Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Benjamin M Dale"'
Autor:
Cristina Maria Costantino, Achla Gupta, Alice W Yewdall, Benjamin M Dale, Lakshmi A Devi, Benjamin K Chen
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33961 (2012)
Agents that activate cannabinoid receptor pathways have been tested as treatments for cachexia, nausea or neuropathic pain in HIV-1/AIDS patients. The cannabinoid receptors (CB(1)R and CB(2)R) and the HIV-1 co-receptors, CCR5 and CXCR4, all signal vi
Externí odkaz:
https://doaj.org/article/872c63a286b44497a740ab34586757bd
Publikováno v:
The Journal of Immunology. 182:5654-5662
Fcγ receptor (FcγR)-mediated phagocytosis is known to require tyrosine kinases (TKs). We identified c-Cbl and Cbl-b as proteins that undergo tyrosine phosphorylation during phagocytosis. Cbl-deficient macrophages displayed enhanced FcγR-mediated s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::235573dbde9531ed58cd10b854fb1f70
https://doi.org/10.4049/jimmunol.0803942
https://doi.org/10.4049/jimmunol.0803942
Autor:
Steven Greenberg, Bitao Liang, Victor L. J. Tybulewicz, Marcella Flores, Nianyu Li, Edina Schweighoffer, Lucrezia Colonna, Raphael Clynes, Benjamin M. Dale, Craig Workman, Dario A. A. Vignali, Claude Chew, Janine Lee
Publikováno v:
The Journal of Immunology. 180:5916-5926
Lymphocyte activation gene-3 (LAG-3) is a CD4-related transmembrane protein expressed by regulatory T cells that binds MHC II on APCs. It is shown in this study that during Treg:DC interactions, LAG-3 engagement with MHC class II inhibits DC activati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2b1b29773de37f99e10b85bec8e7e47
https://doi.org/10.4049/jimmunol.180.9.5916
https://doi.org/10.4049/jimmunol.180.9.5916
Autor:
Steven Greenberg, Benjamin M. Dale
Publikováno v:
Phagocyte-Pathogen Interactions
Phagocytosis is a specialized endocytic response of eukaryotic cells to particulate stimuli, such as microbial pathogens. This response is utilized by myeloid cells of the immune system to aid in host defenses. FcγRI is expressed at especially high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b55e660abeee32197dc0400511f82758
https://doi.org/10.1128/9781555816650.ch4
https://doi.org/10.1128/9781555816650.ch4
Publikováno v:
The Journal of Experimental Medicine
The Src homology 2 domain-containing inositol 5'-phosphatase (SHIP) is recruited to immunoreceptor tyrosine-based inhibition motif (ITIM)-containing proteins, thereby suppressing phosphatidylinositol 3-kinase (PI 3-kinase)-dependent pathways. The rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceae702c5b899131587c38c23228dd00
http://europepmc.org/articles/PMC2195884
http://europepmc.org/articles/PMC2195884
Publikováno v:
Proceedings of the National Academy of Sciences. 97:680-685
Macrophages are specialized cells of the immune system that exhibit a prodigious capacity for phagocytosis. The ability of macrophages to internalize a substantial proportion of their plasma membrane during phagocytosis indicates that they possess a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26dada30587009a1c30a6744e0380fa9
https://doi.org/10.1073/pnas.97.2.680
https://doi.org/10.1073/pnas.97.2.680
Autor:
Benjamin K. Chen, Benjamin M. Dale, Gregory P. McNerney, Thomas R Huser, V. Monkemoller, W. Hubner
Publikováno v:
Scopus-Elsevier
The human immunodeficiency virus (HIV) is the agent of the global epidemic of the immune disease AIDS (acquired immunodeficiency syndrome). Therefore further investigations on the viral structure and molecular mechanisms are of particular importance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4d431861110ad6c7504f3f90ad5fa5a
https://doi.org/10.1109/cleoe-iqec.2013.6801497
https://doi.org/10.1109/cleoe-iqec.2013.6801497
Publikováno v:
Immunological reviews. 251(1)
Summary An elaborate network of cell–cell interactions in the immune system is essential for vertebrates to mount adaptive immune responses against invading pathogens. For lymphotropic viruses such as the human immunodeficiency virus type 1 (HIV-1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2e36da892f89d4fc506e2c526a099ef
https://pubmed.ncbi.nlm.nih.gov/23278744
https://pubmed.ncbi.nlm.nih.gov/23278744
Autor:
Alice W. Yewdall, Benjamin K. Chen, Lakshmi A. Devi, Cristina Maria Costantino, Benjamin M. Dale, Achla Gupta
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33961 (2012)
PLoS ONE
PLoS ONE
Agents that activate cannabinoid receptor pathways have been tested as treatments for cachexia, nausea or neuropathic pain in HIV-1/AIDS patients. The cannabinoid receptors (CB(1)R and CB(2)R) and the HIV-1 co-receptors, CCR5 and CXCR4, all signal vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d11e78b5374cd070ed1219ea23cbde76
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22448282/pdf/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22448282/pdf/?tool=EBI
Autor:
Claude Chew, Tetsuo Yamazaki, Daniel Traum, James E. Peacock, Steven Greenberg, Tomohiro Kurosaki, Benjamin M. Dale, Raphael Clynes, SungWon Song
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 187(2)
Macrophages are innate immune cells that play key roles in regulation of the immune response and in tissue injury and repair. In response to specific innate immune stimuli, macrophages may exhibit signs of endoplasmic reticulum (ER) stress and progre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa8207f6fcaf48582790a73050c40d91
https://pubmed.ncbi.nlm.nih.gov/21685326
https://pubmed.ncbi.nlm.nih.gov/21685326