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Autor:
Benjamin Livesey, Joseph Marsh
Publikováno v:
Livesey, B J & Marsh, J A 2022, ' Interpreting protein variant effects with computational predictors and deep mutational scanning ', Disease Models and Mechanisms, vol. 15, no. 6 . https://doi.org/10.1242/dmm.049510
Computational predictors of genetic variant effect have advanced rapidly in recent years. These programs provide clinical and research laboratories with a rapid and scalable method to assess the likely impacts of novel variants. However, it can be di