Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Benjamin SaintPierre"'
Autor:
Alexis Boulinguiez, Jamila Dhiab, Barbara Crisol, Laura Muraine, Ludovic Gaut, Corentin Rouxel, Justine Flaire, Hadidja‐Rose Mouigni, Mégane Lemaitre, Benoit Giroux, Lucie Audoux, Benjamin SaintPierre, Arnaud Ferry, Vincent Mouly, Gillian Butler‐Browne, Elisa Negroni, Alberto Malerba, Capucine Trollet
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 5, Pp 1976-1988 (2024)
Abstract Background Exercise is widely considered to have beneficial impact on skeletal muscle aging. In addition, there are also several studies demonstrating a positive effect of exercise on muscular dystrophies. Oculopharyngeal muscular dystrophy
Externí odkaz:
https://doaj.org/article/9e6f075692794eb9b63cdf6993ff5f94
Autor:
Jérémy Amossé, Rima Souki, Maguy El Hajjar, Marie Marques, Valentine Genêt, Alexis Février, Morgane Le Gall, Benjamin SaintPierre, Franck Letourneur, Eric Le Ferrec, Dominique Lagadic-Gossmann, Christine Demeilliers, Lydie Sparfel
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 285, Iss , Pp 117065- (2024)
Exposure to polycyclic aromatic hydrocarbons (PAHs), ubiquitously environmental contaminant, leads to the development of major toxic effects on human health, such as carcinogenic and immunosuppressive alterations reported for the most studied PAH, i.
Externí odkaz:
https://doaj.org/article/1b407791d61841db8c2e4541123ec996
Autor:
Shuaishuai Zhu, Emmanuelle Waeckel-Énée, Masaya Oshima, Anna Moser, Marie-Andrée Bessard, Abdelaziz Gdoura, Kevin Roger, Nina Mode, Joanna Lipecka, Ayse Yilmaz, Barbara Bertocci, Julien Diana, Benjamin Saintpierre, Ida Chiara Guerrera, Raphael Scharfmann, Stefania Francesconi, François-Xavier Mauvais, Peter van Endert
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109929- (2024)
Summary: Tuning of protein homeostasis through mobilization of the unfolded protein response (UPR) is key to the capacity of pancreatic beta cells to cope with variable demand for insulin. Here, we asked how insulin-degrading enzyme (IDE) affects bet
Externí odkaz:
https://doaj.org/article/ef74b2002b644e86886ed16b4a9bb5e4
Autor:
Romain Sanson, Silvia Luna Lazzara, David Cune, Caterina Luana Pitasi, Coralie Trentesaux, Marie Fraudeau, Franck Letourneur, Benjamin Saintpierre, Morgane Le Gall, Pascale Bossard, Benoit Terris, Pascal Finetti, François Bertucci, Emilie Mamessier, Béatrice Romagnolo, Christine Perret
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 3, Pp 689-715 (2023)
Background & Aims: Axin1 is a negative regulator of wingless-type MMTV integration site family, member 1 (Wnt)/β-catenin signaling with tumor-suppressor function. The Wnt pathway has a critical role in the intestine, both during homeostasis and canc
Externí odkaz:
https://doaj.org/article/4a72234f38544a578451fba6ef5a091b
Autor:
Edith Le Floch, Teresa Cosentino, Casper K. Larsen, Felix Beuschlein, Martin Reincke, Laurence Amar, Gian-Paolo Rossi, Kelly De Sousa, Stéphanie Baron, Sophie Chantalat, Benjamin Saintpierre, Livia Lenzini, Arthur Frouin, Isabelle Giscos-Douriez, Matthis Ferey, Alaa B. Abdellatif, Tchao Meatchi, Jean-Philippe Empana, Xavier Jouven, Christian Gieger, Melanie Waldenberger, Annette Peters, Daniele Cusi, Erika Salvi, Pierre Meneton, Mathilde Touvier, Mélanie Deschasaux, Nathalie Druesne-Pecollo, Sheerazed Boulkroun, Fabio L. Fernandes-Rosa, Jean-François Deleuze, Xavier Jeunemaitre, Maria-Christina Zennaro
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Detection of primary aldosteronism, the most common form of secondary arterial hypertension, is essential for targeted management and prevention of cardiovascular complications. Here, the authors identify genetic loci associated with primary aldoster
Externí odkaz:
https://doaj.org/article/b91ee0a8b0104613bac6c910d396b4b9
Autor:
Shahin Tajeri, Laurence Momeux, Benjamin Saintpierre, Sara Mfarrej, Alexander Chapple, Tobias Mourier, Brian Shiels, Frédéric Ariey, Arnab Pain, Gordon Langsley
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract A fungal metabolite, FR235222, specifically inhibits a histone deacetylase of the apicomplexan parasite Toxoplasma gondii and TgHDAC3 has emerged as a key factor regulating developmental stage transition in this species. Here, we exploited F
Externí odkaz:
https://doaj.org/article/b9dd82b8dc624f799c5869c9c2809f6c
Autor:
Quentin Jouhault, Bilade Cherqaoui, Aude Jobart-Malfait, Simon Glatigny, Marc Lauraine, Audrey Hulot, Guillaume Morelle, Benjamin Hagege, Kétia Ermoza, Ahmed El Marjou, Brigitte Izac, Benjamin Saintpierre, Franck Letourneur, Séverine Rémy, Ignacio Anegon, Marie-Christophe Boissier, Gilles Chiocchia, Maxime Breban, Luiza M. Araujo
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
IntroductionSpondylarthritis (SpA) development in HLA-B27/human β2-microglobulin transgenic rat (B27-rat) is correlated with altered conventional dendritic cell (cDC) function that promotes an inflammatory pattern of CD4+T cells, including a biased
Externí odkaz:
https://doaj.org/article/2e30a7f06f474f3182838005f3013d7f
Single-nucleus RNA-seq and FISH identify coordinated transcriptional activity in mammalian myofibers
Autor:
Matthieu Dos Santos, Stéphanie Backer, Benjamin Saintpierre, Brigitte Izac, Muriel Andrieu, Franck Letourneur, Frederic Relaix, Athanassia Sotiropoulos, Pascal Maire
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Whether skeletal muscle fibre gene expression is coordinated as a whole in different nuclei in the fibre is unclear. Here, the authors use single nucleus RNAseq and ATACseq to show the transcriptome heterogeneity of muscle nuclei in the adult mouse f
Externí odkaz:
https://doaj.org/article/8503a3a7129146fea7a01f6be4dfc5d6
Autor:
Erivan, Demanou-Peylin, Sarah, Blanc, Thomas, Da Costa Pereira, Véronique, Parietti, Benjamin, Saintpierre, Franck, Letourneur, Michèle, Souyri, Carine, Domenech
Publikováno v:
Pediatric Research. 91:1064-1068
Autor:
Rima Souki, Jérémy Amosse, Valentine Genêt, Morgane Le Gall, Benjamin Saintpierre, Franck Letourneur, Anne Maître, Christine Demeilliers, Eric Le Ferrec, Dominique Lagadic-Gossmann, Normand Podechard, Lydie Sparfel
Publikováno v:
Environmental Pollution
Environmental Pollution, 2023, 328, pp.121653. ⟨10.1016/j.envpol.2023.121653⟩
Environmental Pollution, 2023, 328, pp.121653. ⟨10.1016/j.envpol.2023.121653⟩
International audience; Polycyclic aromatic hydrocarbons (PAHs) are widely distributed environmental contaminants, triggering deleterious effects such as carcinogenicity and immunosuppression, and peripheral blood mononuclear cells (PBMCs) are among