Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Benjamin R. Coyac"'
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Medication-related osteonecrosis of the jaw is a serious complication that develops in oncologic patients treated with Zoledronic acid. Although used for over 30 years, the influence of Zoledronic acid on bone has been thoroughly investig
Externí odkaz:
https://doaj.org/article/e3dec52068c64b4d80fd96e190e7502c
Autor:
Benjamin R. Coyac, Laurent Detzen, Philippe Doucet, Brigitte Baroukh, Annie Llorens, Martine Bonnaure-Mallet, Marjolaine Gosset, Denis Barritault, Marie-Laure Colombier, Jean-Louis Saffar
Publikováno v:
Heliyon, Vol 4, Iss 8, Pp e00719- (2018)
Background: Periodontitis is a set of chronic inflammatory diseases affecting the supporting structures of the teeth, during which a persistent release of lytic enzymes and inflammatory mediators causes a self-perpetuating vicious cycle of tissue des
Externí odkaz:
https://doaj.org/article/d697b3af935e4a2da84288209aebdd03
Autor:
Benjamin R. Coyac, Benjamin J. Wolf, Daniel J. Bahat, Masaki Arioka, John B. Brunski, Jill A. Helms
Publikováno v:
Journal of Clinical Periodontology. 49:782-798
Autologous bone grafts consolidate faster than bone graft substitutes (BGSs) but resorb over time, which compromises implant support. We hypothesized that differences in consolidation rates affected the mechanical properties of grafts and implant sta
Autor:
Ofri Doppelt-Flikshtain, Amin Younis, Tal Tamari, Ofir Ginesin, Talia Shentzer-Kutiel, David Nikomarov, Gil Bar-Sela, Benjamin R. Coyac, Yehuda G. Assaraf, Hadar Zigdon-Giladi
Publikováno v:
Cancers; Volume 15; Issue 6; Pages: 1818
Background: Osteosarcoma (OS) mortality is attributed to lung metastases. Endothelial progenitor cells (EPCs) mediate the angiogenic switch in several cancers. The spatial proximity between EPCs and OS in the bone led to the hypothesis that EPCs-oste
Autor:
Igor Pilawski, Xue Yuan, Pavla Ticha, U.S. Tulu, Benjamin R. Coyac, Jill A. Helms, Jie Pan, Waldemar Hoffmann
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
The disconnect between preclinical and clinical results underscores the imperative for establishing good animal models, then gleaning all available data on efficacy, safety, and potential toxicities associated with a device or drug. Mini pigs are a c
Autor:
Waldemar Hoffmann, Zhijun Li, Benjamin R. Coyac, Brian Leahy, Giuseppe Salvi, Jill A. Helms, Benjamin Salmon
Publikováno v:
Journal of Periodontology. 92:716-726
Background Bone debris generated during site preparation is generally evacuated with irrigation; here, we evaluated whether retention of this autologous material improved the rate of peri‐implant bone formation. Materials and methods In 25 rats, a
Autor:
Jill A. Helms, Benjamin R. Coyac, Brian Leahy, John B. Brunski, Qiang Sun, Giuseppe Salvi, Xue Yuan
Publikováno v:
J Periodontol
Background Autologous bone can be harvested from the flutes of a conventional drill or from a bone scraper; here we compared whether autologous bone chips generated by a new slow-speed instrument were more osteogenic than the bone chips generated by
Autor:
Benjamin Salmon, Claire Bardet, Mayssam Khaddam, Jiar Naji, Benjamin R Coyac, Brigitte Baroukh, Franck Letourneur, Julie Lesieur, Franck Decup, Dominique Le Denmat, Antonino Nicoletti, Anne Poliard, Peter S Rowe, Eric Huet, Sibylle Opsahl Vital, Agnès Linglart, Marc D McKee, Catherine Chaussain
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56749 (2013)
Mutations in PHEX (phosphate-regulating gene with homologies to endopeptidases on the X-chromosome) cause X-linked familial hypophosphatemic rickets (XLH), a disorder having severe bone and tooth dentin mineralization defects. The absence of function
Externí odkaz:
https://doaj.org/article/820187aed9344615a2c61876bf69651a
Autor:
Catherine Chaussain, Thorsten Schinke, Agnès Linglart, Marc D. McKee, Alain Schmitt, Claire Bardet, Guillaume Penel, Guillaume Falgayrac, Benjamin R. Coyac
Publikováno v:
Connective Tissue Research. 59:91-96
X-linked hypophosphatemia (XLH) is a skeletal disorder arising from mutations in the PHEX gene, transmitted in most cases as an X-linked dominant trait. PHEX deficiency leads to renal phosphate wasting and hypophosphatemia, as well as impaired minera
Autor:
Benjamin R. Coyac, Giuseppe Salvi, Waldemar Hoffmann, Jill A. Helms, Brian Leahy, John B. Brunski
Publikováno v:
Clinical oral implants researchREFERENCES. 30(12)
Objective Primary stability is a prerequisite for implant osseointegration. Some degree of misfit between an implant and its osteotomy is required to ensure primary stability, and this is typically achieved by undersizing an implant osteotomy. In thi