Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Benjamin L. Schlechter"'
Autor:
Justin Stebbing, Benjamin L Schlechter
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 5 (2024)
The CCR/L5 axis is known for its role in immune regulation in a variety of settings and has been shown to have dichotomous functions in cancer, influencing both tumor progression and immune responses. Battaglin et al investigated its role using genom
Externí odkaz:
https://doaj.org/article/f8c7e75c0f9741b9975d22caab997eef
Autor:
Benjamin L, Schlechter
Publikováno v:
Hematology/Oncology Clinics of North America. 36:521-537
Rectal cancer is an aggressive subtype of colon cancer with inferior outcomes in terms of disease-free and overall survival. Localized rectal cancer should be managed surgically. For stage II and III rectal cancer, neoadjuvant radiation, either as lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f93d8da549c187192b27caa5adf08d9
https://doi.org/10.1016/j.hoc.2022.03.002
https://doi.org/10.1016/j.hoc.2022.03.002
Autor:
Ecaterina Elena Dumbrava, Daniel Olson, Samuel Saibil, Brooke Pieke, Mridula A. George, Riemke Bouvier, Miriam Gavriliuc, Kelly Gruber, Kara Moss, Nathan Ternus, Maria Apostolopoulou, Deyaa Adib, Benjamin L. Schlechter
Publikováno v:
Cancer Research. 83:CT234-CT234
Background: Despite recent therapeutic developments for patients with advanced, metastatic, unresectable HER2+ solid tumors, significant unmet medical needs still exist, especially in tumors other than breast and gastric. The T cell antigen coupler (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e59b9d16f4d6cc534825bf373f62b6c2
https://doi.org/10.1158/1538-7445.am2023-ct234
https://doi.org/10.1158/1538-7445.am2023-ct234
Autor:
Benjamin G. Allar, Evangelos Messaris, Vitaliy Y. Poylin, Benjamin L. Schlechter, Thomas E. Cataldo
Publikováno v:
Medical Oncology. 39
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::430e22a7e3a7c5ef94f93eab3972808a
https://doi.org/10.1007/s12032-022-01660-9
https://doi.org/10.1007/s12032-022-01660-9
Autor:
Anthony B. El-Khoueiry, Marwan Fakih, Michael S. Gordon, Apostolia Maria Tsimberidou, Andrea J. Bullock, Breelyn A. Wilky, Jonathan C. Trent, Kim Allyson Margolin, Daruka Mahadevan, Ani Sarkis Balmanoukian, Rachel E. Sanborn, Gary K. Schwartz, Bruno Bockorny, Justin C Moser, Joseph Elan Grossman, Waldo Ignacio Ortuzar Feliu, Katherine Rosenthal, Steven O'Day, Heinz-Josef Lenz, Benjamin L. Schlechter
Publikováno v:
Journal of Clinical Oncology. 41:LBA8-LBA8
LBA8 Background: BOT promotes optimized T cell priming, activation and memory formation by strengthening antigen presenting cell/T cell co-engagement. As an Fc-enhanced next-generation anti–CTLA-4 antibody, BOT also promotes intratumoral regulatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a1593e4c8d6f518a9805c38850be755
https://doi.org/10.1200/jco.2023.41.4_suppl.lba8
https://doi.org/10.1200/jco.2023.41.4_suppl.lba8
Autor:
Benjamin L. Schlechter, Daniel Olson, Samuel Saibil, Mridula Annette George, Kelly Gruber, Riemke Bouvier, Brooke Pieke, Jill Geisburger, Kara M. Moss, Nathan Ternus, Deyaa R Adib, Ecaterina Elena Dumbrava
Publikováno v:
Journal of Clinical Oncology. 41:TPS816-TPS816
TPS816 Background: HER2 overexpression is well established as a therapeutic target in breast cancer and can be seen in a variety of gastrointestinal malignancies, notably in gastroesophageal cancer where positivity ranges from 4.4% to 53.4%. The rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::608e68fcf03fb798664eafdb92453d97
https://doi.org/10.1200/jco.2023.41.4_suppl.tps816
https://doi.org/10.1200/jco.2023.41.4_suppl.tps816
Publikováno v:
Journal of Onco-Nephrology. :239936932211503
Oxaliplatin, a platinum-based compound, is the standard cancer therapy for treatment of metastatic colorectal carcinoma and other gastrointestinal malignancies. Oxaliplatin-induced nephrotoxicities include acute kidney injury due to acute tubular inj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::360437dea96c3fd19fe951c0a937e010
https://doi.org/10.1177/23993693221150371
https://doi.org/10.1177/23993693221150371
Autor:
Brandon M, Huffman, Atrayee, Basu Mallick, Nora K, Horick, Andrea, Wang-Gillam, Peter Joel, Hosein, Michael A, Morse, Muhammad Shaalan, Beg, Janet E, Murphy, Sharon, Mavroukakis, Anjum, Zaki, Benjamin L, Schlechter, Hanna, Sanoff, Christopher, Manz, Brian M, Wolpin, Philip, Arlen, Jill, Lacy, James M, Cleary
Publikováno v:
JAMA Network Open. 6:e2249720
ImportanceTreatment options are limited for patients with advanced pancreatic ductal adenocarcinoma (PDAC) beyond first-line 5-fluorouracil, leucovorin, irinotecan, and oxaliplatin (FOLFIRINOX), with such individuals commonly being treated with gemci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e3a21732ce98e608c1b59db5d68d0c
https://doi.org/10.1001/jamanetworkopen.2022.49720
https://doi.org/10.1001/jamanetworkopen.2022.49720
Autor:
Harshabad Singh, Rachel B. Keller, Kevin S. Kapner, Julien Dilly, Srivatsan Raghavan, Chen Yuan, Eizabeth Cohen, Michael Tolstorukov, Emma Hill, Elizabeth Andrews, Lauren K. Brais, Annacarolina Da Silva, Kimberly Perez, Douglas A. Rubinson, Benjamin L. Schlechter, Michael H. Rosenthal, Jason L. Hornick, Valentina Nardi, Yvonne Li, Hersh Gupta, Andrew Cherniack, Mathew L. Meyerson, James M. Cleary, Jonathan A. Nowak, Brian M. Wolpin, Andrew A. Aguirre
Publikováno v:
Cancer Research. 82:A001-A001
Approximately 8-10% of pancreatic cancers do not harbor mutations in KRAS. Understanding the unique molecular and clinical features of this subset of pancreatic cancer (PC) is important to guide patient stratification for clinical trials of molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a219b475fc5e85321b9744bbf0c94808
https://doi.org/10.1158/1538-7445.panca22-a001
https://doi.org/10.1158/1538-7445.panca22-a001
Autor:
Benjamin L, Schlechter, Kimmie, Ng
Publikováno v:
Hematology/Oncology Clinics of North America. 36:xiii-xiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0183c0f4b4cfd956281c414c8b1d3968
https://doi.org/10.1016/j.hoc.2022.04.001
https://doi.org/10.1016/j.hoc.2022.04.001