Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Benjamin R Troutwine"'
Autor:
Kaitlin Flannagan, Julia A. Stopperan, Brittany M. Hauger, Benjamin R. Troutwine, Colton R. Lysaker, Taylor A. Strope, Vivien Csikos Drummond, Caleb A. Gilmore, Natalie A. Swerdlow, Julia M. Draper, Cynthia M. Gouvion, Jay L. Vivian, Mohammad Haeri, Russell H. Swerdlow, Heather M. Wilkins
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
IntroductionMitochondrial dysfunction is observed in Alzheimer’s disease (AD). Altered mitochondrial respiration, cytochrome oxidase (COX) Vmax, and mitophagy are observed in human subjects and animal models of AD. Models derived from induced pluri
Externí odkaz:
https://doaj.org/article/127198d0d9af4585a86ea509bb550673
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 2, Pp 496-510 (2022)
Genetic variation in apolipoprotein E (APOE) influences Alzheimer's disease (AD) risk. APOE ε4 alleles are the strongest genetic risk factor for late onset sporadic AD. The AD risk is dose dependent, as those carrying one APOE ε4 allele have a 2–
Externí odkaz:
https://doaj.org/article/c613d0afe542406d814cd27e0b00d475
Autor:
Benjamin R. Troutwine, Taylor A. Strope, Edziu Franczak, Colton R. Lysaker, Laylan Hamid, Clayton Mansel, Julia A. Stopperan, Cynthia M. Gouvion, Mohammad Haeri, Russell H. Swerdlow, Heather M. Wilkins
Publikováno v:
Neurobiology of Disease, Vol 171, Iss , Pp 105781- (2022)
Introduction: Mitochondrial dysfunction is observed in Alzheimer's disease (AD). However, the relationship between functional mitochondrial deficits and AD pathologies is not well established in human subjects. Methods: Post-mortem human brain tissue
Externí odkaz:
https://doaj.org/article/582d0d131aae48a1957bd062e00a2945
Autor:
Yunjia Wang, Zhenhao Liu, Guanteng Yang, Qile Gao, Lige Xiao, Jiong Li, Chaofeng Guo, Benjamin R. Troutwine, Ryan S. Gray, Lu Xie, Hongqi Zhang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Adolescent idiopathic scoliosis (AIS) is the most common pediatric spine disorder affecting ∼3% of children worldwide. Human genetic studies suggest a complex polygenic disease model for AIS with large genetic and phenotypic heterogeneity. However,
Externí odkaz:
https://doaj.org/article/70830f076ec64305bb420f9c14282006
Publikováno v:
Dev Biol
Adolescent idiopathic scoliosis (AIS) is a common pediatric musculoskeletal disorder worldwide, characterized by atypical spine curvatures in otherwise healthy children. Human genetic studies have identified candidate genes associated with AIS, howev
Autor:
Taylor A. Strope, Russell H. Swerdlow, Blaise W. Menta, Colton R. Lysaker, Benjamin R. Troutwine, Heather M. Wilkins, Sharon Manley
Publikováno v:
Journal of Alzheimer's Disease. 85:381-394
Background: Amyloid-β (Aβ), which derives from the amyloid-β protein precursor (AβPP), forms plaques and serves as a fluid biomarker in Alzheimer’s disease (AD). How Aβ forms from AβPP is known, but questions relating to AβPP and Aβ biology
Autor:
Benjamin R Troutwine, Colton R Lysaker, Taylor A. Strope, Russell H Swerdlow, Heather M Wilkins
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Benjamin R Troutwine, Ian Weidling, Casey S. John, Zachary D. Green, Paul J. Kueck, Russell H Swerdlow, Heather M Wilkins, Jill K. Morris
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Colton R Lysaker, Benjamin R Troutwine, Taylor A. Strope, Edziu M Franczak, Julie A Allen, Munish Chauhan, Janna L Harris, John P Thyfault, Heather M Wilkins
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Kaitlin Flannagan, Julia A. Stopperan, Benjamin R Troutwine, Colton R Lysaker, Taylor A. Strope, Julia Draper, Cynthia Shaddy‐Gouvion, Jay Vivian, Mohammad Haeri, Heather M Wilkins
Publikováno v:
Alzheimer's & Dementia. 17