Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Benjamin L. Edelman"'
Autor:
Joseph C. Cooley, Nomin Javkhlan, Jasmine A. Wilson, Daniel G. Foster, Benjamin L. Edelman, Luis A. Ortiz, David A. Schwartz, David W.H. Riches, Elizabeth F. Redente
Publikováno v:
JCI Insight, Vol 8, Iss 3 (2023)
Patients with progressive fibrosing interstitial lung diseases (PF-ILDs) carry a poor prognosis and have limited therapeutic options. A hallmark feature is fibroblast resistance to apoptosis, leading to their persistence, accumulation, and excessive
Externí odkaz:
https://doaj.org/article/96e206f68f934c4eb1c69abb77fc06c1
Autor:
Daniel G Foster, Nomin Javkhlan, Jasmine Wilson, Benjamin L. Edelman, David W. H. Riches, Elizabeth F. Redente
Publikováno v:
Journal of Clinical and Translational Science, Vol 7, Pp 133-134 (2023)
OBJECTIVES/GOALS: Silicosis is a highly fatal progressive fibrotic disease of the lungs characterized by accumulation and persistence of fibroblasts that excessively deposit Collagen1a1. We sought to eliminate Collagen1a1-expressing fibroblasts throu
Externí odkaz:
https://doaj.org/article/5fc1681d4c9945b19ea82670e716be67
Autor:
Zeev Dvir, Benjamin L. Edelman
Publikováno v:
Theory of Computing. 15:1-7
Matrix rigidity is a notion put forth by Valiant as a means for proving arithmetic circuit lower bounds. A matrix is rigid if it is far, in Hamming distance, from any low rank matrix. Despite decades of efforts, no explicit matrix rigid enough to car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2dba3773702a4b8b49677315228a793
https://doi.org/10.4086/toc.2019.v015a008
https://doi.org/10.4086/toc.2019.v015a008
Autor:
Max A. Seibold, Sangeeta Chakraborty, Bart P. Black, Satria Sajuthi, Benjamin L. Edelman, Elizabeth F. Redente, David W. H. Riches
Idiopathic pulmonary fibrosis (IPF) is a progressive, irreversible fibrotic disease of the distal lung alveoli that culminates in respiratory failure and reduced lifespan. Unlike normal lung repair in response to injury, IPF is associated with the ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c86dca8e843f42cf2fe2c1323c73bab7
https://doi.org/10.1101/2020.08.18.255869
https://doi.org/10.1101/2020.08.18.255869
Publikováno v:
EC
We initiate the study of the natural multiplayer generalization of the classic continuous Colonel Blotto game. The two-player Blotto game, introduced by Borel as a model of resource competition across $n$ simultaneous fronts, has been studied extensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc5a2f74c2ce30ddc398f1f6a9d38fd7
https://doi.org/10.1145/3391403.3399555
https://doi.org/10.1145/3391403.3399555
Autor:
David W. H. Riches, Andrew Thorburn, Alison Bamberg, Steve D. Groshong, Stijn De Langhe, Murry W. Wynes, Bart P. Black, Rubin M. Tuder, Luis A. Ortiz, Douglas Curran-Everett, Gregory P. Cosgrove, Elizabeth F. Redente, Rebecca C. Keith, Carlyne D. Cool, Benjamin L. Edelman
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 198:914-927
Idiopathic pulmonary fibrosis (IPF) is a progressive, fibrotic interstitial lung disease characterized by (myo)fibroblast accumulation and collagen deposition. Resistance to Fas-induced apoptosis is thought to facilitate (myo)fibroblast persistence i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cd75e2038aede8be5471a960260242c
https://doi.org/10.1164/rccm.201707-1497oc
https://doi.org/10.1164/rccm.201707-1497oc
Autor:
Elizabeth F. Redente, Karen E. Edeen, Amanda Mikels-Vigdal, Rachel L. Zemans, Douglas Curran-Everett, Karina A. Serban, Robert J. Mason, Kelly A. Correll, Benjamin L. Edelman
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
Epithelial-fibroblast interactions are thought to be very important in the adult lung in response to injury, but the specifics of these interactions are not well defined. We developed coculture systems to define the interactions of adult human alveol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd5d52e004a3e35aee8dfafdfe85c11d
https://pubmed.ncbi.nlm.nih.gov/31166130
https://pubmed.ncbi.nlm.nih.gov/31166130
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1809
The lung parenchyma is comprised of many cells including the structurally important stromal fibroblasts. Fibroblasts function to produce extracellular matrix and are important in the maintenance of alveolar epithelial cells. To understand the role of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0baf845dac42ede5f1ed37646e4ea889
https://pubmed.ncbi.nlm.nih.gov/29987782
https://pubmed.ncbi.nlm.nih.gov/29987782
Autor:
David A. Lynch, Ali N. Bahadur, Elizabeth F. Redente, Stephen M. Humphries, Benjamin L. Edelman, Martin A. Aguilar, Bart P. Black, David W. H. Riches, Lutz Wollin
Rheumatoid arthritis (RA)-associated interstitial lung disease (RA-ILD) develops in ~20% of patients with RA. SKG mice, which are genetically prone to development of autoimmune arthritis, develop a pulmonary interstitial pneumonia that resembles huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6289e875936b0dbbfa435b4778aaf74a
https://europepmc.org/articles/PMC6335004/
https://europepmc.org/articles/PMC6335004/
Publikováno v:
Methods in Molecular Biology ISBN: 9781493985692
The lung parenchyma is comprised of many cells including the structurally important stromal fibroblasts. Fibroblasts function to produce extracellular matrix and are important in the maintenance of alveolar epithelial cells. To understand the role of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4f58cf5f08c36423d87ba2c41674a50
https://doi.org/10.1007/978-1-4939-8570-8_5
https://doi.org/10.1007/978-1-4939-8570-8_5