Zobrazeno 1 - 10
of 193
pro vyhledávání: '"Benjamin Schmid"'
Autor:
Juan Guzman, Katrin Weigelt, Angela Neumann, Philipp Tripal, Benjamin Schmid, Zoltán Winter, Ralph Palmisano, Zoran Culig, Marcus V. Cronauer, Paul Muschler, Bernd Wullich, Helge Taubert, Sven Wach
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background The androgen/androgen receptor (AR)-signaling axis plays a central role in prostate cancer (PCa). Upon androgen-binding the AR dimerizes with another AR, and translocates into the nucleus where the AR-dimer activates/inactivates a
Externí odkaz:
https://doaj.org/article/540315149f484863b24ccb2561a69445
Autor:
Luisana Duque Villegas, Abinaya Chandrasekaran, Sofie Amalie Flintholm Andersen, Anne Nørremølle, Benjamin Schmid, Mahmoud A. Pouladi, Kristine Freude
Publikováno v:
Stem Cell Research, Vol 77, Iss , Pp 103408- (2024)
Neurogenin 2 (NGN2), a neuronal transcription factor, can expedite differentiation of stem cells into mature glutamatergic neurons. We have utilized an allelic series of previously published and characterized isogenic Huntington's disease (IsoHD) hum
Externí odkaz:
https://doaj.org/article/f927c3193d514f628e08a8ba49a423df
Publikováno v:
Stem Cell Research, Vol 77, Iss , Pp 103414- (2024)
Late-onset Alzheimer’s disease (AD) has become the paradigm of a non-mendelian complex neurodegenerative disease, for which a major genetic determinant is known, the APOE locus. A rare APOE variant named Christchurch (APOEch) yielding a missense mu
Externí odkaz:
https://doaj.org/article/9dee6022aa0748dea0f8d1731bb99c91
Autor:
Charlotte Gaupp, Benjamin Schmid, Philipp Tripal, Aurélie Edwards, Christoph Daniel, Stefan Zimmermann, Margarete Goppelt-Struebe, Carsten Willam, Seymour Rosen, Gunnar Schley
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Functional and structural alterations of peritubular capillaries (PTCs) are a major determinant of chronic kidney disease (CKD). Using a software-based algorithm for semiautomatic segmentation and morphometric quantification, this study anal
Externí odkaz:
https://doaj.org/article/d556644488c64dfabdd56ca82c5dd2ca
Autor:
Amanda Kongstad Redke Nielsen, Laura Lilieholm-Røngren, Benjamin Schmid, Bjørn Holst, Birger Brodin, Lasse Saaby
Publikováno v:
Stem Cell Research, Vol 76, Iss , Pp 103348- (2024)
The human MDR1 gene encodes the efflux transporter P-glycoprotein, which plays an important part of the blood–brain barrier function of brain microvascular endothelial cells (BMECs). Here, we report the generation of an iPSC line, where a construct
Externí odkaz:
https://doaj.org/article/df09e32efe094dbc9af44f8ef1ddba71
Autor:
Benjamin Schmid, Carla Njeim, Lavanya Vijayasingham, Leah Anku Sanga, Rima Kighsro Naimi, Fouad M. Fouad, Chaza Akik, Carla Zmeter, Sigiriya Aebischer Perone, Lars Bruun Larsen, Jytte Roswall, Éimhín Ansbro, Pablo Perel
Publikováno v:
Journal of Migration and Health, Vol 9, Iss , Pp 100229- (2024)
In line with the peer reviewers comments, the authors have added highlights in stead of an abstract. It was felt that it was better able to capture the findings and is more in line with the paper's target audience.
Externí odkaz:
https://doaj.org/article/cd9e82aeb2314605b199dd44b0647ee8
Autor:
Lavanya Vijayasingham, Éimhín Ansbro, Carla Zmeter, Linda Abou Abbas, Benjamin Schmid, Leah Sanga, Lars Bruun Larsen, Sigiriya Aebischer Perone, Pablo Perel
Publikováno v:
Journal of Migration and Health, Vol 9, Iss , Pp 100228- (2024)
In this commentary, we advocate for the wider implementation of integrated care models for NCDs within humanitarian preparedness, response, and resilience efforts. Since experience and evidence on integrated NCD care in humanitarian settings is limit
Externí odkaz:
https://doaj.org/article/1c11d43f7c8743ec92c89ed3a51798cd
Novel T cell/organoid culture system allows ex vivo modeling of intestinal graft-versus-host disease
Autor:
Diana M. Matthe, Martin Dinkel, Benjamin Schmid, Tina Vogler, Markus F. Neurath, Hendrik Poeck, Clemens Neufert, Maike Büttner-Herold, Kai Hildner
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Acute graft-versus-host disease (GvHD) remains the biggest clinical challenge and prognosis-determining complication after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Donor T cells are acceptedly key mediators of alloreactivity ag
Externí odkaz:
https://doaj.org/article/98fe6b006d434d23960a867290ab3beb
Autor:
Christine Mau, Heike Rudolf, Frederic Strobl, Benjamin Schmid, Timo Regensburger, Ralf Palmisano, Ernst HK Stelzer, Leila Taher, Ezzat El-Sherif
Publikováno v:
eLife, Vol 12 (2023)
A key problem in development is to understand how genes turn on or off at the right place and right time during embryogenesis. Such decisions are made by non-coding sequences called ‘enhancers.’ Much of our models of how enhancers work rely on th
Externí odkaz:
https://doaj.org/article/a8df48fca43b4f279e4bd8e74d54343a
Publikováno v:
Conflict and Health, Vol 16, Iss 1, Pp 1-18 (2022)
Abstract Non-communicable diseases (NCDs) are the leading cause of death and disability globally. Their importance in humanitarian settings is increasingly recognised, but evidence about how best to address NCDs in these setting is limited. This scop
Externí odkaz:
https://doaj.org/article/dbf67438e3da41f789fcbb2a7e705859