Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Benjamin M. Akiyama"'
Autor:
Monica E. Graham, Camille Merrick, Benjamin M. Akiyama, Matthew J. Szucs, Sarah Leach, Jeffery S. Kieft, J. David Beckham
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT All flaviviruses contain conserved RNA structures in the 3′ untranslated region (3′ UTR) that are important for flavivirus RNA replication, translation, and pathogenesis. Flaviviruses like Zika virus (ZIKV) contain multiple conserved RNA
Externí odkaz:
https://doaj.org/article/d5522a994a9d430da44cb34e19c0a423
Publikováno v:
Nucleic Acids Research
Mosquito-borne flaviviruses (MBFVs) including dengue, West Nile, yellow fever, and Zika viruses have an RNA genome encoding one open reading frame flanked by 5′ and 3′ untranslated regions (UTRs). The 3′ UTRs of MBFVs contain regions of high se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1aa0c8fecc2e9b95bf858021e8081fd
http://europepmc.org/articles/PMC8266583
http://europepmc.org/articles/PMC8266583
Publikováno v:
Viruses
Volume 12
Issue 10
Viruses, Vol 12, Iss 1177, p 1177 (2020)
Volume 12
Issue 10
Viruses, Vol 12, Iss 1177, p 1177 (2020)
The Zika virus (ZIKV), like other flaviviruses, produces several species of sub-genomic RNAs (sfRNAs) during infection, corresponding to noncoding RNA fragments of different lengths that result from the exonuclease degradation of the viral 3&prime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12a2e745642aaf3138a7bf0607f54070
Zika virus (ZIKV), like other flaviviruses, produces several species of sub-genomic RNAs (sfRNAs) during infection, corresponding to noncoding RNA fragments of different lengths derived from the viral 3’ untranslated region (UTR). Over the course o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63535d9b377e862cf92f06472f97ce8a
https://doi.org/10.1101/2020.09.10.281949
https://doi.org/10.1101/2020.09.10.281949
Different tertiary interactions create the same important 3D features in a distinct flavivirus xrRNA
Autor:
Quentin Vicens, Rachel A. Jones, Anna-Lena Steckelberg, Jeffrey S. Kieft, Benjamin M. Akiyama, Matthew J. Szucs
Publikováno v:
RNA
During infection by a flavivirus (FV), cells accumulate noncoding subgenomic flavivirus RNAs (sfRNAs) that interfere with several antiviral pathways. These sfRNAs are formed by structured RNA elements in the 3′ untranslated region (UTR) of the vira
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db4be5423068532630e8ca2f4358e3b6
https://pubmed.ncbi.nlm.nih.gov/33004436
https://pubmed.ncbi.nlm.nih.gov/33004436
Autor:
Quentin Vicens, Anna-Lena Steckelberg, Rachel A. Jones, Jeffrey S. Kieft, Benjamin M. Akiyama, Matthew J. Szucs
During infection by a flavivirus (FV), cells accumulate noncoding subgenomic flavivirus RNAs (sfRNAs) that interfere with several antiviral pathways. These sfRNAs are formed by structured RNA elements in the 3′ untranslated region (UTR) of the vira
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::037402a58fa54f4511348d8f25033669
https://doi.org/10.1101/2020.06.25.172429
https://doi.org/10.1101/2020.06.25.172429
Autor:
Anna-Lena Steckelberg, Benjamin M. Akiyama, Jeffrey S. Kieft, David A. Costantino, Jay C. Nix, Tim L. Sit
Publikováno v:
Proceedings of the National Academy of Sciences. 115:6404-6409
Folded RNA elements that block processive 5' → 3' cellular exoribonucleases (xrRNAs) to produce biologically active viral noncoding RNAs have been discovered in flaviviruses, potentially revealing a new mode of RNA maturation. However, whether this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d77de2c083fd25184f1ff446afd432d
https://doi.org/10.1073/pnas.1802429115
https://doi.org/10.1073/pnas.1802429115
Publikováno v:
Current Opinion in Structural Biology. 36:40-47
Cells contain powerful RNA decay machinery to eliminate unneeded RNA from the cell, and this process is an important and regulated part of controlling gene expression. However, certain structured RNAs have been found that can robustly resist degradat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::514b83d34fd2a88f7f05884cc84b537a
https://doi.org/10.1016/j.sbi.2015.12.006
https://doi.org/10.1016/j.sbi.2015.12.006
Autor:
David A. Costantino, Benjamin M. Akiyama, Jay C. Nix, Jeffrey S. Kieft, Anna-Lena Steckelberg, Tim L. Sit
Folded RNA elements that block processive 5′→3′ cellular exoribonucleases (xrRNAs) to produce biologically active viral non-coding RNAs were discovered in flaviviruses, potentially revealing a new mode of RNA maturation. However, it was unknown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4206f197706ffe815391a3500dea9ee3
Publikováno v:
Journal of Biological Chemistry. 288:22141-22149
The ends of linear chromosomes are extended by telomerase, a ribonucleoprotein complex minimally consisting of a protein subunit called telomerase reverse transcriptase (TERT) and the telomerase RNA (TER). TERT functions by reverse transcribing a sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1941977bbf9e23fd96fe35fca6154be3
https://doi.org/10.1074/jbc.m113.452425
https://doi.org/10.1074/jbc.m113.452425