Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Benjamin Podbilewicz"'
Publikováno v:
STAR Protocols, Vol 5, Iss 2, Pp 103063- (2024)
Summary: Studying neuronal morphology requires imaging and accurate extraction of tree-like shapes from noisy microscopy data. Here, we present a protocol for automatic reconstruction of branched structures from microscopy images using Neuronalyzer s
Externí odkaz:
https://doaj.org/article/6a0a860c88944efb8c0a0f628b2a4f99
Publikováno v:
eLife, Vol 13 (2024)
The fusion of mammalian gametes requires the interaction between IZUMO1 on the sperm and JUNO on the oocyte. We have recently shown that ectopic expression of mouse IZUMO1 induces cell-cell fusion and that sperm can fuse to fibroblasts expressing JUN
Externí odkaz:
https://doaj.org/article/96224c3a73184e5497af9447dde3beca
Autor:
David Moi, Shunsuke Nishio, Xiaohui Li, Clari Valansi, Mauricio Langleib, Nicolas G. Brukman, Kateryna Flyak, Christophe Dessimoz, Daniele de Sanctis, Kathryn Tunyasuvunakool, John Jumper, Martin Graña, Héctor Romero, Pablo S. Aguilar, Luca Jovine, Benjamin Podbilewicz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Sexual reproduction in eukaryotes involves gamete fusion, mediated by fusogenic proteins. Here, the authors identify fusogenic protein homologs encoded within mobile genetic elements in archaeal genomes, solve the crystal structure of one of the prot
Externí odkaz:
https://doaj.org/article/e91bd8b053f6444b80b6f8d4bed3bed4
Autor:
Kohdai P. Nakajima, Clari Valansi, Daisuke Kurihara, Narie Sasaki, Benjamin Podbilewicz, Tetsuya Higashiyama
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Successful gamete fusion requires species-specific membrane adhesion. However, the interaction of adhesion molecules in gametes is difficult to study in real time through low-throughput microscopic observation. Therefore, we developed a live
Externí odkaz:
https://doaj.org/article/97b3d56fdc484231b8060bf4b1c73a2a
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
Gamete fusion is the climax of fertilization in all sexually reproductive organisms, from unicellular fungi to humans. Similarly to other cell-cell fusion events, gamete fusion is mediated by specialized proteins, named fusogens, that overcome the en
Externí odkaz:
https://doaj.org/article/f5ebac645b9e43a99c8b67866d3c778f
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 7, p e1009185 (2021)
Complex dendritic trees are a distinctive feature of neurons. Alterations to dendritic morphology are associated with developmental, behavioral and neurodegenerative changes. The highly-arborized PVD neuron of C. elegans serves as a model to study de
Externí odkaz:
https://doaj.org/article/0acfbdeadd3f47eb9e50a23a84e01936
Autor:
Ksenia Smurova, Benjamin Podbilewicz
Publikováno v:
Cell Reports, Vol 14, Iss 6, Pp 1517-1527 (2016)
Cell-cell fusion plays essential roles during fertilization and organogenesis. Previous studies in C. elegans led to the identification of the eukaryotic fusion protein (EFF-1 fusogen), which has structural homology to class II viral fusogens. Transc
Externí odkaz:
https://doaj.org/article/a2a5e54ca3c1401aa733030ab2a4a084
Autor:
Sajedah M. Hindi, Michael J. Petrany, Elena Greenfeld, Leah C. Focke, Alyssa A.W. Cramer, Michael A. Whitt, Vikram Prasad, Jeffrey S. Chamberlain, Benjamin Podbilewicz, Douglas P. Millay
Publikováno v:
bioRxiv
SummaryEntry of enveloped viruses into cells is mediated by fusogenic proteins that form a complex between membranes to drive rearrangements needed for fusion. Skeletal muscle development also requires membrane fusion events between progenitor cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88b91a4a4ddb2a88c9938b3657a89b83
https://europepmc.org/articles/PMC10055243/
https://europepmc.org/articles/PMC10055243/
Autor:
Nicolas G. Brukman, Kohdai P. Nakajima, Clari Valansi, Kateryna Flyak, Xiaohui Li, Tetsuya Higashiyama, Benjamin Podbilewicz
Publikováno v:
Journal of Cell Biology. 222
Mammalian sperm–egg adhesion depends on the trans-interaction between the sperm-specific type I glycoprotein IZUMO1 and its oocyte-specific GPI-anchored receptor JUNO. However, the mechanisms and proteins (fusogens) that mediate the following step
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db6830f9b6e23cce03b67d6d15b12df7
https://doi.org/10.1083/jcb.202207147
https://doi.org/10.1083/jcb.202207147
Autor:
Sudhir Kumar, Clari Valansi, Meseret T. Haile, Xiaohui Li, Kateryna Flyak, Abhisek Dwivedy, Biley A. Abatiyow, Amanda S. Leeb, Spencer Y. Kennedy, Nelly M. Camargo, Ashley M. Vaughan, Nicolas G. Brukman, Benjamin Podbilewicz, Stefan H. I. Kappe
Publikováno v:
Cellular and Molecular Life Sciences. 79
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3a8a52a0083e686cbf5c3a26bafeedb
https://doi.org/10.1007/s00018-022-04583-w
https://doi.org/10.1007/s00018-022-04583-w