Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Benjamin M. Janus"'
Autor:
Matthew C. Metcalf, Benjamin M. Janus, Rui Yin, Ruixue Wang, Johnathan D. Guest, Edwin Pozharski, Mansun Law, Roy A. Mariuzza, Eric A. Toth, Brian G. Pierce, Thomas R. Fuerst, Gilad Ofek
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Hepatitis C virus (HCV) is a major global health burden as the leading causative agent of chronic liver disease and hepatocellular carcinoma. While the main antigenic target for HCV-neutralizing antibodies is the membrane-associated E1E2 sur
Externí odkaz:
https://doaj.org/article/5c8f3813e8b4474bb3fa9ada06482823
Autor:
Andrey Romanyuk, Ruixue Wang, Alexander Marin, Benjamin M. Janus, Eric I. Felner, Dengning Xia, Yenny Goez-Gazi, Kendra J. Alfson, Abdul S. Yunus, Eric A. Toth, Gilad Ofek, Ricardo Carrion, Mark R. Prausnitz, Thomas R. Fuerst, Alexander K. Andrianov
Publikováno v:
Journal of Functional Biomaterials, Vol 14, Iss 1, p 16 (2022)
Ebolavirus (EBOV) infection in humans is a severe and often fatal disease, which demands effective interventional strategies for its prevention and treatment. The available vaccines, which are authorized under exceptional circumstances, use viral vec
Externí odkaz:
https://doaj.org/article/a885540978ff4542aea23a7fac2aa739
Autor:
Benjamin M. Janus, Nydia van Dyk, Xuelian Zhao, Katie A. Howell, Cinque Soto, M. Javad Aman, Yuxing Li, Thomas R. Fuerst, Gilad Ofek
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
The Ebola virus glycoprotein is a target for cross-protective antibodies. Here, Janus et al. report the crystal structure of the antigen-binding fragment of a pan-reactive antibody bound to a conserved epitope of the glycoprotein, facilitating ration
Externí odkaz:
https://doaj.org/article/20e66fb349b04412a89f063ca2921f9c
Autor:
Neelakshi Gohain, Susie Min, S Rerks-Ngarm, Benjamin M. Janus, Georgia D. Tomaras, Barton F. Haynes, Jerome H. Kim, Matthew Zirui Tay, Nelson L. Michael, Merlin L. Robb, Peng Zhang, Jaranit Kaewkungwal, Guido Ferrari, David C. Montefiori, Mangala Rao, David Easterhoff, Matina Kakalis, Jean-Louis Excler, Faruk Sinangil, Anthony Monroe, Kwan-Ki Hwang, Mattia Bonsignori, M. Gordon Joyce, James Arthos, Kevin Wiehe, Eden P. Go, Gilad Ofek, Kristina K. Peachman, Paolo Lusso, Sanjay Phogat, S Nitayaphan, LaTonya D. Williams, Sandhya Vasan, James Tartaglia, M. Anthony Moody, Misook Choe, Punnee Pitisuttithum, Kan Luo, Charles Beck, Robert J. O'Connell, Heather Desaire, Kevin O. Saunders, Justin Pollara
Publikováno v:
JCI Insight. 5
In the RV144 HIV-1 phase III trial, vaccine efficacy directly correlated with the magnitude of the variable region 2–specific (V2-specific) IgG antibody response, and in the presence of low plasma IgA levels, with the magnitude of plasma antibody-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af748846c34939e86bd6af7486c2c731
https://doi.org/10.1172/jci.insight.131437
https://doi.org/10.1172/jci.insight.131437
Autor:
Xuelian Zhao, Yuxing Li, Nydia van Dyk, Gilad Ofek, M. Javad Aman, Katie A. Howell, Thomas R. Fuerst, Benjamin M. Janus, Cinque Soto
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Nature Communications
Nature Communications
The severity of the 2014–2016 ebolavirus outbreak in West Africa expedited clinical development of therapeutics and vaccines though the countermeasures on hand were largely monospecific and lacked efficacy against other ebolavirus species that prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68dde91a68f96e033e59eb1d492566a0
https://doaj.org/article/20e66fb349b04412a89f063ca2921f9c
https://doaj.org/article/20e66fb349b04412a89f063ca2921f9c