Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Benjamin Petsch"'
Autor:
Charlie Fricke, Lorenz Ulrich, Jana Kochmann, Janina Gergen, Kristina Kovacikova, Nicole Roth, Julius Beer, Daniel Schnepf, Thomas C. Mettenleiter, Susanne Rauch, Benjamin Petsch, Donata Hoffmann, Martin Beer, Björn Corleis, Anca Dorhoi
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 4, Pp 102360- (2024)
Coronavirus disease 2019 (COVID-19) mRNA vaccines that have contributed to controlling the SARS-CoV-2 pandemic induce specific serum antibodies, which correlate with protection. However, the neutralizing capacity of antibodies for emerging SARS-CoV-2
Externí odkaz:
https://doaj.org/article/3e2482e7ad3145ddb672914b9dc73a4d
Autor:
PLOS Pathogens Editors, Johannes Haybaeck, Mathias Heikenwalder, Britta Klevenz, Petra Schwarz, Ilan Margalith, Claire Bridel, Kirsten Mertz, Elizabeta Zirdum, Benjamin Petsch, Thomas J Fuchs, Lothar Stitz, Adriano Aguzzi
Publikováno v:
PLoS Pathogens, Vol 20, Iss 7, p e1012396 (2024)
Externí odkaz:
https://doaj.org/article/dca854d308c848918555e1b6afe268ac
Autor:
Puthupparampil V. Scaria, Nicole Roth, Kim Schwendt, Olga V. Muratova, Nada Alani, Lynn E. Lambert, Emma K. Barnafo, Christopher G. Rowe, Irfan U. Zaidi, Kelly M. Rausch, David L. Narum, Benjamin Petsch, Patrick E. Duffy
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-10 (2024)
Abstract Malaria transmission-blocking vaccines (TBV) are designed to inhibit the sexual stage development of the parasite in the mosquito host and can play a significant role in achieving the goal of malaria elimination. Preclinical and clinical stu
Externí odkaz:
https://doaj.org/article/c1b01465fd85446dbc27c45b0c566753
Autor:
Sandro Roier, Vidya Mangala Prasad, Monica M. McNeal, Kelly K. Lee, Benjamin Petsch, Susanne Rauch
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-14 (2023)
Abstract Despite the availability of live-attenuated oral vaccines, rotavirus remains a major cause of severe childhood diarrhea worldwide. Due to the growing demand for parenteral rotavirus vaccines, we developed mRNA-based vaccine candidates target
Externí odkaz:
https://doaj.org/article/70a0ce611d5c48458c7612f1572ea4ff
Autor:
Fredrika Hellgren, Alberto Cagigi, Rodrigo Arcoverde Cerveira, Sebastian Ols, Theresa Kern, Ang Lin, Bengt Eriksson, Michael G. Dodds, Edith Jasny, Kim Schwendt, Conrad Freuling, Thomas Müller, Martin Corcoran, Gunilla B. Karlsson Hedestam, Benjamin Petsch, Karin Loré
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Licensed rabies virus vaccines based on whole inactivated virus are effective in humans. However, there is a lack of detailed investigations of the elicited immune response, and whether responses can be improved using novel vaccine platforms
Externí odkaz:
https://doaj.org/article/9771c5f02b3e441f9d36ad976beb085c
Autor:
Lex G. Medina-Magües, Janine Mühe, Edith Jasny, Emily S. Medina-Magües, Nicole Roth, Jaime Lopera-Madrid, Cristhian Salas-Quinchucua, Cole Knuese, Benjamin Petsch, Jorge E. Osorio
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-13 (2023)
Abstract Despite the success of the widely used attenuated yellow fever (YF) vaccine, its global supply remains a substantial barrier to implementing vaccination campaigns in endemic regions and combating emerging epidemics. In A129 mice and rhesus m
Externí odkaz:
https://doaj.org/article/e9dc3833af49423a81facd752df629d8
Autor:
Casey Hensley, Sandro Roier, Peng Zhou, Sofia Schnur, Charlotte Nyblade, Viviana Parreno, Annie Frazier, Maggie Frazier, Kelsey Kiley, Samantha O’Brien, Yu Liang, Bryan T. Mayer, Ruizhe Wu, Celia Mahoney, Monica M. McNeal, Benjamin Petsch, Susanne Rauch, Lijuan Yuan
Publikováno v:
Vaccines, Vol 12, Iss 3, p 260 (2024)
Human rotavirus (HRV) is still a leading cause of severe dehydrating gastroenteritis globally, particularly in infants and children. Previously, we demonstrated the immunogenicity of mRNA-based HRV vaccine candidates expressing the viral spike protei
Externí odkaz:
https://doaj.org/article/cb5a7873ad0641e491f027758ab5b5e0
Autor:
Björn Corleis, Donata Hoffmann, Susanne Rauch, Charlie Fricke, Nicole Roth, Janina Gergen, Kristina Kovacikova, Kore Schlottau, Nico Joel Halwe, Lorenz Ulrich, Jacob Schön, Kerstin Wernike, Marek Widera, Sandra Ciesek, Stefan O. Mueller, Thomas C. Mettenleiter, Domenico Maione, Benjamin Petsch, Martin Beer, Anca Dorhoi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-8 (2023)
Here the authors show efficacy of a low-dose, unmodified, bivalent mRNA vaccine against SARS-CoV-2 variants in two female rodent models and find that combination of mRNA encoding Beta and Delta Spike sequences induces broadly neutralizing antibodies
Externí odkaz:
https://doaj.org/article/77d9be65187e4f7688c69da5795d81d2
Autor:
Klara Lenart, Fredrika Hellgren, Sebastian Ols, Xianglei Yan, Alberto Cagigi, Rodrigo Arcoverde Cerveira, Inga Winge, Jakub Hanczak, Stefan O. Mueller, Edith Jasny, Kim Schwendt, Susanne Rauch, Benjamin Petsch, Karin Loré
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 27, Iss , Pp 309-323 (2022)
A third vaccine dose is often required to achieve potent, long-lasting immune responses. We investigated the effect of three 8-μg doses of CVnCoV, CureVac’s severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine candidate containing
Externí odkaz:
https://doaj.org/article/7fe635994c564778a82c953e5d6c3cf7
Autor:
Makda S. Gebre, Susanne Rauch, Nicole Roth, Janina Gergen, Jingyou Yu, Xiaowen Liu, Andrew C. Cole, Stefan O. Mueller, Benjamin Petsch, Dan H. Barouch
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-7 (2022)
Abstract mRNA vaccines can be developed and produced quickly, making them prime candidates for immediate outbreak responses. Furthermore, clinical trials have demonstrated rapid protection following mRNA vaccination. Thus, we sought to investigate ho
Externí odkaz:
https://doaj.org/article/a805989bd87b42629b9dba91cb15c05e