Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Benjamin L, Parker"'
Autor:
Hyun Soo Ko, Linda Denehy, Lara Edbrooke, Shadi Albarqouni, Ulrike Attenberger, Benjamin L. Parker, Andrew Cox, Brian Le, Louise Cheng
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 1, Pp 4-7 (2024)
Externí odkaz:
https://doaj.org/article/53ff6c9f8480410788b64932d5fa56db
Autor:
Mingqi Zhou, Ian Tamburini, Cassandra Van, Jeffrey Molendijk, Christy M Nguyen, Ivan Yao-Yi Chang, Casey Johnson, Leandro M Velez, Youngseo Cheon, Reichelle Yeo, Hosung Bae, Johnny Le, Natalie Larson, Ron Pulido, Carlos HV Nascimento-Filho, Cholsoon Jang, Ivan Marazzi, Jamie Justice, Nicholas Pannunzio, Andrea L Hevener, Lauren Sparks, Erin E Kershaw, Dequina Nicholas, Benjamin L Parker, Selma Masri, Marcus M Seldin
Publikováno v:
eLife, Vol 12 (2024)
Inter-organ communication is a vital process to maintain physiologic homeostasis, and its dysregulation contributes to many human diseases. Given that circulating bioactive factors are stable in serum, occur naturally, and are easily assayed from blo
Externí odkaz:
https://doaj.org/article/b0b0c3945a2343e1a77c073ec88b5282
Autor:
Jacob G. Smith, Kevin B. Koronowski, Thomas Mortimer, Tomoki Sato, Carolina M. Greco, Paul Petrus, Amandine Verlande, Siwei Chen, Muntaha Samad, Ekaterina Deyneka, Lavina Mathur, Ronnie Blazev, Jeffrey Molendijk, Arun Kumar, Oleg Deryagin, Mireia Vaca-Dempere, Valentina Sica, Peng Liu, Valerio Orlando, Benjamin L. Parker, Pierre Baldi, Patrick-Simon Welz, Cholsoon Jang, Selma Masri, Salvador Aznar Benitah, Pura Muñoz-Cánoves, Paolo Sassone-Corsi
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112588- (2023)
Summary: Physiology is regulated by interconnected cell and tissue circadian clocks. Disruption of the rhythms generated by the concerted activity of these clocks is associated with metabolic disease. Here we tested the interactions between clocks in
Externí odkaz:
https://doaj.org/article/da43be69311647c3a3d0a4fdfd5731ef
Autor:
Michael Papanicolaou, Amelia L. Parker, Michelle Yam, Elysse C. Filipe, Sunny Z. Wu, Jessica L. Chitty, Kaitlin Wyllie, Emmi Tran, Ellie Mok, Audrey Nadalini, Joanna N. Skhinas, Morghan C. Lucas, David Herrmann, Max Nobis, Brooke A. Pereira, Andrew M. K. Law, Lesley Castillo, Kendelle J. Murphy, Anaiis Zaratzian, Jordan F. Hastings, David R. Croucher, Elgene Lim, Brian G. Oliver, Fatima Valdes Mora, Benjamin L. Parker, David Gallego-Ortega, Alexander Swarbrick, Sandra O’Toole, Paul Timpson, Thomas R. Cox
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
The distribution and organisation of matrix molecules in the tumour stroma help shape solid tumour progression. Here they perform temporal proteomic profiling of the matrisome during breast cancer progression and show that collagen XII secreted from
Externí odkaz:
https://doaj.org/article/9576cecfa4d640e3988d0c14e35ac2b3
Autor:
Kamila A. Marzec, Samuel Rogers, Rachael McCloy, Benjamin L. Parker, David E. James, D. Neil Watkins, Andrew Burgess
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Microtubule-associated serine/threonine kinase-like (MASTL) has emerged as a critical regulator of mitosis and as a potential oncogene in a variety of cancer types. To date, Arpp-19/ENSA are the only known substrates of MASTL. However, with
Externí odkaz:
https://doaj.org/article/3331cc1a3f214642bc1ecc88d07abe93
Autor:
Magdalene K. Montgomery, Jacqueline Bayliss, Shuai Nie, William De Nardo, Stacey N. Keenan, Paula M. Miotto, Hamzeh Karimkhanloo, Cheng Huang, Ralf B. Schittenhelm, Anthony S. Don, Andrew Ryan, Nicholas A. Williamson, Geraldine J. Ooi, Wendy A. Brown, Paul R. Burton, Benjamin L. Parker, Matthew J. Watt
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Non-alcoholic steatohepatitis (NASH) and type 2 diabetes are closely linked, but the connecting pathophysiological mechanisms are incompletely understood. Here the authors identify arylsulfatase A as a NASH-induced hepatokine that inhibits hepatic ly
Externí odkaz:
https://doaj.org/article/0e3d36630f204b8aa3e526d0e0913eb1
Autor:
Jeffrey Molendijk, Ronnie Blazev, Richard J Mills, Yaan-Kit Ng, Kevin I Watt, Daryn Chau, Paul Gregorevic, Peter J Crouch, James BW Hilton, Leszek Lisowski, Peixiang Zhang, Karen Reue, Aldons J Lusis, James E Hudson, David E James, Marcus M Seldin, Benjamin L Parker
Publikováno v:
eLife, Vol 11 (2022)
Improving muscle function has great potential to improve the quality of life. To identify novel regulators of skeletal muscle metabolism and function, we performed a proteomic analysis of gastrocnemius muscle from 73 genetically distinct inbred mouse
Externí odkaz:
https://doaj.org/article/76f8d20a7ebb449dbd9f9358e1869662
Autor:
Di Xiao, Marissa Caldow, Hani Jieun Kim, Ronnie Blazev, Rene Koopman, Deborah Manandi, Benjamin L. Parker, Pengyi Yang
Publikováno v:
iScience, Vol 25, Iss 6, Pp 104489- (2022)
Summary: Myogenesis is governed by signaling networks that are tightly regulated in a time-dependent manner. Although different protein kinases have been identified, knowledge of the global signaling networks and their downstream substrates during my
Externí odkaz:
https://doaj.org/article/83a9d957718d45908a88326b811ef305
Autor:
Yue Xuan, Nicholas W. Bateman, Sebastien Gallien, Sandra Goetze, Yue Zhou, Pedro Navarro, Mo Hu, Niyati Parikh, Brian L. Hood, Kelly A. Conrads, Christina Loosse, Reta Birhanu Kitata, Sander R. Piersma, Davide Chiasserini, Hongwen Zhu, Guixue Hou, Muhammad Tahir, Andrew Macklin, Amanda Khoo, Xiuxuan Sun, Ben Crossett, Albert Sickmann, Yu-Ju Chen, Connie R. Jimenez, Hu Zhou, Siqi Liu, Martin R. Larsen, Thomas Kislinger, Zhinan Chen, Benjamin L. Parker, Stuart J. Cordwell, Bernd Wollscheid, Thomas P. Conrads
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Distributed multi-omic digitization of clinical specimen across multiple sites is a prerequisite for turning molecular precision medicine into reality. Here, the authors show that coordinated proteotype data acquisition is feasible using standardized
Externí odkaz:
https://doaj.org/article/081c4a0800724593aa4ff7b531e0218f
Autor:
Mengbo Li, Benjamin L. Parker, Evangeline Pearson, Benjamin Hunter, Jacob Cao, Yen Chin Koay, Oneka Guneratne, David E. James, Jean Yang, Sean Lal, John F. O’Sullivan
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Study of human heart failure is limited by access to human tissue. Here, the authors apply multi-omic screening in human ischaemic and dilated myocardial tissue and matched controls to determine molecular changes common and unique to each aetiology a
Externí odkaz:
https://doaj.org/article/dc50dd89da9c42378ed20e5b3c379c66