Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Benjamin P.C. Chen"'
Autor:
Yue Lang, Dexuan Gao, Lan Yu, Xiang-Xiang Zhang, Debabrata Saha, Benjamin P.C. Chen, Meng-Meng Gu, Zeng-Fu Shang
Publikováno v:
Genes and Diseases, Vol 11, Iss 6, Pp 101139- (2024)
Externí odkaz:
https://doaj.org/article/9a6a25c58c6d408699311fe4d514d614
Autor:
Xiangyi Li, GuemHee Baek, Suzanne Carreira, Wei Yuan, Shihong Ma, Mia Hofstad, Sora Lee, Yunpeng Gao, Claudia Bertan, Maria de los Dolores Fenor de la Maza, Prasanna G. Alluri, Sandeep Burma, Benjamin P.C. Chen, Ganesh V. Raj, Johann de Bono, Yves Pommier, Ram S. Mani
Publikováno v:
JCI Insight, Vol 7, Iss 9 (2022)
The bromodomain and extraterminal (BET) family of chromatin reader proteins bind to acetylated histones and regulate gene expression. The development of BET inhibitors (BETi) has expanded our knowledge of BET protein function beyond transcriptional r
Externí odkaz:
https://doaj.org/article/313bc418126f4d83b8d5e5bb70fcba71
Publikováno v:
Cellular Physiology and Biochemistry, Vol 50, Iss 2, Pp 597-611 (2018)
Background/Aims: Hyperglycemia has been shown to increase the incidence and metastasis in various types of cancers. However, the correlation between hyperglycemia and lymphatic metastasis in prostate cancer (PCa) remains unclear. Our previous study d
Externí odkaz:
https://doaj.org/article/2ebf764b292a4985a73a4bdfc8c35e89
Autor:
Kyung-Jong Lee, Zeng-Fu Shang, Yu-Fen Lin, Jingxin Sun, Keiko Morotomi-Yano, Debabrata Saha, Benjamin P.C. Chen
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 17, Iss 4, Pp 329-338 (2015)
DNA-dependent protein kinase catalytic subunit (DNA-PKcs) is the key regulator of the non-homologous end joining pathway of DNA double-strand break repair. We have previously reported that DNA-PKcs is required for maintaining chromosomal stability an
Externí odkaz:
https://doaj.org/article/8fd8c5893a99441a974fcf0b9bab6b9a
Autor:
Yong-Zhong Wu, Ying Wang, Jing Zhang, Qing-Ming Jiang, Hong-Lei Tu, Hao-Nan Yang, Nuo-Han Wang, Meng-Qi Yang, Ping Huang, Benjamin P.C. Chen, Zheng Tang, Jiang-Dong Sui
Supplementary Figure from Protein Phosphatase 2A–Dependent Mitotic hnRNPA1 Dephosphorylation and TERRA Formation Facilitate Telomere Capping
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b357e3e70d3b55dbc12e781b8217129f
https://doi.org/10.1158/1541-7786.22527929.v1
https://doi.org/10.1158/1541-7786.22527929.v1
Autor:
Ganesh V. Raj, Benjamin P.C. Chen, Ram S. Mani, Scott M. Dehm, Johann S. de Bono, Sandeep Burma, Felix Y. Feng, Neil B. Desai, Chao Xing, Solomon L. Woldu, Xihui Liu, Ryan Hutchinson, Xiangyi Li, Mohammed S. Kanchwala, Yunpeng Gao, Zhao Liu, Sam Ding, Susmita G. Ramanand, GuemHee Baek, Jeffrey Li, Sentai Ding, Kangling Xu, Rui Li, Yi Yin
ARV mediates DDR and clonogenic survival.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab34a344390b5ee39c68d750fa7a888c
https://doi.org/10.1158/0008-5472.22414325.v1
https://doi.org/10.1158/0008-5472.22414325.v1
Autor:
Ganesh V. Raj, Benjamin P.C. Chen, Ram S. Mani, Scott M. Dehm, Johann S. de Bono, Sandeep Burma, Felix Y. Feng, Neil B. Desai, Chao Xing, Solomon L. Woldu, Xihui Liu, Ryan Hutchinson, Xiangyi Li, Mohammed S. Kanchwala, Yunpeng Gao, Zhao Liu, Sam Ding, Susmita G. Ramanand, GuemHee Baek, Jeffrey Li, Sentai Ding, Kangling Xu, Rui Li, Yi Yin
In prostate cancer, androgen deprivation therapy (ADT) enhances the cytotoxic effects of radiotherapy. This effect is associated with weakening of the DNA damage response (DDR) normally supported by the androgen receptor. As a significant number of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e8f14bd1858f8a19b54cb8d7eec7525
https://doi.org/10.1158/0008-5472.c.6508943.v1
https://doi.org/10.1158/0008-5472.c.6508943.v1
Autor:
Jer-Tsong Hsieh, Benjamin P.C. Chen, Seung Tae Baek, Debabrata Saha, Ho Lin, Chih-Ho Lai, Dalin He, Kaijie Wu, James Brugarolas, Payal Kapur, Nathan Kim, Joyce Allison, Wei-Min Chen, Jiaming Guo, Elizabeth Hernandez, Andrew Dang, Chun-Jung Lin, Eun-Jin Yun
Purpose:Renal cell carcinoma (RCC) is known to be highly radioresistant but the mechanisms associated with radioresistance have remained elusive. We found DOC-2/DAB2 interactive protein (DAB2IP) frequently downregulated in RCC, is associated with rad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::776d3181f799b477e6e99b2e5de0fbc6
https://doi.org/10.1158/1078-0432.c.6528284
https://doi.org/10.1158/1078-0432.c.6528284
Autor:
Jer-Tsong Hsieh, Benjamin P.C. Chen, Seung Tae Baek, Debabrata Saha, Ho Lin, Chih-Ho Lai, Dalin He, Kaijie Wu, James Brugarolas, Payal Kapur, Nathan Kim, Joyce Allison, Wei-Min Chen, Jiaming Guo, Elizabeth Hernandez, Andrew Dang, Chun-Jung Lin, Eun-Jin Yun
Figure S1. DAB2IP expression does not affect key repair factors in NHEJ (Ku70, Ku80) and HR (RAD51, BRCA1) and PARP-1 mRNA expression. Figure S2. RANBP2, TRIP12, and RNF40 interact with both DAB2IP and PARP-1. Figure S3. Radiotherapy of RCC xenograft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60d83f8e953b6c1faa8e8370ca9382a7
https://doi.org/10.1158/1078-0432.22472636.v1
https://doi.org/10.1158/1078-0432.22472636.v1
Autor:
David K. Ann, David J. Chen, Benjamin P.C. Chen, Yun Yen, Clay C.C. Wang, H. Helen Lin, Shih-Ya Wang, Lee Ming Boo, Angela Y.J. Li
Supplementary Figure 1 from Suppression of Nonhomologous End Joining Repair by Overexpression of HMGA2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0019f2470fe7fa116a2bfbf1f6cc6a44
https://doi.org/10.1158/0008-5472.22378407.v1
https://doi.org/10.1158/0008-5472.22378407.v1