Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Benjamin Klaffke"'
Autor:
Kendra J. Alfson, Yenny Goez-Gazi, Michal Gazi, Ying-Liang Chou, Nancy A. Niemuth, Marc E. Mattix, Hilary Staples, Benjamin Klaffke, Gloria F. Rodriguez, Priscilla Escareno, Carmen Bartley, Anysha Ticer, Elizabeth A. Clemmons, John W. Dutton III, Anthony Griffiths, Gabe T. Meister, Daniel C. Sanford, Chris M. Cirimotich, Ricardo Carrion
Publikováno v:
Vaccines, Vol 10, Iss 10, p 1723 (2022)
The primary objective of this study was to characterize the disease course in cynomolgus macaques exposed to Sudan virus (SUDV), to determine if infection in this species is an appropriate model for the evaluation of filovirus countermeasures under t
Externí odkaz:
https://doaj.org/article/2cc1aa54e7954ee49dfdea798a0267ee
Autor:
Kendra J. Alfson, Yenny Goez-Gazi, Michal Gazi, Ying-Liang Chou, Nancy A. Niemuth, Marc E. Mattix, Hilary M. Staples, Benjamin Klaffke, Gloria F. Rodriguez, Carmen Bartley, Anysha Ticer, Elizabeth A. Clemmons, John W. Dutton, Anthony Griffiths, Gabe T. Meister, Daniel C. Sanford, Chris M. Cirimotich, Ricardo Carrion
Publikováno v:
Vaccines, Vol 10, Iss 8, p 1314 (2022)
Marburg virus (MARV) is a filovirus that can infect humans and nonhuman primates (NHPs), causing severe disease and death. Of the filoviruses, Ebola virus (EBOV) has been the primary target for vaccine and therapeutic development. However, MARV has a
Externí odkaz:
https://doaj.org/article/21c882aa05dc43e9936872174f3053a7
Autor:
Kendra J. Alfson, Yenny Goez-Gazi, Michal Gazi, Hilary Staples, Marc Mattix, Anysha Ticer, Benjamin Klaffke, Kaylee Stanfield, Priscilla Escareno, Patrick Keiser, Anthony Griffiths, Ying-Liang Chou, Nancy Niemuth, Gabe T. Meister, Chris M. Cirimotich, Ricardo Carrion
Publikováno v:
Microorganisms, Vol 9, Iss 3, p 489 (2021)
Ebola virus (EBOV) is a negative-sense RNA virus that can infect humans and nonhuman primates with severe health consequences. Development of countermeasures requires a thorough understanding of the interaction between host and pathogen, and the cour
Externí odkaz:
https://doaj.org/article/ca56abe4ce0f4b8db6ddfb6339616cf3
Autor:
Min Ni, Anbo Zhou, Tammy Taylor, Mark G. Lewis, Anthony L. Cook, Maciel Porto, Olga Gonzalez, Neil Stahl, Adelekan Oyejide, Laurent Pessaint, Dharani Ajithdoss, John Dutton, Jack Greenhouse, Kendra J. Alfson, Edward J. Dick, Kathryn Lanza, Richard Copin, Christos A. Kyratsous, Bret J Musser, Kusha Mohammadi, Ricardo Carrion, Vaneesha Ali, Elizabeth Clemmons, Michal Gazi, George D. Yancopoulos, Nicole Negron, Hilary M. Staples, Hanne Leth Andersen, Gurinder S. Atwal, Alina Baum, Andrew J. Murphy, Renita Brown, Yenny Goez-Gazi, Yi Wei, Carmen Bartley, Benjamin Klaffke
Publikováno v:
Science
Science (New York, N.y.)
Science (New York, N.y.)
A beneficial cocktail Since the start of the coronavirus disease 2019 (COVID-19) pandemic, considerable effort has gone into generating and characterizing neutralizing antibodies that could be used as therapeutics. Studies in humanized mice and conva
Autor:
Patrick T Keiser, Anthony Griffiths, Marc Mattix, Chris M. Cirimotich, Kendra J. Alfson, Hilary M. Staples, Benjamin Klaffke, Kaylee Stanfield, Michal Gazi, Nancy A. Niemuth, Priscilla Escareno, Anysha Ticer, Yenny Goez-Gazi, Gabe T. Meister, Ricardo Carrion, Ying-Liang Chou
Publikováno v:
Microorganisms, Vol 9, Iss 489, p 489 (2021)
Microorganisms
Volume 9
Issue 3
Microorganisms
Volume 9
Issue 3
Ebola virus (EBOV) is a negative-sense RNA virus that can infect humans and nonhuman primates with severe health consequences. Development of countermeasures requires a thorough understanding of the interaction between host and pathogen, and the cour
Autor:
Justin Ferdin, Vida L. Hodara, Dhiraj Kumar Singh, Shalini Gautam, Shabaana A. Khader, Shannan Hall-Ursone, Shashank Ganatra, Yenny Goez-Gazi, Tae-Hyung Lee, Benjamin Klaffke, Riti Sharan, Elizabeth Clemmons, Cynthia Alvarez, Olga Gonzalez, Christopher H. Chen, Kathleen M. Brasky, Laura M. Parodi, Kendra J. Alfson, Rajesh Thippeshappa, Alyssa Schami, Joanne Turner, Richard Copin, Andra K. Voges, Angélica Olmo-Fontánez, Makedonka Mitreva, Michal Gazi, Amanda Mannino, Patrice A. Frost, Ruby Escobedo, Alyssa Blakley, Deepak Kaushal, Edward J. Dick, Julia M. Scordo, Dharani Ajithdoss, John Dutton, Journey Cole, Hilary M. Staples, Christos A. Kyratsous, Priscilla Escareno, Luis D. Giavedoni, Ricardo Carrion, Bruce A. Rosa, Maya Gough, Luis Martinez-Sobrido, Mushtaq Ahmed, Bindu Singh, Roy N. Platt, Cory R. A. Hallam, Ken Sayers, Jessica Callery, Jordi B. Torrelles, Adelekan Oyejide, Jean L. Patterson, Andreu G. Vilanova, Carmen Bartley, Tim J. Anderson, Xavier Alvarez, Anna Goodroe, Larry S. Schlesinger, Corinna N. Ross, Alina Baum, Ayan Chatterjee
Publikováno v:
Nature Microbiology
Non-human primate models will expedite therapeutics and vaccines for coronavirus disease 2019 (COVID-19) to clinical trials. Here, we compare acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in young and old rhesus macaque
REGN-COV2 antibody cocktail prevents and treats SARS-CoV-2 infection in rhesus macaques and hamsters
Autor:
Vaneesha Ali, Adelekan Oyejide, Min Ni, Maciel Porto, Hilary M. Staples, Hanne Leth Andersen, Elizabeth Clemmons, George D. Yancopoulos, Nicole Negron, Benjamin Klaffke, Alina Baum, Renita Brown, Richard Copin, Neil Stahl, Yenny Goez-Gazi, Kendra J. Alfson, Gurinder S. Atwal, Yi Wei, Jack Greenhouse, Laurent Pessaint, Michal Gazi, Andrew J. Murphy, Mark G. Lewis, Dharani Ajithdoss, John Dutton, Anthony L. Cook, Carmen Bartley, Christos A. Kyratsous, Kathryn Lanza, Ricardo Carrion, Olga Gonzales, Edward J. Dick, Anbo Zhou, Tammy Taylor
An urgent global quest for effective therapies to prevent and treat COVID-19 disease is ongoing. We previously described REGN-COV2, a cocktail of two potent neutralizing antibodies (REGN10987+REGN10933) targeting non-overlapping epitopes on the SARS-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80d7a5db0edff1dce694524bddc7a230
https://doi.org/10.1101/2020.08.02.233320
https://doi.org/10.1101/2020.08.02.233320
Autor:
Mushtaq Ahmed, Bindu Singh, Tim J. Anderson, Justin Ferdin, Shannan Hall-Ursone, Ruby Escabedo, Jean L. Patterson, Larry S. Schlesinger, Xavier Alvarez, Dhiraj Kumar Singh, Cory R. A. Hallam, Alina Baum, Michal Gazi, Bruce A. Rosa, Ken Sayers, Andra K. Voges, Corinna N. Ross, Jessica Callery, Amanda Mannino, Adelekan Oyejide, Carmen Bartley, Yenny Goez-Gazi, Ayan Chatterjee, Elizabeth Clemmons, Deepak Kaushal, Rajesh Thippeshappa, Cynthia Alvarez, Richard Copin, Tae-Hyung Lee, Edward J. Dick, Anna Goodroe, Hilary M. Staples, Christopher H. Chen, Julia M. Scordo, Journey Cole, Vida L. Hodara, Laura M. Parodi, Alyssa Blakely, Patrice A. Frost, Priscilla Escareno, Jordi B. Torrelles, Roy N. Platt, Riti Sharan, Benjamin Klaffke, Kendra J. Alfson, Olga Gonzalez, Shashank Ganatra, Makedonka Mitreva, Dharani Ajithdoss, John Dutton, Christos A. Kyratsous, Ricardo Carrion, Maya Gough, Luis Martinez-Sobrido, Shabaana A. Khader, Kathleen M. Brasky, Joanne Turner, Luis D. Giavedoni
SummaryThere are no known cures or vaccines for COVID-19, the defining pandemic of this era. Animal models are essential to fast track new interventions and nonhuman primate (NHP) models of other infectious diseases have proven extremely valuable. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8d413a8dcc19ee3e0c2687e656a5356
https://doi.org/10.1101/2020.06.05.136481
https://doi.org/10.1101/2020.06.05.136481