Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Benjamin T Aldrich"'
Autor:
Jessica M Skeie, Benjamin T Aldrich, Andrew S Goldstein, Gregory A Schmidt, Cynthia R Reed, Mark A Greiner
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0192287 (2018)
The objective of this study was to characterize the proteome of the corneal endothelial cell layer and its basement membrane (Descemet membrane) in humans with various severities of type II diabetes mellitus compared to controls, and identify differe
Externí odkaz:
https://doaj.org/article/2c392cd217c148839833c3351dfce229
Autor:
Bridget C Lear, Eric J Darrah, Benjamin T Aldrich, Senetibeb Gebre, Robert L Scott, Howard A Nash, Ravi Allada
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e78147 (2013)
In the fruit fly Drosophila melanogaster, a network of circadian pacemaker neurons drives daily rhythms in rest and activity. The ion channel NARROW ABDOMEN (NA), orthologous to the mammalian sodium leak channel NALCN, functions downstream of the mol
Externí odkaz:
https://doaj.org/article/18e1130d93ec46f0859279232e9c7e20
Autor:
Michael D. Wagoner, Laura R. Bohrer, Benjamin T. Aldrich, Mark A. Greiner, Robert F. Mullins, Kristan S. Worthington, Budd A. Tucker, Luke A. Wiley
Publikováno v:
Biology Open, Vol 7, Iss 5 (2018)
The purpose of this study was to devise a strategy for the derivation of corneal endothelial cells (CEnCs) from adult fibroblast-derived induced pluripotent stem cells (iPSCs). IPSCs were generated from an adult human with normal ocular history via e
Externí odkaz:
https://doaj.org/article/390cee8a22654e328b947693ac197a23
Autor:
Jessica M. Skeie, Jennifer J. Ling, Mark A. Greiner, Youssef W. Naguib, M. Bridget Zimmerman, Benjamin T. Aldrich, Aliasger K. Salem, Gregory A. Schmidt, Darryl Y. Nishimura
Publikováno v:
Cornea. 39:1285-1290
Purpose To determine whether ubiquinol improves mitochondrial function and cell viability in human donor corneal endothelial cells during hypothermic corneal tissue storage. Methods Endothelial cell Descemet membrane tissues were treated with 10 μM
Autor:
Jessica M. Skeie, Khoa D. Tran, Claudio Gatto, Cynthia R. Reed, Jana DʼAmato Tóthová, Mark A. Greiner, Laura Giurgola, Gregory A. Schmidt, Christine M Kondratick, Benjamin T. Aldrich, Mark A. Terry
Publikováno v:
Cornea. 39:110-117
Purpose To determine the concentration of amphotericin B that would be both effective against Candida albicans contamination and safe for corneal endothelial cells (CECs) in cold storage conditions. Methods Triplicate media cultures were inoculated w
Autor:
Jessica M. Skeie, Benjamin T. Aldrich, Gregory A. Schmidt, Mark A. Greiner, Cheryl L Wang, Darryl Y. Nishimura
Publikováno v:
Investigative Ophthalmology & Visual Science
Mitochondrial function is essential for the viability of aerobic eukaryotic cells, as mitochondria provide energy through the generation of adenosine triphosphate (ATP), regulate cellular metabolism, provide redox balancing, participate in immune sig
Autor:
Mark A. Greiner, M. Bridget Zimmerman, Benjamin T. Aldrich, Chris Conwell, Cynthia R. Reed, Jennifer J. Ling, Jennifer Y. Li, Jessica M. Skeie, Tiffany Ramirez, Kimberlee A. Burckart, Gregory A. Schmidt, Ralph Kyrillos
Publikováno v:
Cornea. 40(3)
Purpose To assess how trypan blue staining affects Descemet membrane endothelial keratoplasty (DMEK) graft visibility and corneal endothelial cell (CEC) mitochondrial respiration. Methods DMEK grafts (n = 20) were stained with trypan blue 0.06% for 1
Autor:
Andrew S. Goldstein, Benjamin T. Aldrich, Mark A. Greiner, Jessica M. Skeie, Gregory A. Schmidt, Cynthia R. Reed, M. Bridget Zimmerman
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics. 34:692-699
To determine how the Rho kinase inhibitor, ripasudil, affects metabolic function and cell viability in donor human corneal endothelial cells (HCECs).Endothelial cell-Descemet membrane (EDM) tissues were treated with 10 μM ripasudil and assayed for m
Autor:
Mark A. Greiner, Benjamin T. Aldrich, M. Bridget Zimmerman, Pamela C. Carter, Jessica M. Skeie, Gregory A. Schmidt, Kimberlee A. Burckart, Cynthia R. Reed, Chase A. Liaboe
Publikováno v:
Cornea. 36:561-566
PURPOSE To quantify changes in endothelial cell density (ECD) of donor corneal tissue in relation to the presence or absence of a medical history of diabetes mellitus diagnosis, treatment, and complications. METHODS A retrospective review was perform
Autor:
M. Bridget Zimmerman, Michael D. Wagoner, Gregory A. Schmidt, Cynthia R. Reed, Benjamin T. Aldrich, Jessica M. Skeie, Mark A. Greiner, Kenneth M. Goins, Jesse M. Vislisel
Publikováno v:
Ophthalmology. 124:36-42
Purpose To determine the incidence of positive corneoscleral donor rim fungal cultures after keratoplasty and to report clinical outcomes of grafts with culture-positive donor rims. Design Retrospective cohort study. Participants Consecutive donor co