Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Benjamin Szlyk"'
Autor:
Sanda Ljubicic, Klaudia Polak, Accalia Fu, Jessica Wiwczar, Benjamin Szlyk, Yigang Chang, Juan C. Alvarez-Perez, Gregory H. Bird, Loren D. Walensky, Adolfo Garcia-Ocaña, Nika N. Danial
Publikováno v:
Cell Reports, Vol 10, Iss 4, Pp 497-504 (2015)
Strategies that simultaneously enhance the survival and glucose responsiveness of insulin-producing β cells will greatly augment β cell replacement therapies in type 1 diabetes (T1D). We show that genetic and pharmacologic mimetics of the phosphory
Externí odkaz:
https://doaj.org/article/0507c2fc999c4b9fb8688a6e0e999254
Autor:
Nika N. Danial, Yigang Chang, Adolfo Garcia-Ocaña, Loren D. Walensky, Sanda Ljubicic, Accalia Fu, Gregory H. Bird, Klaudia Polak, Jessica Wiwczar, Benjamin Szlyk, Juan Carlos Alvarez-Perez
Publikováno v:
Cell Reports, Vol 10, Iss 4, Pp 497-504 (2015)
SummaryStrategies that simultaneously enhance the survival and glucose responsiveness of insulin-producing β cells will greatly augment β cell replacement therapies in type 1 diabetes (T1D). We show that genetic and pharmacologic mimetics of the ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3dffcfdbfd8145b55e97cabbf27a2fa
https://doi.org/10.1016/j.celrep.2014.12.056
https://doi.org/10.1016/j.celrep.2014.12.056
Autor:
Gary Yellen, Jill K. Fisher, Jessica Wiwczar, Alfredo Giménez-Cassina, Benjamin Szlyk, Andrew Lutas, Klaudia Polak, Geoffrey R. Tanner, Nika N. Danial, Juan Ramón Martínez-François
Publikováno v:
Neuron. 74:719-730
SummaryNeuronal excitation can be substantially modulated by alterations in metabolism, as evident from the anticonvulsant effect of diets that reduce glucose utilization and promote ketone body metabolism. We provide genetic evidence that BAD, a pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8857a3d769ad5ceb300c33e16da5aea8
https://doi.org/10.1016/j.neuron.2012.03.032
https://doi.org/10.1016/j.neuron.2012.03.032
Autor:
Nika N. Danial, Gregory H. Bird, Loren D. Walensky, Benjamin Szlyk, Mayowa A. Osundiji, Elaura Patton, Sanda Ljubicic, Craig R. Braun, Franz M. Matschinsky
Glucokinase is a glucose-phosphorylating enzyme that regulates insulin release and hepatic metabolism, and its loss-of-function is implicated in the pathogenesis of diabetes. Glucokinase activators (GKAs) are attractive therapeutics in diabetes, howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3798043dc7dbd8fa288ee6f26801c5e
https://europepmc.org/articles/PMC4084830/
https://europepmc.org/articles/PMC4084830/
Autor:
Klaudia Polak, Sheene Kim, Jill K. Fisher, Gary W. Cline, Hu Huang, Benjamin Szlyk, Dae Ho Lee, Gerald I. Shulman, Alfredo Giménez-Cassina, Nika N. Danial, Alberto Distefano, Kirsten Robertson, Marina Godes, Muhammed A. Yildirim, Cheol Soo Choi, Ameya Kulkarni, Varman T. Samuel, Elaura Patton, Young-Bum Kim, Mayowa A. Osundiji, Luisa Garcia-Haro, Jessica Wiwczar, Elizabeth A. Lane
Publikováno v:
Cell metabolism. 19(2)
Summary The homeostatic balance of hepatic glucose utilization, storage, and production is exquisitely controlled by hormonal signals and hepatic carbon metabolism during fed and fasted states. How the liver senses extracellular glucose to cue glucos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2947ad9fc6f0b9a54911344820f1d6ae
https://pubmed.ncbi.nlm.nih.gov/24506868
https://pubmed.ncbi.nlm.nih.gov/24506868