Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Benjamin P. Steil"'
Autor:
Wilfried A.M. Bakker, Benjamin P. Steil, Robert E. Johnston, Mario Barro, Patricia A. Jorquera, Janny Westdijk
Publikováno v:
Vaccine. 32:558-563
The eradication of poliovirus from the majority of the world has been achieved through the use of two vaccines: the inactivated poliovirus vaccine (IPV) and the live-attenuated oral poliovirus vaccine (OPV). Both vaccines are effective at preventing
Autor:
Mario Barro, Thomas S. Vedvick, Benjamin P. Steil, Gideon F.A. Kersten, Nicolas Collin, Janny Westdijk, Patrick Koedam, Wilfried A.M. Bakker, Peter van der Ley
Publikováno v:
Vaccine, 31(9), 1298-1304
Vaccine, vol. 31, no. 9, pp. 1298-1304
Vaccine, vol. 31, no. 9, pp. 1298-1304
Six different adjuvants, each in combination with inactivated polio vaccine (IPV) produced with attenuated Sabin strains (sIPV), were evaluated for their ability to enhance virus neutralizing antibody titers (VNTs) in the rat potency model. The incre
Publikováno v:
Journal of Virology. 84:2843-2858
A 3′ poly(A) tail is a common feature of picornavirus RNA genomes and the RNA genomes of many other positive-strand RNA viruses. We examined the manner in which the homopolymeric poly(A) and poly(U) portions of poliovirus (PV) positive- and negativ
Autor:
Benjamin P. Steil, David J. Barton
Publikováno v:
Journal of Virology. 82:9400-9408
Initiation of RNA synthesis by RNA-dependent RNA polymerases occurs when a phosphodiester bond is formed between the first two nucleotides in the 5′ terminus of product RNA. The concentration of initiating nucleoside triphosphates (NTPi) required f
Publikováno v:
Journal of Virology. 78:1393-1402
cis -acting RNA sequences and structures in the 5′ and 3′ nontranslated regions of poliovirus RNA interact with host translation machinery and viral replication proteins to coordinately regulate the sequential translation and replication of polio
Publikováno v:
Journal of virology. 84(16)
The structures of polio-, coxsackie-, and rhinovirus polymerases have revealed a conserved yet unusual protein conformation surrounding their buried N termini where a β-strand distortion results in a solvent-exposed hydrophobic amino acid at residue
Autor:
David J. Barton, Benjamin P. Steil
Publikováno v:
Journal of virology. 83(24)
There are two protein primers involved in picornavirus RNA replication, VPg, the viral protein of the genome, and VPgpUpU OH . A cis -acting replication element (CRE) within the open reading frame of poliovirus (PV) RNA allows the viral RNA-dependent