Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Benjamin Kumpfmueller"'
Autor:
Michael P Storm, Benjamin Kumpfmueller, Heather K Bone, Michael Buchholz, Yolanda Sanchez Ripoll, Julian B Chaudhuri, Hitoshi Niwa, David Tosh, Melanie J Welham
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e89821 (2014)
The Zscan4 family of genes, encoding SCAN-domain and zinc finger-containing proteins, has been implicated in the control of early mammalian embryogenesis as well as the regulation of pluripotency and maintenance of genome integrity in mouse embryonic
Externí odkaz:
https://doaj.org/article/f115cb6f69d24f3da5d9fd63436dc30a
Autor:
Yolanda Sanchez-Ripoll, Heather K Bone, Tom Owen, Ana M V Guedes, Elsa Abranches, Benjamin Kumpfmueller, Ruth V Spriggs, Domingos Henrique, Melanie J Welham
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60148 (2013)
Maintenance of embryonic stem cell (ESC) self-renewal and pluripotency are controlled by extrinsic factors, molecular signaling pathways and transcriptional regulators. While many of the key players have been studied in depth, how the molecular signa
Externí odkaz:
https://doaj.org/article/a9e71f4fc18749b099ef2b8d1780b2e0
Autor:
Belinda A.N. Thompson, Herbert Schulz, Benjamin Kumpfmueller, Melanie J. Welham, Jaak Vilo, Raivo Kolde, Oliver Hummel, Michael P. Storm
Publikováno v:
Stem Cells. 27:764-775
Phosphoinositide 3-kinase (PI3K)-dependent signaling has been implicated in the regulation of embryonic stem (ES) cell fate. To gain further insight into the mechanisms regulated by PI3Ks in murine ES cells, we have performed expression profiling usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5a2d6682223a27d4d890bf66458c5df
https://doi.org/10.1002/stem.3
https://doi.org/10.1002/stem.3
Autor:
Tina C. Stummann, Mateusz Wronski, Maurice Whelan, Benjamin Kumpfmueller, Tomasz Sobanski, Lars Hareng, Susanne Bremer
Publikováno v:
ASSAY and Drug Development Technologies. 6:375-385
Software, named Cardio Analyser, was developed for digital movie analysis of beating frequencies, drug-induced chronotropic effects, and quantification of beating areas of contracting cardiomyocyte cultures. A major novelty of the software is the int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9232de0c9d0862cc4526fd13248c0f6
https://doi.org/10.1089/adt.2008.129
https://doi.org/10.1089/adt.2008.129
Autor:
Silvia Saviozzi, Valentina Turinetto, Benjamin Kumpfmueller, Elisa Cibrario Rocchietti, Paola Circosta, Luca Orlando, Yolanda Sanchez-Ripoll, Kim Moorwood, Michael P. Storm, Alessandro Cignetti, Valentina Minieri, Lisa Accomasso, Claudia Giachino, Melanie J. Welham, Paola Porcedda
Publikováno v:
Stem cells (Dayton, Ohio). 30(7)
Phosphorylation of histone H2AX (γH2AX) is known to be the earliest indicator of DNA double-strand breaks. Recently, it has been shown that mouse embryonic stem cells (mESCs) have very high basal levels of γH2AX, even when they have not been expose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8dee437e638f13c30108906eead3e8e
https://pubmed.ncbi.nlm.nih.gov/22628289
https://pubmed.ncbi.nlm.nih.gov/22628289
Autor:
Benjamin Kumpfmueller, Yolanda Sanchez-Ripoll, Melanie J. Welham, Emmajayne Kingham, Michael P. Storm, Heather K. Bone
Publikováno v:
Welham, M J, Kingham, E, Sanchez Ripoll, Y, Kumpfmueller, B, Storm, M & Bone, H 2011, ' Controlling embryonic stem cell proliferation and pluripotency: the role of PI3K-and GSK-3-dependent signalling ', Biochemical Society Transactions, vol. 39, no. 2, pp. 674-678 . https://doi.org/10.1042/bst0390674
ESCs (embryonic stem cells) are derived from the inner cell mass of pre-implantation embryos and are pluripotent, meaning they can differentiate into all of the cells that make up the adult organism. This property of pluripotency makes ESCs attractiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1e90fdaec2e756713fada3cd6e40b41
https://pubmed.ncbi.nlm.nih.gov/21428960
https://pubmed.ncbi.nlm.nih.gov/21428960