Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Benjamin L. Farah"'
Autor:
Ruoyu Shi, Chik Hong Kuick, Angela Takano, Chuanhui Xu, Joe Poh Sheng Yeong, Benjamin L. Farah, Jian Yuan Goh, Kenneth Tou En Chang
Publikováno v:
Virchows Archiv. 480:383-391
The purpose of this study is to characterize the clinicopathological features of mass-forming immunoglobulin G4-related disease (IgG4-RD). A retrospective search for cases of mass-forming IgG4-RD diagnosed at Singapore General Hospital between 2008 a
Autor:
Benjamin L. Farah, Kesavan Sittampalam
Publikováno v:
Pathology. 53:654-658
Publikováno v:
Mol Genet Metab
The glycogen storage diseases are a group of inherited metabolic disorders that are characterized by specific enzymatic defects involving the synthesis or degradation of glycogen. Each disorder presents with a set of symptoms that are due to the unde
Autor:
Benjamin L Farah, Rohit A Sinha, Yajun Wu, Brijesh K Singh, Jin Zhou, Boon-Huat Bay, Paul M Yen
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98155 (2014)
Autophagy recently has been shown to be involved in normal hepatic function and in pathological conditions such as non-alcoholic fatty liver disease. Adrenergic signalling also is an important regulator of hepatic metabolism and function. However, cu
Externí odkaz:
https://doaj.org/article/bc3c012a92f1433ab6ac6332fd7c90f4
Autor:
S.H. Chew, Charissa Goh, C.H.R. Goh, R. Nadarajah, W.Y. Ho, S.L. Wong, Benjamin L. Farah, Y.K. Lim, T.H. Ho
Publikováno v:
Gynecologic Oncology Reports
Gynecologic Oncology Reports, Vol 32, Iss, Pp-(2020)
Gynecologic Oncology Reports, Vol 32, Iss, Pp-(2020)
Highlights • Dedifferentiated endometrioid adenocarcinoma is a rare aggressive subtype of endometrial cancer. • Patients tend to present at a later stage and have early recurrences. • Proportion of DEAC in endometrial cancer may affect outcome.
Autor:
Dustin J. Landau, Yajun Wu, Rohit A. Sinha, Benjamin L. Farah, Dwight D. Koeberl, Boon-Huat Bay, Alwin Hwai Liang Loh, Paul M. Yen
Publikováno v:
Molecular Genetics and Metabolism. 122:95-98
GSD Ia (von Gierke Disease, Glycogen Storage Disease Type Ia) is a devastating genetic disorder with long-term sequelae, such as non-alcoholic fatty liver disease and renal failure. Down-regulated autophagy is involved in the development of hepatic m
Publikováno v:
BMJ Case Rep
Mesenteric lymphangiomas are relatively rare, with clinical symptoms ranging from an asymptomatic presentation to an acute abdomen. The natural history and biological behaviour of this entity can range from slow indolent lesions to aggressive tumours
Autor:
Rohit A. Sinha, Madhulika Tripathi, Sujoy Ghosh, Jin Zhou, Kenji Ohba, Brijesh K. Singh, Sherwin Xie, Benjamin L. Farah, Anthony N. Hollenberg, Ronny Lesmana, Paul M. Yen
Publikováno v:
Autophagy
Lipotoxicity caused by saturated fatty acids (SFAs) induces tissue damage and inflammation in metabolic disorders. SCD1 (stearoyl-coenzyme A desaturase 1) converts SFAs to mono-unsaturated fatty acids (MUFAs) that are incorporated into triglycerides
Autor:
Boon-Huat Bay, Jessica R. Gooding, Rohit A. Sinha, Jin Zhou, Ronny Lesmana, Brijesh K. Singh, Kenji Ohba, Yajun Wu, Benjamin L. Farah, Paul M. Yen
Publikováno v:
Autophagy. 11:1341-1357
Currently, there is limited understanding about hormonal regulation of mitochondrial turnover. Thyroid hormone (T3) increases oxidative phosphorylation (OXPHOS), which generates reactive oxygen species (ROS) that damage mitochondria. However, the mec
Autor:
Andrea Lim, Masahiro Hirayama, Paul M. Yen, Rohit A. Sinha, Boon-Huat Bay, Brijesh K. Singh, Dustin J. Landau, Yajun Wu, Benjamin L. Farah, Dwight D. Koeberl
Publikováno v:
Scientific Reports
Glycogen storage disease type Ia (GSDIa, von Gierke disease) is the most common glycogen storage disorder. It is caused by the deficiency of glucose-6-phosphatase, an enzyme which catalyses the final step of gluconeogenesis and glycogenolysis. Clinic