Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Benjamin Schinor"'
Autor:
Christian Paul Konken, Bernd Beutel, Benjamin Schinor, Jian Song, Hanna Gerwien, Eva Korpos, Miriam Burmeister, Burkhard Riemann, Michael Schäfers, Lydia Sorokin, Günter Haufe
Publikováno v:
Bioorganic & Medicinal Chemistry. :117350
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df81eef23d1dc73935026e7e9a8d6e32
https://doi.org/10.1016/j.bmc.2023.117350
https://doi.org/10.1016/j.bmc.2023.117350
Autor:
Hanna Gerwien, Christian Paul Konken, Reshma Vidyadharan, Bernd Beutel, Lixia Li, Eva Korpos, Jian Song, Miriam Burmeister, Günter Haufe, Benjamin Schinor, Lydia Sorokin
Publikováno v:
Bioconjugate Chemistry. 29:3715-3725
Matrix metalloproteinases (MMPs) are emerging as pivotal fine-tuners of cell function in tissue homeostasis and in various pathologies, in particular inflammation. In vivo monitoring of the activity of specific MMPs, therefore, provides high potentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b397c372e07f856771968609dd6180a3
https://doi.org/10.1021/acs.bioconjchem.8b00618
https://doi.org/10.1021/acs.bioconjchem.8b00618
Publikováno v:
Journal of Fluorine Chemistry. 203:200-205
The diastereoselectivity of cyclopropanations of styrene and α-fluorostyrene with diazoacetate depends on the catalyst used and the presence or absence of the fluorine substituent. The Cu(acac) 2 catalyzed reaction of styrene with diazoacetate led t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1c54e62cd03fcfc0c8c3a2b20204229
https://doi.org/10.1016/j.jfluchem.2017.09.008
https://doi.org/10.1016/j.jfluchem.2017.09.008
Autor:
Dirk Schepmann, Günter Haufe, Benjamin Schinor, Constantin G. Daniliuc, Svenja Hruschka, Bernhard Wünsch
Publikováno v:
Bioorganic & Medicinal Chemistry. 28:115726
Stereoisomeric 2-aryl-2-fluoro-cyclopropan-1-amines have been discovered as a new class of σ receptor ligands showing different selectivity for the two subtypes of the receptor. Generally, compounds substituted in 4-position are much more active tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5de489955afd488379ad5030c00a230d
https://doi.org/10.1016/j.bmc.2020.115726
https://doi.org/10.1016/j.bmc.2020.115726
Autor:
Maria Teresa Borrello, Benjamin Schinor, Hanae Benelkebir, Graham Packham, Günter Haufe, Katharina Bartels, Leon Douglas, Wafa' T Al-Jamal, A. Ganesan, Patrick J. Duriez, Sara Pereira
Publikováno v:
Bioorganicmedicinal chemistry letters. 27(10)
We report a series of tranylcypromine analogues containing a fluorine in the cyclopropyl ring. A number of compounds with additional m- or p-substitution of the aryl ring were micromolar inhibitors of the LSD1 enzyme. In cellular assays, the compound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a962e5249658b418560b2260d45b071
https://pubmed.ncbi.nlm.nih.gov/28390942
https://pubmed.ncbi.nlm.nih.gov/28390942
Publikováno v:
Journal of Fluorine Chemistry. 155:102-109
Starting from 3- and 4-pentafluorosulfanylbenzaldehydes, a series of cis- and trans-2-aryl-2-fluorocyclopropylamines bearing an SF5 group in 3- or 4-position of the aryl ring were synthesized in 7 steps via the corresponding cyclopropanecarboxylic ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2e9539ef13dffdcc646dd070e65158f
https://doi.org/10.1016/j.jfluchem.2013.07.003
https://doi.org/10.1016/j.jfluchem.2013.07.003