Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Benjamin R E Harris"'
Autor:
Margot P. Cleary, Xiaoqian Zhao, Benjamin R E Harris, Jianxin Tao, Da-Qing Yang, Renhui Shen, Tong Wang, Ye Zhang
Publikováno v:
The FASEB Journal. 35
Enhanced glucose uptake is coupled with elevated aerobic glycolysis (the Warburg effect) in cancer cells and is closely correlated with increased tumor aggressiveness and poor prognosis. We previously discovered that ATM, a protein kinase deficient i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59b656ca079c724990880a7d99b2b0c4
https://doi.org/10.1096/fj.202001415rr
https://doi.org/10.1096/fj.202001415rr
Autor:
Margot P. Cleary, Aniekan Okon, Marina G. Ferrari, Ye Zhang, Da-Qing Yang, Carston R. Wagner, Defeng Wang, Benjamin R E Harris
Publikováno v:
Molecular and Cellular Biology. 38
The p53 tumor suppressor plays a critical role in protecting normal cells from malignant transformation. Development of small molecules to reactivate p53 in cancer cells has been an area of intense research. We previously identified an internal ribos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::684a0f63a66ec4653c1a3ffdb83610cf
https://doi.org/10.1128/mcb.00367-17
https://doi.org/10.1128/mcb.00367-17
Publikováno v:
Molecular and Cellular Biology. 35:4006-4017
Synthesis of the p53 tumor suppressor and its subsequent activation following DNA damage are critical for its protection against tumorigenesis. We previously discovered an internal ribosome entry site (IRES) at the 5' untranslated region of the p53 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d974b37bbb2dcf0794495dafb9081d2
https://doi.org/10.1128/mcb.00365-15
https://doi.org/10.1128/mcb.00365-15
Autor:
Jianhua Liu, Margot P. Cleary, Benjamin R E Harris, Sergio A. Gradilone, Da-Qing Yang, Yibin Deng, Bai Ji, Yahui Liu
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 18, Iss 1, p 93 (2017)
International Journal of Molecular Sciences, Vol 18, Iss 1, p 93 (2017)
While translational regulation of p53 by the internal ribosome entry site (IRES) at its 5'-untranslated region following DNA damage has been widely accepted, the detailed mechanism underlying the translational control of p53 by its IRES sequence is s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f19657456b378ab0e8adf6d2d662a063
http://europepmc.org/articles/PMC5297727
http://europepmc.org/articles/PMC5297727
Autor:
Margot P. Cleary, Adrian D. Hegeman, Da Qing Yang, Dana M. Freund, Defeng Wang, Benjamin R E Harris
The ability of cancer cells to produce lactate through aerobic glycolysis is a hallmark of cancer. In this study, we established a positional isotopic labeling and LC-MS-based method that can specifically measure the conversion of glucose to lactate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caf6558e705a1075a04915c98a890c34
https://europepmc.org/articles/PMC5039094/
https://europepmc.org/articles/PMC5039094/
Autor:
Margot P. Cleary, Adrian D. Hegeman, S Jiang, Yingming Li, Benjamin R E Harris, D-Q Yang, Dana M. Freund
Publikováno v:
Cancer Research. 76:P5-05
The ability of cancer cells to produce large amounts of lactate through aerobic glycosis (Warburg effect) is coupled to high rates of glucose uptake. Enhanced glucose uptake and glycolysis are closely correlated to increased breast tumor aggressivene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87b220957cf1dcffe34933d98d26d3f8
https://doi.org/10.1158/1538-7445.sabcs15-p5-05-05
https://doi.org/10.1158/1538-7445.sabcs15-p5-05-05