e0258833. Public Library of Science
PLoS ONE, Vol 16, Iss 10 (2021)
PLoS ONE
Ischemia reperfusion injury (IRI) is a critical problem in liver transplantation that can lead to life-threatening complications and substantially limit the utilization of livers for transplantation. However, because there are no early diagnostics av
Publikováno v:
Acta biomaterialia. 81
Extracellular matrix composition and organization play a crucial role in numerous biological processes ranging from cell migration, differentiation, survival and metastasis. Consequently, there have been significant efforts towards the development of
Publikováno v:
SLAS technology. 23(3)
Accurately predicting the human response to new compounds is critical to a wide variety of industries. Standard screening pipelines (including both in vitro and in vivo models) often lack predictive power. Three-dimensional (3D) culture systems of hu
Autor:
Toni-Marie Achilli, Kim Boekelheide, Marguerite M. Vantangoli, Sean P. Curran, Benjamin T. Wilks, Jeffrey R. Morgan, Elizabeth Leary
Publikováno v:
TECHNOLOGY. :54-63
None of the ABCG2 inhibitors are effective clinically against multidrug resistant tumors overexpressing ABCG2. New in vitro models are needed to characterize inhibitors and discover new ones. We report a 3D spheroid model and image-based method to qu