Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Benjamin Leadem"'
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114378- (2024)
Summary: The Myb proto-oncogene encodes the transcription factor c-MYB, which is critical for hematopoiesis. Distant enhancers of Myb form a hub of interactions with the Myb promoter. We identified a long non-coding RNA (Myrlin) originating from the
Externí odkaz:
https://doaj.org/article/512633a1430a496fac90bc4c3529afec
Autor:
Bart J. Currie, Asha Haslem, Talima Pearson, Heidie Hornstra, Benjamin Leadem, Mark Mayo, Daniel Gal, Linda Ward, Daniel Godoy, Brian G. Spratt, Paul Keim
Publikováno v:
Emerging Infectious Diseases, Vol 15, Iss 2, Pp 169-174 (2009)
Endemic melioidosis is caused by genetically diverse Burkholderia pseudomallei strains. However, clonal outbreaks (multiple cases caused by 1 strain) have occurred, such as from contaminated potable water. B. pseudomallei is designated a group B biot
Externí odkaz:
https://doaj.org/article/4be5d3d23dbf482f9e720babed07fc07
Autor:
Erin P Price, Heidie M Hornstra, Direk Limmathurotsakul, Tamara L Max, Derek S Sarovich, Amy J Vogler, Julia L Dale, Jennifer L Ginther, Benjamin Leadem, Rebecca E Colman, Jeffrey T Foster, Apichai Tuanyok, David M Wagner, Sharon J Peacock, Talima Pearson, Paul Keim
Publikováno v:
PLoS Pathogens, Vol 6, Iss 1, p e1000725 (2010)
Little is currently known about bacterial pathogen evolution and adaptation within the host during acute infection. Previous studies of Burkholderia pseudomallei, the etiologic agent of melioidosis, have shown that this opportunistic pathogen mutates
Externí odkaz:
https://doaj.org/article/c2136e5fe63e40d097e8953b27bba348
Autor:
Tommy K. Cheung, Catherine Wilson, Benjamin Leadem, Stephen B. Baylin, David Arnott, Ioannis Kagiampakis, Marie Classon, Hariharan Easwaran, Patrick Trojer
Publikováno v:
Cancer research. 78(5)
The H3K4 demethylase KDM5B is amplified and overexpressed in luminal breast cancer, suggesting it might constitute a potential cancer therapy target. Here, we characterize, in breast cancer cells, the molecular effects of a recently developed small-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e98436e22aae5b2a7bea441f3a9d4543
https://pubmed.ncbi.nlm.nih.gov/29282222
https://pubmed.ncbi.nlm.nih.gov/29282222
Autor:
Jeffrey T. Foster, Sharon J. Peacock, Talima Pearson, Apichai Tuanyok, David M. Wagner, Amy J. Vogler, Heidie Hornstra, Rebecca E. Colman, Erin P. Price, Derek S. Sarovich, Paul Keim, Benjamin Leadem, Jennifer L. Ginther, Tamara L. Max, Direk Limmathurotsakul, Julia Dale
Publikováno v:
PLoS Pathogens, Vol 6, Iss 1, p e1000725 (2010)
PLoS Pathogens
PLoS Pathogens
Little is currently known about bacterial pathogen evolution and adaptation within the host during acute infection. Previous studies of Burkholderia pseudomallei, the etiologic agent of melioidosis, have shown that this opportunistic pathogen mutates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deec7a9fac21e7c77a7499815808b782
https://ora.ox.ac.uk/objects/uuid:5aa6b5ea-3d20-4927-98d3-7046aaa2a66d
https://ora.ox.ac.uk/objects/uuid:5aa6b5ea-3d20-4927-98d3-7046aaa2a66d
Autor:
Paul Keim, Heidie Hornstra, James M. Schupp, Shalamar Georgia, Talima Pearson, Rasana W. Sermswan, Benjamin Leadem, Jana M. U'Ren
Publikováno v:
Applied and Environmental Microbiology. 73:6678-6681
Burkholderia pseudomallei soil isolates from northeast Thailand were genotyped using multiple-locus variable-number tandem repeat (VNTR) analysis (MLVA) and multilocus sequence typing (MLST). MLVA identified 19 genotypes within three clades, while ML
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb3186661b4641a111017dcb2cd2fb2c
https://doi.org/10.1128/aem.00986-07
https://doi.org/10.1128/aem.00986-07
Autor:
Talima Pearson, Jodie Low Choy, Amy J. Vogler, Mark Mayo, Shalamar Georgia, David M. Wagner, Peter G. Foster, Daniel Gal, Sergey Kachur, Gerard J. Allan, Paul Keim, Rebecca R Leadem Daugherty, Christine L Clark Friedman, James M. Schupp, Bart J. Currie, Jana M. U'Ren, Benjamin Leadem, Heidie Hornstra
Publikováno v:
Infection, Genetics and Evolution. 7:416-423
Molecular typing methods for Burkholderia pseudomallei have been successful at assigning isolates into epidemiologically related groups, but have not been able to detect differences and define evolutionary patterns within groups. Our variable number
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a975c6eee412f7aabc08637f0e9c474
https://doi.org/10.1016/j.meegid.2006.12.002
https://doi.org/10.1016/j.meegid.2006.12.002
Autor:
Hariharan Easwaran, Yi Cai, Benjamin Leadem, Eriko G. Clements, Leander Van Neste, Helai P. Mohammad, Stephen B. Baylin
Publikováno v:
Nucleic Acids Research
While DNA methyltransferase1 (DNMT1) is classically known for its functions as a maintenance methyltransferase enzyme, additional roles for DNMT1 in gene expression are not as clearly understood. Several groups have shown that deletion of the catalyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c8a3087e69391a04cb0175e1472c0a
https://pubmed.ncbi.nlm.nih.gov/22278882
https://pubmed.ncbi.nlm.nih.gov/22278882
Autor:
Zaining Wu, Mindy B. Glass, Siew Hoon Sim, Bart J. Currie, Paul Keim, Erin P. Price, Rajinder Kaul, Mark Mayo, Apichai Tuanyok, Gerard J. Allan, Ofori Pearson, Jeffrey T. Foster, Heidie Hornstra, Jay E. Gee, Benjamin Leadem, Thomas Brettin, Talima Pearson, Stephen M. Beckstrom-Sternberg, Richard T. Okinaka, Philip M. Giffard, Patrick Tan, James S. Beckstrom-Sternberg, Alex R. Hoffmaster, Richard A. Robison, Raymond K. Auerbach, David M. Wagner, Jean Chang
Publikováno v:
BMC Biology, Vol 7, Iss 1, p 78 (2009)
BMC Biology
BMC Biology
Background Phylogeographic reconstruction of some bacterial populations is hindered by low diversity coupled with high levels of lateral gene transfer. A comparison of recombination levels and diversity at seven housekeeping genes for eleven bacteria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e099568c6e1b6cac492251d9390c36e
http://www.biomedcentral.com/1741-7007/7/78
http://www.biomedcentral.com/1741-7007/7/78
Autor:
James S. Beckstrom-Sternberg, Apichai Tuanyok, Benjamin Leadem, Vanaporn Wuthiekanun, Paul Keim, David M. Wagner, Raymond K. Auerbach, Stephen M. Beckstrom-Sternberg, Sharon J. Peacock, William C. Nierman, Bart J. Currie, Thomas Brettin, Mark Mayo
Publikováno v:
BMC Genomics, Vol 9, Iss 1, p 566 (2008)
BMC Genomics
BMC Genomics
Background Burkholderia pseudomallei is the etiologic agent of melioidosis, a significant cause of morbidity and mortality where this infection is endemic. Genomic differences among strains of B. pseudomallei are predicted to be one of the major caus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a48078716b63494bb4507d4f23c64753
https://doi.org/10.1186/1471-2164-9-566
https://doi.org/10.1186/1471-2164-9-566