Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Benjamin Neunstoecklin"'
Autor:
Massimo Morbidelli, Eric Lucas, Thomas K. Villiger, Matthieu Stettler, Benjamin Neunstoecklin, Daniel J. Karst, Hervé Broly, Miroslav Soos
Publikováno v:
Biochemical Engineering Journal. 131:84-94
Transfer of mammalian cell culture processes across stirred and aerated bioreactor scales is a delicate task, frequently leading to different conditions across scales. To provide a more rational reasoning behind scale-up of mammalian cell cultures, p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25405db43f2fb5e93db5653e2f097df0
https://doi.org/10.1016/j.bej.2017.12.004
https://doi.org/10.1016/j.bej.2017.12.004
Autor:
Thomas Solacroup, Benjamin Neunstoecklin, Miroslav Soos, Hervé Broly, Massimo Morbidelli, Matthieu Stettler
Publikováno v:
J. Biotechnol.
Application of quality by design (QbD) requires identification of the maximum operating range for parameters affecting the cell culture process. These include hydrodynamic stress, mass transfer or gradients in dissolved oxygen and pH. Since most of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5370e5a60f5d868b8302732c8ade861
Autor:
Miroslav Soos, Eric Lucas, Massimo Morbidelli, Hervé Broly, Thomas K. Villiger, Benjamin Neunstoecklin, Matthieu Stettler
Although several scaling bioreactor models of mammalian cell cultures are suggested and described in the literature, they mostly lack a significant validation at pilot or manufacturing scale. The aim of this study is to validate an oscillating hydrod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e953b3c60168613632dcc539a8dfe350
http://hdl.handle.net/11311/1015609
http://hdl.handle.net/11311/1015609
Autor:
Hervé Broly, Benjamin Neunstoecklin, Riccardo Leardi, Massimo Morbidelli, Miroslav Soos, Alessandro Butté, Michael Sokolov, Thomas Solacroup, Matthieu Stettler
This work presents a sequential data analysis path, which was successfully applied to identify important patterns (fingerprints) in mammalian cell culture process data regarding process variables, time evolution and process response. The data set inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d248586d35ff9fc62a99ade832d1022
https://hdl.handle.net/11567/865440
https://hdl.handle.net/11567/865440
Autor:
Miroslav Soos, Massimo Morbidelli, Pascal Valax, Ralf Gleixner, Hervé Broly, Alex Eon-Duval, Benjamin Neunstoecklin
Publikováno v:
Therapeutic Fc-Fusion Proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfb20e7825f53af4a8d8cbc124244e23
https://doi.org/10.1002/9783527675272.ch06
https://doi.org/10.1002/9783527675272.ch06
Publikováno v:
New Biotechnology. 29:S12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cb0a62f6b12f0f6aaff0929ca5ee9ba
https://doi.org/10.1016/j.nbt.2012.08.024
https://doi.org/10.1016/j.nbt.2012.08.024
Facing heterogeneities in bioprocesses, a downscale approach tailored to suit large scale conditions
Publikováno v:
New Biotechnology. 29:S74
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::069346307b54f1db1ecf1fcb25cf6874
https://doi.org/10.1016/j.nbt.2012.08.207
https://doi.org/10.1016/j.nbt.2012.08.207