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of 8
pro vyhledávání: '"Benjamin R. Cassidy"'
Autor:
Benjamin R. Cassidy, Sreemathi Logan, Julie A. Farley, Daniel B. Owen, William E. Sonntag, Douglas A. Drevets
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundNeuro-cognitive impairment is a deleterious complication of bacterial infections that is difficult to treat or prevent. Listeria monocytogenes (Lm) is a neuroinvasive bacterial pathogen and commonly used model organism for studying immune r
Externí odkaz:
https://doaj.org/article/3fe99d3a64dc419babc6d095e10b4edc
Autor:
Benjamin R. Cassidy, Sreemathi Logan, Julie Farley, Daniel Owen, William E. Sonntag, Douglas A. Drevets
Publikováno v:
Journal of Affective Disorders Reports, Vol 12, Iss , Pp 100536- (2023)
Background: Leukocytes recruited into the central nervous system after infection help clear pathogens and provide long-lasting immune surveillance, but also can contribute to harmful post-infectious neuroinflammation. Listeria monocytogenes (Lm) is a
Externí odkaz:
https://doaj.org/article/73b569590005497b97fb745142124d06
Publikováno v:
Immunity & Ageing, Vol 19, Iss 1, Pp 1-18 (2022)
Abstract Background Understanding mechanisms of pathologic neuroinflammation is essential for improving outcomes after central nervous system infections. Brain tissue-resident memory T cells (bTRM) are recruited during central nervous system infectio
Externí odkaz:
https://doaj.org/article/ae52d52203f944d3bcff3f4ccf028ed0
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-15 (2020)
Abstract Background Brain inflammation is a key cause of cognitive decline after central nervous system (CNS) infections. A thorough understanding of immune responses to CNS infection is essential for developing anti-inflammatory interventions that i
Externí odkaz:
https://doaj.org/article/589d7a508daa462bafcfa9a226da46c2
Autor:
Tamas Csipo, Benjamin R. Cassidy, Priya Balasubramanian, Douglas A. Drevets, Zoltan I. Ungvari, Andriy Yabluchanskiy
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Sepsis is a life-threatening condition, the incidence of which is significantly increased in elderly patients. One of the long-lasting effects of sepsis is cognitive impairment defined as a new deficit or exacerbation of preexisting deficits in globa
Externí odkaz:
https://doaj.org/article/d4187f8643c54b92bf363861f0e212b8
Autor:
Miao Zhang, Allison. F. Gillaspy, Jenny R. Gipson, Benjamin R. Cassidy, Jessica L. Nave, Misty F. Brewer, Julie A. Stoner, Jie Chen, Douglas A. Drevets
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
MicroRNA (miR) miR-155 modulates microglial activation and polarization, but its role in activation of microglia during bacterial brain infection is unclear. We studied miR-155 expression in brains of C57BL/6 (B6.WT) mice infected i.p. with the neuro
Externí odkaz:
https://doaj.org/article/cd69d1f524144bad981d452131a739ad
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-15 (2020)
BackgroundBrain inflammation is a key cause of cognitive decline after central nervous system (CNS) infections. A thorough understanding of immune responses to CNS infection is essential for developing anti-inflammatory interventions that improve out
Anionic phospholipid expression as a molecular target in Listeria monocytogenes and Escherichia coli
Autor:
Alexis Woodward, Roger G. Harrison, James Battiste, Patrick McKernan, Douglas A. Drevets, Benjamin R. Cassidy
Publikováno v:
International journal of antimicrobial agents. 56(6)
This study validates bacterial anionic phospholipids (APs) as a putative molecular target in a novel antibiotic treatment against the Gram-positive bacterium Listeria monocytogenes and the Gram-negative bacterium Escherichia coli. Bacterial AP expres