Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Benjamin R. Doughty"'
Autor:
Drew T. Bergman, Philine Guckelberger, Eric S. Lander, Jesse M. Engreitz, Qingbo Wang, Vidya Subramanian, Anna Greka, Linlin M. Chen, Benjamin R. Doughty, Joseph Nasser, Sarah Mangiameli, Jamie L. Marshall, Teia Noel, K. Zhang, Fei Chen, Charles P. Fulco, Elizabeth J. Grinkevich, Samuel G. Rodriques
Publikováno v:
Proc Natl Acad Sci U S A
Single-cell quantification of RNAs is important for understanding cellular heterogeneity and gene regulation, yet current approaches suffer from low sensitivity for individual transcripts, limiting their utility for many applications. Here we present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c98335d6e937cf414fc0f905dac00c0
https://doi.org/10.1073/pnas.2010738117
https://doi.org/10.1073/pnas.2010738117
Autor:
Tejal A. Patwardhan, Fritz Lekschas, Jesse M. Engreitz, Alkes L. Price, Hanspeter Pfister, Mark J. Daly, Glen Munson, Michael Kane, Jacob C. Ulirsch, Helen Y. Kang, Nir Hacohen, Ramnik J. Xavier, Anshul Kundaje, Heini M. Natri, Elle M. Weeks, Tung T. Nguyen, Drew T. Bergman, Benjamin R. Doughty, Thouis R. Jones, Eric S. Lander, Joseph Nasser, Kristy Mualim, Thomas Eisenhaure, Ryan L. Collins, Philine Guckelberger, Kushal K. Dey, John P. Ray, Ang Cui, Hilary K. Finucane, Charles P. Fulco, Hailiang Huang, Charles B. Epstein
Publikováno v:
Nature
Genome-wide association studies (GWAS) have identified thousands of noncoding loci that are associated with human diseases and complex traits, each of which could reveal insights into the mechanisms of disease1. Many of the underlying causal variants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67d0ccb04cb7636886b8aa9ef621df7d
https://europepmc.org/articles/PMC9153265/
https://europepmc.org/articles/PMC9153265/
Autor:
Tejal A. Patwardhan, Tom M. Eisenhaure, Benjamin R. Doughty, Jacob C. Ulirsch, Thouis R. Jones, Tung T. Nguyen, Michael Kane, Kushal K. Dey, Helen Y. Kang, Philine Guckelberger, Mark J. Daly, Elle M. Weeks, Joseph Nasser, Drew T. Bergman, Anshul Kundaje, Jesse M. Engreitz, Ang Cui, Hilary K. Finucane, Alkes L. Price, Glen Munson, John P. Ray, Nir Hacohen, Kristy Mualim, Eric S. Lander, Heini M. Natri, Charles B. Epstein, Ramnik J. Xavier, Charles P. Fulco, Hailiang Huang, Ryan L. Collins
Genome-wide association studies have now identified tens of thousands of noncoding loci associated with human diseases and complex traits, each of which could reveal insights into biological mechanisms of disease. Many of the underlying causal varian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af602c085e001e44d42cac6b461e53ec
https://doi.org/10.1101/2020.09.01.278093
https://doi.org/10.1101/2020.09.01.278093
Autor:
Joseph Nasser, Linlin M. Chen, Qingbo Wang, Benjamin R. Doughty, Jamie L. Marshall, Samuel G. Rodriques, Teia Noel, Sarah Mangiameli, Jesse M. Engreitz, Eric S. Lander, Anna Greka, Vidya Subramanian, Fei Chen, Philine Guckelberger, Elizabeth J. Grinkevich, Charles P. Fulco, K. Zhang
Single-cell quantification of RNAs is important for understanding cellular heterogeneity and gene regulation, yet current approaches suffer from low sensitivity for individual transcripts, limiting their utility for many applications. Here we present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6890896c2afd13aa2b5a73ac24e79cd4
https://doi.org/10.1101/2020.06.01.128314
https://doi.org/10.1101/2020.06.01.128314
Autor:
Sharon R. Grossman, Glen Munson, Joseph Nasser, Drew T. Bergman, Elizabeth M. Perez, Michael Kane, Elena K. Stamenova, Benjamin R. Doughty, Thouis R. Jones, Charles P. Fulco, Rockwell Anyoha, Eric S. Lander, Neva C. Durand, Tung T. Nguyen, Tejal A. Patwardhan, Vidya Subramanian, Jesse M. Engreitz, Erez Lieberman Aiden
Mammalian genomes harbor millions of noncoding elements called enhancers that quantitatively regulate gene expression, but it remains unclear which enhancers regulate which genes. Here we describe an experimental approach, based on CRISPR interferenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62a9c53caf034ef390045c07f233f26d
https://doi.org/10.1101/529990
https://doi.org/10.1101/529990
Autor:
Sharon R. Grossman, Glen Munson, Charles P. Fulco, Thouis R. Jones, Tejal A. Patwardhan, Caleb A. Lareau, Drew T. Bergman, Jesse M. Engreitz, Vidya Subramanian, Elena K. Stamenova, Rockwell Anyoha, Benjamin R. Doughty, Elizabeth M. Perez, Erez Lieberman Aiden, Michael Kane, Eric S. Lander, Joseph Nasser, Tung T. Nguyen, Neva C. Durand
Publikováno v:
Nature genetics
Enhancer elements in the human genome control how genes are expressed in specific cell types and harbor thousands of genetic variants that influence risk for common diseases1-4. Yet, we still do not know how enhancers regulate specific genes, and we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e6989fecb3145849ffe92cac2428a3c
https://pubmed.ncbi.nlm.nih.gov/31784730
https://pubmed.ncbi.nlm.nih.gov/31784730