Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Benjamin J. Yungher"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/3332515a4d1b4249bc3fba882965296d
Autor:
Xueting Luo, Marcio Ribeiro, Eric R. Bray, Do-Hun Lee, Benjamin J. Yungher, Saloni T. Mehta, Kinjal A. Thakor, Francisca Diaz, Jae K. Lee, Carlos T. Moraes, John L. Bixby, Vance P. Lemmon, Kevin K. Park
Publikováno v:
Cell Reports, Vol 15, Iss 2, Pp 398-410 (2016)
Signal transducer and activator of transcription 3 (STAT3) is a transcription factor central to axon regrowth with an enigmatic ability to act in different subcellular regions independently of its transcriptional roles. However, its roles in mature C
Externí odkaz:
https://doaj.org/article/b2e6c11a964241089ed85d9b5858d3c9
Autor:
Melissa M. Holmes, Zhigang He, Xueting Luo, Skyler J. Mooney, Chen Wang, Kevin K. Park, Stephane Belin, Benjamin J. Yungher
Publikováno v:
Journal of Comparative Neurology. 525:380-388
In the adult mammalian central nervous system (CNS), axonal damage often triggers neuronal cell death and glial activation, with very limited spontaneous axon regeneration. In this study, we performed optic nerve injury in adult naked mole-rats, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2f23837730c11855b54f343b060c057
https://doi.org/10.1002/cne.24070
https://doi.org/10.1002/cne.24070
Autor:
Márcio Ribeiro, Samer Hattar, Gennady Dvoryanchikov, Konstantin Levay, Eric R. Bray, Kevin K. Park, Matt C. Danzi, Nirupa Chaudhari, Victoria S. Marks, Michael Randolph, Vance Lemmon, Ana C. Ayupe, Benjamin J. Yungher, Kinjal Thakor, Tiffany M. Schmidt
Publikováno v:
Neuron
Neuronal subtypes show diverse injury responses, but the molecular underpinnings remain elusive. Using transgenic mice that allow reliable visualization of axonal fate, we demonstrate that intrinsically photosensitive retinal ganglion cells (ipRGCs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47e94535a83b49a33b46ef8b1770ef10
https://pubmed.ncbi.nlm.nih.gov/31255486
https://pubmed.ncbi.nlm.nih.gov/31255486
Publikováno v:
Gene therapy
Lack of axon growth ability in the central nervous system poses a major barrier to achieving functional connectivity after injury. Thus, a non-transgenic regenerative approach to reinnervating targets has important implications in clinical and resear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3145664340f5423a206f34ceb1691a3
https://doi.org/10.1038/gt.2015.51
https://doi.org/10.1038/gt.2015.51
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Enhanced regeneration of retinal ganglion cell (RGC) axons can be achieved by modification of numerous neuronal-intrinsic factors. However, axon growth initiation and the pathfinding behavior of these axons after traumatic injury remain poorl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b0f4dd487a1be027a47f69f0dffc566
https://pubmed.ncbi.nlm.nih.gov/28324115
https://pubmed.ncbi.nlm.nih.gov/28324115
Autor:
Kevin K, Park, Xueting, Luo, Skyler J, Mooney, Benjamin J, Yungher, Stephane, Belin, Chen, Wang, Melissa M, Holmes, Zhigang, He
Publikováno v:
The Journal of comparative neurology. 525(2)
In the adult mammalian central nervous system (CNS), axonal damage often triggers neuronal cell death and glial activation, with very limited spontaneous axon regeneration. In this study, we performed optic nerve injury in adult naked mole-rats, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9a882d28b86725903dc2419e076db9c3
https://pubmed.ncbi.nlm.nih.gov/27350178
https://pubmed.ncbi.nlm.nih.gov/27350178
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 34(46)
Mammalian target of rapamycin (mTOR) functions as a master sensor of nutrients and energy, and controls protein translation and cell growth. Deletion of phosphatase and tensin homolog (PTEN) in adult CNS neurons promotes regeneration of injured axons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2daabf41e15db9aace1e026fa2bb5876
https://pubmed.ncbi.nlm.nih.gov/25392502
https://pubmed.ncbi.nlm.nih.gov/25392502
Publikováno v:
Methods in Molecular Biology ISBN: 9781493907762
Optic nerve crush injury, as a model to study central nervous system (CNS) injury, is widely used to assess potential therapeutic strategies, aimed at promoting axon regeneration and neuronal survival. Traditional methods to evaluate optic nerve rege
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e908e88ed8b33838668a1f86a728f6c4
https://doi.org/10.1007/978-1-4939-0777-9_17
https://doi.org/10.1007/978-1-4939-0777-9_17
