Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Benjamin M. Woolston"'
Autor:
Zachary J. Rogers, Thibault Colombani, Saad Khan, Khushbu Bhatt, Alexandra Nukovic, Guanyu Zhou, Benjamin M. Woolston, Cormac T. Taylor, Daniele M. Gilkes, Nikolai Slavov, Sidi A. Bencherif
Publikováno v:
Advanced Science, Vol 11, Iss 30, Pp n/a-n/a (2024)
Abstract In oxygen (O2)‐controlled cell culture, an indispensable tool in biological research, it is presumed that the incubator setpoint equals the O2 tension experienced by cells (i.e., pericellular O2). However, it is discovered that physioxic (
Externí odkaz:
https://doaj.org/article/1068060eb74c48a59b7780c76e69d254
Autor:
Justin A. Hayes, Anna W. Lunger, Aayushi S. Sharma, Matthew T. Fernez, Rebecca L. Carrier, Abigail N. Koppes, Ryan Koppes, Benjamin M. Woolston
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113481- (2023)
Summary: Hydrogen sulfide (H2S) is a gaseous microbial metabolite whose role in gut diseases is debated, with contradictory results stemming from experimental difficulties associated with accurate dosing and measuring H2S and the use of model systems
Externí odkaz:
https://doaj.org/article/d57976c512774e30b997348188a3aa5b
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Engineering E. coli for metabolization of methanol to produce fuels and chemicals has not been fully achieved. Here, the authors combine metabolic engineering and chemical inhibition to improve methanol assimilation and distinguish the role of kineti
Externí odkaz:
https://doaj.org/article/60acd311edfb421fb3ff1741090fb9a0
Autor:
Justin A. Hayes, Anna W. Lunger, Aayushi S. Sharma, Matthew T. Fernez, Abigail N. Koppes, Ryan Koppes, Benjamin M. Woolston
Publikováno v:
bioRxiv
Hydrogen sulfide (H2S) is a gaseous microbial metabolite whose role in gut diseases is debated, largely due to the difficulty in controlling its concentration and the use of non-representative model systems in previous work. Here, we engineeredE. col
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d39249ab383718b84453ecd5283edd0
https://doi.org/10.1101/2023.05.16.538950
https://doi.org/10.1101/2023.05.16.538950
Publikováno v:
FEMS Microbiology Letters. 370
Eubacterium limosum is an acetogenic bacterium of potential industrial relevance for its ability to efficiently metabolize a range of single carbon compounds. However, extracellular polymeric substance (EPS) produced by the type strain ATCC 8486 is a
Autor:
Benjamin M. Woolston
Publikováno v:
Trends in Biotechnology. 40:1399-1400
Replacing petroleum-based fuels in high-power sectors like aviation and rocketry is a major sustainability challenge. Polycyclopropanated hydrocarbons provide excellent fuel characteristics for these applications, but their synthesis is challenging.
Autor:
Patrick A Sanford, Benjamin M Woolston
Publikováno v:
Journal of industrial microbiologybiotechnology. 49(5)
Acetogenic bacteria are an increasingly popular choice for producing fuels and chemicals from single carbon (C1) substrates. Eubacterium limosum is a promising acetogen with several native advantages, including the ability to catabolize a wide repert
Autor:
Seth M. Bloom, Nomfuneko A. Mafunda, Benjamin M. Woolston, Matthew R. Hayward, Josephine F. Frempong, Aaron B. Abai, Jiawu Xu, Alissa J. Mitchell, Xavier Westergaard, Fatima A. Hussain, Nondumiso Xulu, Mary Dong, Krista L. Dong, Thandeka Gumbi, F. Xolisile Ceasar, Justin K. Rice, Namit Choksi, Nasreen Ismail, Thumbi Ndung’u, Musie S. Ghebremichael, David A. Relman, Emily P. Balskus, Caroline M. Mitchell, Douglas S. Kwon
Publikováno v:
Nature Microbiology
Vaginal microbiota composition affects many facets of reproductive health. Lactobacillus iners-dominated microbial communities are associated with poorer outcomes, including higher risk of bacterial vaginosis (BV), compared with vaginal microbiota ri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e589b387f722b1e9cde10f87f6b221ae
https://hdl.handle.net/21.11116/0000-000A-2C90-221.11116/0000-000A-2C92-0
https://hdl.handle.net/21.11116/0000-000A-2C90-221.11116/0000-000A-2C92-0
Autor:
Benjamin M. Woolston
Publikováno v:
Trends in Biotechnology. 37:1273-1276
Single carbon (C1) feedstocks are attractive for bioconversion, but native C1 assimilation pathways are difficult to engineer. Chou et al. developed a novel process for elongating the C1 compound formyl-CoA. Besides demonstrating a new approach for C
Autor:
Kathryn O Hoyt, Benjamin M Woolston
Publikováno v:
Current opinion in biotechnology. 75
Single-carbon (C1, or one-carbon) substrates are promising feedstocks for sustainable biofuel and biochemical production. Crucial to the goal of engineering C1-utilizing strains for improved production is a quantitative understanding of the organizat