Výsledky vyhledávání - "Benjamin Randall"

Akademický článek

Independence of a Marine Unicellular Diazotroph to the Presence of NO3−

Autor: Sophie Rabouille, Benjamin Randall, Amélie Talec, Patrick Raimbault, Thierry Blasco, Amel Latifi, Andreas Oschlies

Publikováno v: Microorganisms, Vol 9, Iss 10, p 2073 (2021)

Marine nitrogen (N2) fixation was historically considered to be absent or reduced in nitrate (NO3−) rich environments. This is commonly attributed to the lower energetic cost of NO3− uptake compared to diazotrophy in oxic environments. This parad

Externí odkaz: https://doaj.org/article/dff28fbd1bda45bc99f90df21b4a5a4b

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Akademický článek

Computational modeling of ventricular-ventricular interactions suggest a role in clinical conditions involving heart failure

Autor: Salla M. Kim, E. Benjamin Randall, Filip Jezek, Daniel A. Beard, Naomi C. Chesler

Publikováno v: Frontiers in Physiology, Vol 14 (2023)

Introduction: The left (LV) and right (RV) ventricles are linked biologically, hemodynamically, and mechanically, a phenomenon known as ventricular interdependence. While LV function has long been known to impact RV function, the reverse is increasin

Externí odkaz: https://doaj.org/article/79a7d4ab51be46bd91bb0decbc5d8d94

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Phenotyping heart failure using model-based analysis and physiology-informed machine learning

Autor: Brian E. Carlson, Edith Jones, Daniel A. Beard, Scott L. Hummel, E. Benjamin Randall, David M. Cameron

Publikováno v: J Physiol

To phenotype mechanistic differences between heart failure with reduced (HFrEF) and preserved (HFpEF) ejection fraction, a closed-loop model of the cardiovascular system coupled with patient-specific transthoracic echocardiography (TTE) and right hea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f3378554557d2280e8a64338200116
https://europepmc.org/articles/PMC8595692/

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Independence of a Marine Unicellular Diazotroph to the Presence of NO3−

Autor: Amélie Talec, Sophie Rabouille, Amel Latifi, Andreas Oschlies, Thierry Blasco, Benjamin Randall, Patrick Raimbault

Publikováno v: Microorganisms, Vol 9, Iss 2073, p 2073 (2021)
Microorganisms
Microorganisms, MDPI, 2021, 9 (10), ⟨10.3390/microorganisms9102073⟩
Microorganisms, 2021, 9 (10), pp.2073. ⟨10.3390/microorganisms9102073⟩
Volume 9
Issue 10

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bbc7dba72815c508f0ec280e74d8c6f

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Systems analysis of the mechanisms governing the cardiovascular response to changes in posture and in peripheral demand during exercise

Autor: Filip Jezek, E. Benjamin Randall, Daniel A. Beard, Brian E. Carlson

Publikováno v: Journal of molecular and cellular cardiology. 163

Blood flows and pressures throughout the human cardiovascular system are regulated in response to various dynamic perturbations, such as changes to peripheral demands in exercise, rapid changes in posture, or loss of blood from hemorrhage, via the co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa7dc68e169b8f95f81396f318134f1a
https://pubmed.ncbi.nlm.nih.gov/34626617

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Potential role of intermittent functioning of baroreflexes in the etiology of hypertension in spontaneously hypertensive rats

Autor: Brian E. Carlson, Steven E. Whitesall, Feng Gu, Daniel E. Michele, E. Benjamin Randall, Daniel A. Beard, Gregory D. Fink, Kimber Converso-Baran

Publikováno v: JCI Insight
JCI Insight, Vol 5, Iss 19 (2020)

The spontaneously hypertensive rat (SHR) is a genetic model of primary hypertension with an etiology that includes sympathetic overdrive. To elucidate the neurogenic mechanisms underlying the pathophysiology of this model, we analyzed the dynamic bar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::769c6e33b7c607e36c87862c9f43a242
https://pubmed.ncbi.nlm.nih.gov/33004690

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Global sensitivity analysis informed model reduction and selection applied to a Valsalva maneuver model

Autor: Mette S. Olufsen, Alen Alexanderian, E. Benjamin Randall, Nicholas Z. Randolph

Publikováno v: J Theor Biol

In this study, we develop a methodology for model reduction and selection informed by global sensitivity analysis (GSA) methods. We apply these techniques to a control model that takes systolic blood pressure and thoracic tissue pressure data as inpu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df4678b52a2b86c1406568d35c791015

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Persistent instability in a nonhomogeneous delay differential equation system of the Valsalva maneuver

Autor: E. Benjamin Randall, Nicholas Z. Randolph, Mette S. Olufsen

Delay differential equations (DDEs) are widely used in mathematical modeling to describe physical and biological systems. Delays can impact model dynamics, resulting in oscillatory behavior. In physiological systems, this instability may signify (i)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a0c6f421dcb77f47c015eb96f3a516e
http://arxiv.org/abs/1908.09371

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A model-based analysis of autonomic nervous function in response to the Valsalva maneuver

Autor: Mette S. Olufsen, Anna Billeschou, Louise Brinth, E. Benjamin Randall, Jesper Mehlsen

Publikováno v: J Appl Physiol (1985)

The Valsalva maneuver (VM) is a diagnostic protocol examining sympathetic and parasympathetic activity in patients with autonomic dysfunction (AD) impacting cardiovascular control. Because direct measurement of these signals is costly and invasive, A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd205b3a8cba6f56c3276b5f474ab32f
https://pubmed.ncbi.nlm.nih.gov/31369335

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