Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Benjamin Soibam"'
Autor:
Benjamin Soibam, Gregg Roman
Publikováno v:
BMC Research Notes, Vol 17, Iss 1, Pp 1-5 (2024)
Abstract Summary In genetic mapping studies involving many individuals, genome-wide markers such as single nucleotide polymorphisms (SNPs) can be detected using different methods. However, it comes with some errors. Some SNPs associated with diseases
Externí odkaz:
https://doaj.org/article/6afdca505ad1456f82bdf8ab428a532e
Autor:
Rui Liang, Xiaopeng Shen, Fan Wang, Xin Wang, Alex DesJarlais, Anam Syed, Raymond Saba, Zhi Tan, Fang Yu, Xuan Ji, Shreesti Shrestha, Yinghong Ren, Jin Yang, Yoonjung Park, Robert J. Schwartz, Benjamin Soibam, Bradley K. McConnell, M. David Stewart, Ashok Kumar, Yu Liu
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 6, Pp 2174-2186 (2021)
Abstract Background Skeletal muscle atrophy is a debilitating complication of many chronic diseases, disuse conditions, and ageing. Genome‐wide gene expression analyses have identified that elevated levels of microRNAs encoded by the H19X locus are
Externí odkaz:
https://doaj.org/article/bd56645cb21b4cd6bfe0a9c549f489cf
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-10 (2021)
Abstract Background Chromosomes are organized into units called topologically associated domains (TADs). TADs dictate regulatory landscapes and other DNA-dependent processes. Even though various factors that contribute to the specification of TADs ha
Externí odkaz:
https://doaj.org/article/98eed906548147cda099c0c0d4be0f16
Autor:
Neha Tandon, Kristina Goller, Fan Wang, Benjamin Soibam, Mihai Gagea, Abhinav K. Jain, Robert J. Schwartz, Yu Liu
Publikováno v:
EBioMedicine, Vol 50, Iss , Pp 55-66 (2019)
Background: Mesoderm Posterior 1 (MESP1) belongs to the family of basic helix-loop-helix transcription factors. It is a master regulator of mesendoderm development, leading to formation of organs such as heart and lung. However, its role in adult pat
Externí odkaz:
https://doaj.org/article/44ee2716a52d4da3836d978b241668c5
Autor:
Benjamin Soibam
Publikováno v:
Non-Coding RNA, Vol 8, Iss 3, p 41 (2022)
This study explored the relationship between 3D genome organization and RNA–DNA triplex-forming sites of long noncoding RNAs (lncRNAs), a group of RNAs that do not code for proteins but are important factors regulating different aspects of genome a
Externí odkaz:
https://doaj.org/article/6dd7f005a34948d1af40d22cc9d4f57f
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-13 (2018)
Abstract Background Comprehensive understanding of intratumor heterogeneity requires identification of molecular markers, which are capable of differentiating different subpopulations and which also have clinical significance. One important tool that
Externí odkaz:
https://doaj.org/article/7094c3fe1d314a5a981d9efe902fa60e
Publikováno v:
Data in Brief, Vol 9, Iss C, Pp 699-703 (2016)
Small RNAs from early neural (i.e., Noggin-expressing, or NOG) and epidermal (expressing a constitutively active BMP4 receptor, CABR) ectoderm in Xenopus laevis were sequenced to identify microRNAs (miRs) expressed in each tissue. Argonaute-associate
Externí odkaz:
https://doaj.org/article/e6d80502f0cd4593bd2ab66988986d6e
Autor:
Nicolas Valenzuela, Qiying Fan, Faisal Fa'ak, Benjamin Soibam, Harika Nagandla, Yu Liu, Robert J. Schwartz, Bradley K. McConnell, M. David Stewart
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 3, Pp 335-345 (2016)
HIRA is the histone chaperone responsible for replication-independent incorporation of histone variant H3.3 within gene bodies and regulatory regions of actively transcribed genes, and within the bivalent promoter regions of developmentally regulated
Externí odkaz:
https://doaj.org/article/21433f80557d434da98d5493f24423dc
Autor:
M. David Stewart, Suhujey Lopez, Harika Nagandla, Benjamin Soibam, Ashley Benham, Jasmine Nguyen, Nicolas Valenzuela, Harry J. Wu, Alan R. Burns, Tara L. Rasmussen, Haley O. Tucker, Robert J. Schwartz
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 3, Pp 347-359 (2016)
The Smyd1 gene encodes a lysine methyltransferase specifically expressed in striated muscle. Because Smyd1-null mouse embryos die from heart malformation prior to formation of skeletal muscle, we developed a Smyd1 conditional-knockout allele to deter
Externí odkaz:
https://doaj.org/article/7624d789c2964ec3942e5143c4307fb0
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191892 (2018)
Liver-like organoids that recapitulate the complex functions of the whole liver by combining cells, scaffolds, and mechanical or chemical cues are becoming important models for studying liver biology and drug metabolism. The advantages of growing cel
Externí odkaz:
https://doaj.org/article/a7f6db80f6344244bd282bf7ff596f97