Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Benjamin R. P. Stone"'
Autor:
Pingli Liu, James P. Sherbine, Patrick J. Sheeran, Stephen R. Anderson, Benjamin R. P. Stone, Jiang Zhu, Subodh Shrinivas Deshmukh, James J. Haley, Nicholas A. Magnus, Lindsay A. Hobson, William A. Nugent
Publikováno v:
Organic Process Research & Development. 11:985-995
This report describes the large-scale synthesis of 1 that features a Fischer indole strategy to form an advanced intermediate followed by reduction to the indoline to construct the tetracyclic core of the molecule. Resolution using dibenzoyl-d-tartar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::393af969ac69807fc8425c2d159826f9
https://doi.org/10.1021/op700121y
https://doi.org/10.1021/op700121y
Autor:
Benjamin R. P. Stone, Mona Patel, Ronald M Klabe, Sena Garber, Lee T Bacheler, Matthew R. Wright, Kelly Logue, Beverly C Cordova, Susan Erickson-Viitanen, Robert F. Kaltenbach, Gregory D. Harris, Robert E. Waltermire, George L. Trainor
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 13:605-608
A series of P1/P1' substituted cyclic urea analogues were prepared in an attempt to increase the intra-cellular antiviral potency of the nonsymmetrical 3-aminoindazoles DMP 850 and DMP 851. The effect of alkyl substitution of the P1/P1' residues on c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a4872e3906a4cddc7312923b3d6bf27
https://doi.org/10.1016/s0960-894x(02)01064-8
https://doi.org/10.1016/s0960-894x(02)01064-8
Autor:
Pat N. Confalone, Thomas E. Smyser, Benjamin R. P. Stone, Reginald O. Cann, Gregory D. Harris
Publikováno v:
Tetrahedron Letters. 39:6127-6130
Unsymmetric cyclic urea diols of general structure 1 can be prepared either via an isourea derived from the symmetric diamine 2 or by the selective removal of a benzyl group from certain symmetric cyclic ureas 8, employing dissolving metal reduction.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34737a802161d58c5301174123a4bc0f
https://doi.org/10.1016/s0040-4039(98)01263-5
https://doi.org/10.1016/s0040-4039(98)01263-5
Autor:
Gregory D. Harris, Thomas E. Smyser, Pat N. Confalone, Reginald O. Cann, Benjamin R. P. Stone
Publikováno v:
ChemInform. 29
Unsymmetric cyclic urea diols of general structure 1 can be prepared either via an isourea derived from the symmetric diamine 2 or by the selective removal of a benzyl group from certain symmetric cyclic ureas 8, employing dissolving metal reduction.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56fcfa7946c863c9b1a83b99a686cca3
https://doi.org/10.1002/chin.199845170
https://doi.org/10.1002/chin.199845170
Autor:
Gregory D. Harris, Benjamin R. P. Stone, R. L. Dorow, Nicholas A. Magnus, Pesti Jaan A, Pat N. Confalone, William A. Nugent, Joseph M. Fortunak, Rodney L. Parsons, Goss S. Kauffman
Publikováno v:
Organic Letters. 2:3119-3121
The beta-amino alcohol 4 beta-morpholinocaran-3 alpha-ol is prepared by addition of morpholine to alpha-3,4-epoxycarane utilizing anhydrous magnesium bromide as Lewis acid promoter. The enantiopure amino alcohol is uniquely effective as a chiral mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec2e68e61a4c9da9c57fe67b8aacc6f6
https://doi.org/10.1021/ol006321x
https://doi.org/10.1021/ol006321x
Autor:
William A. Nugent, Gregory D. Harris, Benjamin R. P. Stone, Nicholas A. Magnus, Pat N. Confalone, Pesti Jaan A, Joseph M. Fortunak, R. L. Dorow, Rodney L. Parsons, Goss S. Kauffman
Publikováno v:
ChemInform. 32
The beta-amino alcohol 4 beta-morpholinocaran-3 alpha-ol is prepared by addition of morpholine to alpha-3,4-epoxycarane utilizing anhydrous magnesium bromide as Lewis acid promoter. The enantiopure amino alcohol is uniquely effective as a chiral mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f281f0ecd3032465a925c8dc6f0d08fd
https://doi.org/10.1002/chin.200106132
https://doi.org/10.1002/chin.200106132
Autor:
Lindsay A. Hobson, William A. Nugent, Stephen R. Anderson, Subodh S. Deshmukh, James J. Haley III, Pingli Liu, Nicholas A. Magnus, Patrick Sheeran, James P. Sherbine, Benjamin R. P. Stone, Jiang Zhu
Publikováno v:
Organic Process Research & Development; Oct2007, Vol. 11 Issue 6, p985-995, 11p