Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Benjamin K. Dickerman"'
Publikováno v:
F1000Research, Vol 2 (2014)
The dsRNA binding protein (dsRBP) PACT was first described as an activator of the dsRNA dependent protein kinase PKR in response to stress signals. Additionally, it has been identified as a component of the small RNA processing pathway. A role for PA
Externí odkaz:
https://doaj.org/article/913956b0ab264f99991607cfecff84f1
Publikováno v:
F1000Research, Vol 2 (2013)
The primary function of the dsRNA binding protein (dsRBP) PACT/RAX is to activate the dsRNA dependent protein kinase PKR in response to stress signals. Additionally, it has been identified as a component of the small RNA processing pathway. A role fo
Externí odkaz:
https://doaj.org/article/000cf0399f3749608f5713dbfbb39ab7
Autor:
Paul R. Gilson, Danushka S. Marapana, Andrew I. Webb, Benjamin K. Dickerman, Jarrod J. Sandow, Thomas Nebl, Tony Triglia, Alan F. Cowman, Justin A Boddey, Michał Pasternak, Laura F. Dagley, Brendan S. Crabb
Publikováno v:
Nature Microbiology. 3:1010-1022
Plasmodium falciparum exports hundreds of virulence proteins within infected erythrocytes, a process that requires cleavage of a pentameric motif called Plasmodium export element or vacuolar transport signal by the endoplasmic reticulum (ER)-resident
Autor:
Benjamin K Dickerman, Christine L White, Claire Chevalier, Valérie Nalesso, Cyril Charles, Sophie Fouchécourt, Florian Guillou, Laurent Viriot, Ganes C Sen, Yann Hérault
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28537 (2011)
Random chemical mutagenesis of the mouse genome can causally connect genes to specific phenotypes. Using this approach, reduced pinna (rep) or microtia, a defect in ear development, was mapped to a small region of mouse chromosome 2. Sequencing of th
Externí odkaz:
https://doaj.org/article/1e7874ab5f994f4db3d14f76f56a5652
Autor:
Sarah C. Charnaud, Paul A. Ramsland, Paul R. Gilson, Brendan S. Crabb, Benjamin K. Dickerman, Paul R Sanders
Publikováno v:
Journal of biochemistry. 165(3)
In order to facilitate a number of processes including nutrient acquisition and immune evasion, malaria parasites extensively remodel their host erythrocyte. This remodelling is to a large extent accomplished through protein export, a crucial process
Autor:
Scott A. Chisholm, Benjamin K. Dickerman, Paul R Sanders, Ming Kalanon, Thomas Nebl, Paul R. Gilson, Tania F. de Koning-Ward, Kathryn Matthews
Publikováno v:
The FEBS journal. 285(11)
The pathogenic nature of malaria infections is due in part to the export of hundreds of effector proteins that actively remodel the host erythrocyte. The Plasmodium translocon of exported proteins (PTEX) has been shown to facilitate the trafficking o
Autor:
Benjamin K. Dickerman, Anthony J. Devlin, Craig Freeman, Edwin A. Yates, Paul Horrocks, Lynsay C. Cooper, Michelle J. Boyle, James G. Beeson, Wengang Chai, Mark A. Skidmore
Publikováno v:
e00709-17
Despite recent successful control efforts, malaria remains a leading global health burden. Alarmingly, resistance to current antimalarials is increasing and the development of new drug families is needed to maintain malaria control. Current antimalar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93644fb73ee52b82eb28b51b487f5d07
https://eprints.keele.ac.uk/4069/1/AAC00709-17R1_Merged_PDF.pdf
https://eprints.keele.ac.uk/4069/1/AAC00709-17R1_Merged_PDF.pdf
Autor:
Simon A. Cobbold, Benjamin K. Dickerman, Catherine Q Nie, Brendan S. Crabb, Malcolm J. McConville, Paul R. Gilson, Brendan Elsworth
Publikováno v:
Scientific Reports
Plasmodium parasites are responsible for the devastating disease malaria that affects hundreds of millions of people each year. Blood stage parasites establish new permeability pathways (NPPs) in infected red blood cell membranes to facilitate the up
Autor:
Simon A. Cobbold, James I. MacRae, Brunda Nijagal, Benjamin K. Dickerman, Hwa H. Chua, Darren J. Creek, Malcolm J. McConville, Paul R. Gilson, Stuart A. Ralph
Publikováno v:
Antimicrobial agents and chemotherapy. 60(11)
High-throughput phenotypic screening of chemical libraries has resulted in the identification of thousands of compounds with potent antimalarial activity, although in most cases, the mechanism(s) of action of these compounds remains unknown. Here we
The chromosomally clustered interferon-induced with tetratricopeptide repeat motif (IFIT) gene family members share structural features at the gene and protein levels. Despite these similarities, different IFIT genes have distinct inducer- and cell t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33c74107bb48f1059b02b870563bc6bf
https://europepmc.org/articles/PMC4919440/
https://europepmc.org/articles/PMC4919440/