Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Benjamin R, Brooks"'
Autor:
Jeremy M, Shefner, Jinsy A, Andrews, Angela, Genge, Carlayne, Jackson, Noah, Lechtzin, Timothy M, Miller, Bettina M, Cockroft, Lisa, Meng, Jenny, Wei, Andrew A, Wolff, Fady I, Malik, Cynthia, Bodkin, Benjamin R, Brooks, James, Caress, Annie, Dionne, Dominic, Fee, Stephen A, Goutman, Namita A, Goyal, Orla, Hardiman, Ghazala, Hayat, Terry, Heiman-Patterson, Daragh, Heitzman, Robert D, Henderson, Wendy, Johnston, Chafic, Karam, Matthew C, Kiernan, Stephen J, Kolb, Lawrence, Korngut, Shafeeq, Ladha, Genevieve, Matte, Jesus S, Mora, Merrilee, Needham, Bjorn, Oskarsson, Gary L, Pattee, Erik P, Pioro, Michael, Pulley, Dianna, Quan, Kourosh, Rezania, Kerri L, Schellenberg, David, Schultz, Christen, Shoesmith, Zachary, Simmons, Jeffrey, Statland, Shumaila, Sultan, Andrea, Swenson, Leonard H Van Den, Berg, Tuan, Vu, Steve, Vucic, Michael, Weiss, Ashley, Whyte-Rayson, James, Wymer, Lorne, Zinman, Stacy A, Rudnicki
Publikováno v:
Amyotrophic lateral sclerosis & frontotemporal degeneration
Objective: To evaluate safety, dose response, and preliminary efficacy of reldesemtiv over 12 weeks in patients with amyotrophic lateral sclerosis (ALS). Methods: Patients (≤2 years since diagnosis) with slow upright vital capacity (SVC) of ≥60%
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ecaeaa5a40cd6b69dedae5d239784f79
https://pubmed.ncbi.nlm.nih.gov/32969758
https://pubmed.ncbi.nlm.nih.gov/32969758
Autor:
Benjamin R Brooks, Andrew Eisen, Gilbert Bensimon, Wim Robberecht, Vincent Meininger, P. Nigel Leigh, Patrice Douillet, Lucette Lacomblez, Walter G. Bradley
Publikováno v:
Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders. 5:107-117
Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive and fatal motor neuron disease. We carried out two randomized, double-blind, placebo-controlled, multi-centre, multi-national studies with xaliproden (a drug with neurotrophic effect)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a85ad521f8d1069a7258304d0820ee59
https://doi.org/10.1080/14660820410019602
https://doi.org/10.1080/14660820410019602
A longitudinal study of motor performance and striatal [18F]fluorodopa uptake in Parkinson's disease
Autor:
Sterling C. Johnson, Catherine L. Gallagher, Moo K. Chung, Richard Konopacki, Barbara B. Bendlin, James H. Abbs, Benjamin R. Brooks, Onofre T. DeJesus, James E. Holden, Terrence R. Oakes, Guofan Xu, Selami Dogan, Robert J. Nickles, Robert W. Pyzalski, W. Douglas Brown
Although [(18)F]fluoro-L: -dopa [FDOPA] positron emission tomography (PET) has been used as a surrogate outcome measure in Parkinson's disease therapeutic trials, this biomarker has not been proven to reflect clinical status longitudinally. We comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ebc1d339f83bbf6a120864e6911f415
https://europepmc.org/articles/PMC3150388/
https://europepmc.org/articles/PMC3150388/
The ts1 mutant of Moloney murine leukemia virus TB causes degenerative neurologic and immunologic disease in mice, characterized by development of spongiform encephalomyelopathy resulting in hindlimb paralysis, marked thymic atrophy associated with i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e03230a14f3c1d14a8a9fa0d8a3233e4
https://europepmc.org/articles/PMC52637/
https://europepmc.org/articles/PMC52637/
Autor:
John F. Tallman, Daniel P. van Kammen, Gerald L. Brown, Benjamin R. Brooks, David C. Jimerson, Robert M. Post, Craig C. Smith, William E. Bunney
Publikováno v:
Life Sciences. 19:131-136
Baseline c-AMP levels, and probenecid-induced accumulations of c-AMP and c-GMP in the lumbar CSF of depressed, manic, and schizophrenic patients failed to show differences when compared to controls screened to exclude affective, schizophrenic, and CN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6170c303f0a5900026c80378547ac6de
https://doi.org/10.1016/0024-3205(76)90383-0
https://doi.org/10.1016/0024-3205(76)90383-0
Publikováno v:
Annual Review of Neuroscience. 2:309-340
Slow viral infections of the central nervous system (CNS) are dependent not only on the unique biological properties of viruses, but also on the properties of the neural cells that they infect and on the response of the host to that infection (Johnso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d623c45d37060cb29946397a8a2db74
https://doi.org/10.1146/annurev.ne.02.030179.001521
https://doi.org/10.1146/annurev.ne.02.030179.001521
Publikováno v:
Neuropathology and Applied Neurobiology. 7:365-380
Swarz J.R., Brooks B.R. & Johnson R.T. (1981) Neuropathology and Applied Neurobiology 7, 365–380 Spongiform polioencephalomyelopathy caused by a murine retrovirus. II. Ultrastructural localization of virus replication and spongiform changes in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fc8f0a7ce8eaacb3533b5c6de29a99f
https://doi.org/10.1111/j.1365-2990.1981.tb00239.x
https://doi.org/10.1111/j.1365-2990.1981.tb00239.x
Autor:
Benjamin R. Brooks, Robert L. Hirsch, Foroozan Mokhtarian, Diane E. Griffin, Richard T. Johnson, Jay L. Hess
Publikováno v:
Clinical Immunology and Immunopathology. 21:341-350
Measles virus vaccination of adults seropositive for measles resulted in suppression of chemotactic factor production in response to concanavalin A (Con A), purified protein derivative (PPD), and purified measles virus antigen, and of lymphoprolifera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e10cc9d43b5c4a8b1319d57f9f77320c
https://doi.org/10.1016/0090-1229(81)90223-3
https://doi.org/10.1016/0090-1229(81)90223-3
Autor:
Richard T. Johnson, Steven R. Cohen, Robert L. Hirsch, Benjamin R. Brooks, P. K. Coyle, Patricia O'Donnell, Jerry S. Wolinsky
Publikováno v:
The Lancet. 316:229-232
A specific subpopulation of mononuclear cells bearing a surface receptor for the Fc portion of IgG was considerably reduced in the cerebrospinal fluid (CSF) of multiple sclerosis (MS) patients during exacerbation, but returned toward normal levels as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3a9d53fdbfe7bdb0f80db2611b4f9dc
https://doi.org/10.1016/s0140-6736(80)90121-x
https://doi.org/10.1016/s0140-6736(80)90121-x
Autor:
James C. Ballenger, Benjamin R. Brooks, Robert M. Post, Theodore A. Hare, Bruce S. Glaeser, James H. Wood
Publikováno v:
Brain Research Bulletin. 5:747-753
GABA has been implicated in the neurochemistry of epilepsy. The mean lumbar CSF GABA concentration determined by ion-exchange/fluorometric assay among 21 medicated patients with intractable seizures was significantly lower (p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba844bb9e2562cf4d8b828e5e64f44a0
https://doi.org/10.1016/0361-9230(80)90123-9
https://doi.org/10.1016/0361-9230(80)90123-9