Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Benjamin T, Kopp"'
Autor:
Chandra L. Shrestha, Shuzhong Zhang, Benjamin Wisniewski, Stephanie Häfner, Jonathan Elie, Laurent Meijer, Benjamin T. Kopp
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Abstract Cystic fibrosis (CF) is characterized by chronic bacterial infections and heightened inflammation. Widespread ineffective antibiotic use has led to increased isolation of drug resistant bacterial strains from respiratory samples. (R)-roscovi
Externí odkaz:
https://doaj.org/article/b28faafa018e4d7a8701559c160e0ad9
Autor:
Shuzhong Zhang, Chandra L. Shrestha, Benjamin L. Wisniewski, Hanh Pham, Xucheng Hou, Wenqing Li, Yizhou Dong, Benjamin T. Kopp
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Macrophage dysfunction is fundamentally related to altered immunity in cystic fibrosis (CF). How genetic deficits in the cystic fibrosis transmembrane conductance regulator (CFTR) lead to these defects remains unknown. Rapid advances in genomic editi
Externí odkaz:
https://doaj.org/article/e67b7af5b37044f380f2de3aa8a546f2
Autor:
Graham Devereux, Danielle Wrolstad, Stephen J Bourke, Cori L Daines, Simon Doe, Ryan Dougherty, Rose Franco, Alastair Innes, Benjamin T Kopp, Jorge Lascano, Daniel Layish, Gordon MacGregor, Lorna Murray, Daniel Peckham, Vincenzina Lucidi, Emma Lovie, Jennifer Robertson, Douglas J Fraser-Pitt, Deborah A O'Neil
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0242945 (2020)
BackgroundEmerging data suggests a possible role for cysteamine as an adjunct treatment for pulmonary exacerbations of cystic fibrosis (CF) that continue to be a major clinical challenge. There are no studies investigating the use of cysteamine in pu
Externí odkaz:
https://doaj.org/article/eae90fa4cc0e475e8b1524d66ccc66a6
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0213092 (2019)
[This corrects the article DOI: 10.1371/journal.pone.0096681.].
Externí odkaz:
https://doaj.org/article/1b33dbb4d5124325bbbf517c425f5b5f
Autor:
Courtney Pugh, Rachel N. Zeno, Joseph Stanek, Michelle Gillespie, Benjamin T. Kopp, Susan E. Creary
Publikováno v:
Journal of Pediatric Hematology/Oncology.
Autor:
Rachel N. Zeno, Joseph Stanek, Courtney Pugh, Michelle Gillespie, Benjamin T. Kopp, Susan Creary
Publikováno v:
Blood advances.
People with sickle cell disease (pwSCD) are at risk of developing lung conditions that complicate their SCD but often face health care access barriers. An interdisciplinary clinic providing pulmonary care for pwSCD was created in 2014 at the Nationwi
Autor:
Shahid Sheikh, Rodney D. Britt, Nancy A. Ryan‐Wenger, Aiman Q. Khan, Brandon W. Lewis, Courtney Gushue, Hazel Ozuna, Devi Jaganathan, Karen McCoy, Benjamin T. Kopp
Publikováno v:
Pediatric pulmonology.
Cystic fibrosis (CF) is a multisystem disease with progressive deterioration. Recently, CF transmembrane conductance regulator (CFTR) modulator therapies were introduced that repair underlying protein defects. Objective of this study was to determine
Autor:
S. Christy Sadreameli, Benjamin T. Kopp, Deborah R. Liptzin, Devika R. Rao, Rory Kamerman-Kretzmer, Folashade Afolabi, Vivek Balasubramaniam
Publikováno v:
Annals of the American Thoracic Society
Autor:
Chandra L Shrestha, Kaivon D Assani, Hannah Rinehardt, Florentina Albastroiu, Shuzhong Zhang, Richard Shell, Amal O Amer, Larry S Schlesinger, Benjamin T Kopp
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186169 (2017)
Members of the Burkholderia cepacia complex are virulent, multi-drug resistant pathogens that survive and replicate intracellularly in patients with cystic fibrosis (CF). We have discovered that B. cenocepacia cannot be cleared from CF macrophages du
Externí odkaz:
https://doaj.org/article/04f3c4965e0c4d69b8e9c95c8806aa5b
Autor:
Sabrina Palacios, Katelyn Krivchenia, Mariah Eisner, Bailey Young, Octavio Ramilo, Asuncion Mejias, Simon Lee, Benjamin T. Kopp
Publikováno v:
Pediatric pulmonology. 57(10)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes long-term pulmonary sequelae in adults, but little is known about pulmonary outcomes in pediatrics.The aim of this study was to describe long-term subjective and objective pulmonary