Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Benjamin M. Hiller"'
Autor:
Benjamin M. Hiller, David J. Marmion, Cayla A. Thompson, Nathaniel A. Elliott, Howard Federoff, Patrik Brundin, Virginia B. Mattis, Christopher W. McMahon, Jeffrey H. Kordower
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-15 (2022)
Abstract In pursuit of treating Parkinson’s disease with cell replacement therapy, differentiated induced pluripotent stem cells (iPSC) are an ideal source of midbrain dopaminergic (mDA) cells. We previously established a protocol for differentiati
Externí odkaz:
https://doaj.org/article/935613851567435890b73366f2592369
Autor:
Benjamin M. Hiller, David J. Marmion, Rachel M. Gross, Cayla A. Thompson, Carrie A. Chavez, Patrik Brundin, Dustin R. Wakeman, Christopher W. McMahon, Jeffrey H. Kordower
Publikováno v:
Stem Cells Translational Medicine, Vol 10, Iss 2, Pp 278-290 (2021)
Abstract Nongenetic methodologies to reduce undesirable proliferation would be valuable when generating dopamine neurons from stem cells for transplantation in Parkinson's disease (PD). To this end, we modified an established method for controlled di
Externí odkaz:
https://doaj.org/article/f01fe3c0dbb64c11a6b43d6f7c6c3c41
Autor:
David J. Marmion, Angela A. Rutkowski, Diptaman Chatterjee, Benjamin M. Hiller, Milton H. Werner, Erwan Bezard, Deniz Kirik, Thomas McCown, Steven J. Gray, Jeffrey H. Kordower
Publikováno v:
Neurobiology of Disease, Vol 148, Iss , Pp 105184- (2021)
Multiple system atrophy (MSA) is a rare and extremely debilitating progressive neurodegenerative disease characterized by variable combinations of parkinsonism, cerebellar ataxia, dysautonomia, and pyramidal dysfunction. MSA is a unique synucleinopat
Externí odkaz:
https://doaj.org/article/a5bad6c2bad44d15846ecd9b79a9ef39
Autor:
Dustin R. Wakeman, Benjamin M. Hiller, David J. Marmion, Christopher W. McMahon, Grant T. Corbett, Kile P. Mangan, Junyi Ma, Lauren E. Little, Zhong Xie, Tamara Perez-Rosello, Jaime N. Guzman, D. James Surmeier, Jeffrey H. Kordower
Publikováno v:
Stem Cell Reports, Vol 9, Iss 1, Pp 149-161 (2017)
A major challenge for clinical application of pluripotent stem cell therapy for Parkinson's disease (PD) is large-scale manufacturing and cryopreservation of neurons that can be efficiently prepared with minimal manipulation. To address this obstacle
Externí odkaz:
https://doaj.org/article/0af637ef3a9f474e93fae6c09d34903c
Autor:
Rachel M. Gross, David J. Marmion, Patrik Brundin, Christopher W. McMahon, Cayla A. Thompson, Jeffrey H. Kordower, Benjamin M. Hiller, Carrie Chavez, Dustin R. Wakeman
Publikováno v:
Stem Cells Translational Medicine
Stem Cells Translational Medicine, Vol 10, Iss 2, Pp 278-290 (2021)
Stem Cells Translational Medicine, Vol 10, Iss 2, Pp 278-290 (2021)
Nongenetic methodologies to reduce undesirable proliferation would be valuable when generating dopamine neurons from stem cells for transplantation in Parkinson's disease (PD). To this end, we modified an established method for controlled differentia
Autor:
Benjamin M. Hiller, David J. Marmion, Cayla A. Thompson, Nathaniel A. Elliott, Howard Federoff, Patrik Brundin, Virginia B. Mattis, Christopher W. McMahon, Jeffrey H. Kordower
Publikováno v:
NPJ Regenerative medicine. 7(1)
In pursuit of treating Parkinson’s disease with cell replacement therapy, differentiated induced pluripotent stem cells (iPSC) are an ideal source of midbrain dopaminergic (mDA) cells. We previously established a protocol for differentiating iPSC-d
Autor:
Milton H. Werner, Jeffrey H. Kordower, Deniz Kirik, Erwan Bezard, Angela A. Rutkowski, Benjamin M. Hiller, David J. Marmion, Steven J. Gray, Thomas J. McCown, Diptaman Chatterjee
Publikováno v:
Neurobiology of Disease, Vol 148, Iss, Pp 105184-(2021)
Multiple system atrophy (MSA) is a rare and extremely debilitating progressive neurodegenerative disease characterized by variable combinations of parkinsonism, cerebellar ataxia, dysautonomia, and pyramidal dysfunction. MSA is a unique synucleinopat
Autor:
Kile P. Mangan, Dustin R. Wakeman, David J. Marmion, Zhong Xie, Benjamin M. Hiller, Jeffrey H. Kordower, Tamara Perez-Rosello, Lauren E. Little, Jaime N. Guzman, Junyi Ma, D. James Surmeier, Grant T. Corbett, Christopher W. McMahon
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 9, Iss 1, Pp 149-161 (2017)
Stem Cell Reports, Vol 9, Iss 1, Pp 149-161 (2017)
Summary A major challenge for clinical application of pluripotent stem cell therapy for Parkinson's disease (PD) is large-scale manufacturing and cryopreservation of neurons that can be efficiently prepared with minimal manipulation. To address this