Výsledky vyhledávání - "Benjamin L Duell"

Akademický článek

Human bladder uroepithelial cells synergize with monocytes to promote IL-10 synthesis and other cytokine responses to uropathogenic Escherichia coli.

Autor: Benjamin L Duell, Alison J Carey, Samantha J Dando, Mark A Schembri, Glen C Ulett

Publikováno v: PLoS ONE, Vol 8, Iss 10, p e78013 (2013)

Urinary tract infections are a major source of morbidity for women and the elderly, with Uropathogenic Escherichia coli (UPEC) being the most prevalent causative pathogen. Studies in recent years have defined a key anti-inflammatory role for Interleu

Externí odkaz: https://doaj.org/article/1b1cf9d8999d4bbbbd374983512e6ee7

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Akademický článek

Streptococcus agalactiae glyceraldehyde-3-phosphate dehydrogenase (GAPDH) elicits multiple cytokines from human cells and has a minor effect on bacterial persistence in the murine female reproductive tract

Autor: Matthew J. Sullivan, Kelvin G. K. Goh, Ruby Thapa, Debasish Chattopadhyay, Deepak S. Ipe, Benjamin L. Duell, Lahiru Katupitiya, Dean Gosling, Dhruba Acharya, Glen C. Ulett

Publikováno v: Virulence, Vol 12, Iss 1, Pp 3015-3027 (2021)

Streptococcus agalactiae glyceraldehyde 3-phosphate dehydrogenase (GAPDH), encoded by gapC, is a glycolytic enzyme that is associated with virulence and immune-mediated protection. However, the role of GAPDH in cellular cytokine responses to S. agala

Externí odkaz: https://doaj.org/article/75affdcbde0645aa8fa80d903f557a0a

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Akademický článek

Rapid Bladder Interleukin-10 Synthesis in Response to Uropathogenic Escherichia coli Is Part of a Defense Strategy Triggered by the Major Bacterial Flagellar Filament FliC and Contingent on TLR5

Autor: Dhruba Acharya, Matthew J. Sullivan, Benjamin L. Duell, Kelvin G. K. Goh, Lahiru Katupitiya, Dean Gosling, Michelle N. Chamoun, Asha Kakkanat, Debasish Chattopadhyay, Michael Crowley, David K. Crossman, Mark A. Schembri, Glen C. Ulett

Publikováno v: mSphere, Vol 4, Iss 6 (2019)

ABSTRACT Urinary tract infection (UTI) caused by uropathogenic Escherichia coli (UPEC) engages interleukin-10 (IL-10) as an early innate immune response to regulate inflammation and promote the control of bladder infection. However, the mechanism of

Externí odkaz: https://doaj.org/article/930a17e042a7487b9dc2d1c81b69a481

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Autor: Glen C. Ulett, Lahiru Katupitiya, Deepak S. Ipe, Dhruba Acharya, Matthew J. Sullivan, Debasish Chattopadhyay, Dean Gosling, Ruby Thapa, Benjamin L. Duell, Kelvin G. K. Goh

Publikováno v: Virulence, Vol 12, Iss 1, Pp 3015-3027 (2021)
Virulence
article-version (VoR) Version of Record

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc5f1a7c02dd8746e3e552e248b5a515

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Rapid bladder interleukin-10 synthesis in response to uropathogenic Escherichia coli is part of a defense strategy triggered by the major bacterial flagellar filament fliC and contingent on TLR5

Autor: Dean Gosling, Benjamin L. Duell, Michelle N. Chamoun, Michael J. Crowley, David K. Crossman, Lahiru Katupitiya, Glen C. Ulett, Debasish Chattopadhyay, Dhruba Acharya, Mark A. Schembri, Matthew J. Sullivan, Kelvin G. K. Goh, Asha Kakkanat

Publikováno v: mSphere, Vol 4, Iss 6, p e00545-19 (2019)
mSphere

Interleukin-10 is part of the immune response to urinary tract infection (UTI) due to E. coli, and it is important in the early control of infection in the bladder. Defining the mechanism of engagement of the immune system by the bacteria that enable

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bc00f29d9a77be4a9ff43391d9851e1
https://ueaeprints.uea.ac.uk/id/eprint/87241/

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Physical extraction and fast protein liquid chromatography for purifying flagella filament from uropathogenic Escherichia coli for immune assay

Autor: Dhruba Acharya, Matthew J. Sullivan, Benjamin L. Duell, Tanguy Eveno, Mark A. Schembri, Glen C. Ulett

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
Frontiers in Cellular and Infection Microbiology

Flagella are expressed on the surface of a wide range of bacteria, conferring motility and contributing to virulence and innate immune stimulation. Host-pathogen interaction studies of the roles of flagella in infection, including due to uropathogeni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::048854ed3823008df9ea6b701d012d8b
https://ueaeprints.uea.ac.uk/id/eprint/87242/

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Recent insights into microbial triggers of interleukin-10 production in the host and the impact on infectious disease pathogenesis: Table 1

Autor: Chee K. Tan, Alison J. Carey, Benjamin L. Duell, Fan Wu, Glen C. Ulett, Allan W. Cripps

Publikováno v: FEMS Immunology & Medical Microbiology. 64:295-313

Since its initial description as a Th2-cytokine antagonistic to interferon-alpha and granulocyte-macrophage colony-stimulating factor, many studies have shown various anti-inflammatory actions of interleukin-10 (IL-10), and its role in infection as a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d535cf2fa7e4e4b4d8db845ca36fd8c7
https://doi.org/10.1111/j.1574-695x.2012.00931.x

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The role of H4 flagella in Escherichia coli ST131 virulence

Autor: Asha Kakkanat, Benjamin L. Duell, Scott A. Beatson, Danilo Gomes Moriel, Minh-Duy Phan, Glen C. Ulett, Matthew J. Sweet, Mark A. Schembri, Alvin W. Lo, Kolja Schaale, Makrina Totsika

Publikováno v: Scientific Reports

Escherichia coli sequence type 131 (ST131) is a globally dominant multidrug resistant clone associated with urinary tract and bloodstream infections. Most ST131 strains exhibit resistance to multiple antibiotics and cause infections associated with l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf356130e908bf9abced643a026992c5
http://europepmc.org/articles/PMC4637896

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Uropathogenic Escherichia coli Engages CD14-Dependent Signaling to Enable Bladder-Macrophage-Dependent Control of Acute Urinary Tract Infection

Autor: Matthew J. Sweet, Andrew J. Brooks, Mark A. Schembri, Alison J. Carey, Debasish Chattopadhyay, Glen C. Ulett, Benjamin L. Duell, Chee K. Tan, Michael J. Crowley, Matthew J. Sullivan, David K. Crossman

Publikováno v: Journal of Infectious Diseases

Background - CD14, a coreceptor for several pattern recognition receptors and a widely used monocyte/macrophage marker, plays a key role in host responses to gram-negative bacteria. Despite the central role of CD14 in the inflammatory response to lip

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccec7be9bd59d43dd6879431e3e7d95f
https://pubmed.ncbi.nlm.nih.gov/26324782

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Innate transcriptional networks activated in bladder in response to uropathogenic Escherichia coli drive diverse biological pathways and rapid synthesis of IL-10 for defense against bacterial urinary tract infection

Autor: Alison J. Carey, Glen C. Ulett, Richard I. Webb, Andrew J. Brooks, Allan W. Cripps, Mark A. Schembri, Michael J. Crowley, Helen F. Irving-Rodgers, Petra Derrington, Makrina Totsika, Chee K. Tan, Benjamin L. Duell, Xiangqin Cui

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 188(2)

Early transcriptional activation events that occur in bladder immediately following bacterial urinary tract infection (UTI) are not well defined. In this study, we describe the whole bladder transcriptome of uropathogenic Escherichia coli (UPEC) cyst

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89eb4079f77cbca1ecfa6ff7665bb171
https://pubmed.ncbi.nlm.nih.gov/22184725

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