Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Benjamin K. Benton"'
Publikováno v:
Current Proteomics. 1:83-102
Autor:
Benjamin K. Benton, Alfred G. Gilman, John Manfredi, Roger K. Sunahara, Mark E. Hatley, Jun Xu
Publikováno v:
Journal of Biological Chemistry. 275:38626-38632
A genetic screen in Saccharomyces cerevisiae identified mutations in mammalian adenylyl cyclase that activate the enzyme in the absence of G(s)alpha. Thirteen of these mutant proteins were characterized biochemically in an assay system that depends o
Publikováno v:
Molecular and Cellular Biology. 17:5067-5076
Yeasts have three functionally redundant G1 cyclins required for cell cycle progression through G1. Mutations in GIN4 and CLA4 were isolated in a screen for mutants that are inviable with deletions in the G1 cyclins CLN1 and CLN2. cln1 cln2 cla4 and
Over-expression of S. cerevisiae G 1 cyclins restores the viability of alg 1 N-glycosylation mutants
Publikováno v:
Current Genetics. 29:106-113
In budding yeast, one of three G1 cyclins is required for progression though START, when cells commit to a further round of cell division. We have identified mutations in ALG1 (ERC14), a gene required for N-glycosylation, which are inviable in a cln1
Autor:
Suzanne Driscoll Plump, Benjamin K. Benton, Frederick R. Cross, William J. Lennarz, Jack Roos
Publikováno v:
Current Genetics. 29:106-113
In budding yeast, one of three G1 cyclins is required for progression though START, when cells commit to a further round of cell division. We have identified mutations inALG1 (ERC14), a gene required for N-glycosylation, which are inviable in acln1 c
Autor:
Aristidis Sachpatzidis, Benjamin K. Benton, John P. Manfredi, Hua Wang, Andrew Hamilton, Henrik G. Dohlman, Elias Lolis
Publikováno v:
The Journal of biological chemistry. 278(2)
The chemokine receptor CXCR4 is a co-receptor for T-tropic strains of HIV-1. A number of small molecule antagonists of CXCR4 are in development but all are likely to lead to adverse effects due to the physiological function of CXCR4. To prevent these
Publikováno v:
Genetics. 150(3)
The essential Sth1p is the protein most closely related to the conserved Snf2p/Swi2p in Saccharomyces cerevisiae. Sth1p purified from yeast has a DNA-stimulated ATPase activity required for its function in vivo. The finding that Sth1p is a component
Autor:
Christopher G.M. Wilson, Benjamin K. Benton, James M. Coull, Yumei Huang, Lawrence A. Haff, Julian F Bond, Andrew M. Stern, Richard F. Begley
Publikováno v:
Clinical Chemistry. 52:2147-2148
DNA-programmed chemistry (DPC) is a novel technology for synthesis of a wide variety of organic compounds at nanomolar concentrations under physiologic conditions (1). Annealing of small molecule-oligonucleotide precursors to DNA templates, each with
The CLN1, CLN2 and CLN3 gene family of G1-acting cyclin homologs of Saccharomyces cerevisiae is functionally redundant: any one of the three Cln proteins is sufficient for activation of Cdc28p protein kinase activity for cell cycle START. The START e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83c36918c383c659163b5508db2dfe84
https://europepmc.org/articles/PMC413792/
https://europepmc.org/articles/PMC413792/
Publikováno v:
Carcinogenesis. 14(6)
To determine if the tumor suppressor gene active in BHK hamster cells acts to maintain the normal phenotype by influencing oncogene transformation, careful, quantitative transfections with a variety of oncogenes were performed on four closely related