Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Benjamin M Shykind"'
Autor:
Elizaveta V Bashkirova, Nell Klimpert, Kevin Monahan, Christine E Campbell, Jason Osinski, Longzhi Tan, Ira Schieren, Ariel Pourmorady, Beka Stecky, Gilad Barnea, Xiaoliang Sunney Xie, Ishmail Abdus-Saboor, Benjamin M Shykind, Bianca J Marlin, Richard M Gronostajski, Alexander Fleischmann, Stavros Lomvardas
Publikováno v:
eLife, Vol 12 (2023)
Olfactory receptor (OR) choice represents an example of genetically hardwired stochasticity, where every olfactory neuron expresses one out of ~2000 OR alleles in the mouse genome in a probabilistic, yet stereotypic fashion. Here, we propose that top
Externí odkaz:
https://doaj.org/article/e923cd877d264e7291581c56826388d1
Publikováno v:
Genes & Development. 11:397-407
The mechanism of coactivation by DNA topoisomerase I (topo I) was examined in a highly defined in vitro transcription system containing Pol II and purified factors. Both stimulation of the basal reaction and coactivation occurred dependent on TAF(II)
Publikováno v:
Journal of Biological Chemistry. 271:18405-18412
An activity that modulated the relative levels of transcription from the adenovirus major late promoter (MLP), and the immunoglobulin heavy chain μ promoter (μ) was purified as a 90-kDa factor. This factor is suggested to be a heterotetramer of two
Publikováno v:
Journal of Biological Chemistry. 269:18414-18421
The minimal requirements for transcription initiation from supercoiled templates were determined for the two major forms of TATA-binding factors found in cell extracts, the 300-kDa B-TFIID and the 1000-kDa D-TFIID complexes. As had been observed for
Autor:
Richard Axel, Monica Mendelsohn, Gilad Barnea, Adriana Nemes, Benjamin M. Shykind, S.Christy Rohani, Sean O'Donnell, Yonghua Sun
Publikováno v:
Cell. 117(6)
Individual olfactory sensory neurons express only a single odorant receptor from a large family of genes, and this singularity is an essential feature in models of olfactory perception. We have devised a genetic strategy to examine the stability of r
Publikováno v:
Genesdevelopment. 9(11)
The nonhistone chromosomal protein HMG-2 was identified as a factor necessary for activation in a defined transcription reaction in vitro containing RNA polymerase II and purified factors. Activation occurred on all promoters assayed except that of t
Autor:
Benjamin M. Shykind
Publikováno v:
Human Molecular Genetics. 14:1903-1903
Autor:
Eleanor M. Williams, Benjamin M. Shykind, Megan Walker, Barbara J. Trask, Joseph A. Ross, Robert P. Lane, Lori Tonnes-Priddy, Janet M. Young
Publikováno v:
Genome Biology. 4:R71
The olfactory receptor gene family is one of the largest in the mammalian genome. Previous computational analyses have identified approximately 1,500 mouse olfactory receptors, but experimental evidence confirming olfactory function is available for