Evaluation of novel serological markers and autoantibodies in dogs with inflammatory bowel disease

Autor: Juan J. Estruch, Derren Barken, Nicole Bennett, Donald K. Krawiec, Gregory K. Ogilvie, Barbara E. Powers, Benjamin J. Polansky, Michael T. Sueda

Publikováno v: Journal of Veterinary Internal Medicine, Vol 34, Iss 3, Pp 1177-1186 (2020)

Abstract Background The use of serological markers to diagnose inflammatory bowel disease (IBD) in humans is well‐established. Because of the frequency of IBD in dogs and resources required for its diagnosis with current methods, new approaches are

Externí odkaz: https://doaj.org/article/f7aa33397cc046bf8981956d1ae1642b

Resolution of hyperinsulinemic hypoglycemia following partial pancreatectomy in a dog with nesidioblastosis

Autor: Stephen A. Martinez, Benjamin J. Polansky, Mark D. Chalkley

Publikováno v: Journal of the American Veterinary Medical Association. 253(7)

CASE DESCRIPTION A 6-year-old castrated male Australian Shepherd was evaluated because of a recent onset of persistent hypoglycemia. CLINICAL FINDINGS Physical examination results were generally unremarkable. No abnormalities were detected on thoraci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fa5bbd3480b1eaee0cf7d8411f63020
https://pubmed.ncbi.nlm.nih.gov/30211650

Discovery of functional elements in 12 Drosophila genomes using evolutionary signatures

Autor: Matthew W. Hahn, Angie S. Hinrichs, Benedict Paten, Colin N. Dewey, Stein Aerts, Jacques van Helden, Yongkyu Park, Madeline A. Crosby, Seung-Won Park, J. Graham Ruby, Alexander Stark, Sushmita Roy, Emily Hodges, David P. Bartel, Pouya Kheradpour, Michael B. Eisen, Gregory J. Hannon, Julius Brennecke, Michael P. Weir, Morgan L. Maeder, Lior Pachter, Benjamin J. Polansky, Jakob Skou Pedersen, Eric C. Lai, Bryanne E. Robson, Anat Caspi, Douglas Smith, David Haussler, W. James Kent, Andrew G. Clark, Susan E. Celniker, Deborah Eastman, Michael F. Lin, Mira V. Han, Ameya N. Deoras, Donald G. Gilbert, Thomas C. Kaufman, Joseph W. Carlson, Bassem A. Hassan, Matthew D. Rasmussen, Michael D. Rice, William M. Gelbart, Manolis Kellis, Leopold Parts

Publikováno v: Stark, A, Lin, M F, Kheradpour, P, Pedersen, J S, Parts, L, Carlson, J W, Crosby, M A, Rasmussen, M D, Roy, S, Deoras, A N, Ruby, J G, Brennecke, J, Hodges, E, Hinrichs, A S, Caspi, A, Paten, B, Park, S-W, Han, M V, Maeder, M L, Polansky, B J, Robson, B E, Aerts, S, van Helden, J, Hassan, B, Gilbert, D G, Eastman, D A, Rice, M, Weir, M, Hahn, M W, Park, Y, Dewey, C N, Pachter, L, Kent, W J, Haussler, D, Lai, E C, Bartel, D P, Hannon, G J, Kaufman, T C, Eisen, M B, Clark, A G, Smith, D, Celniker, S E, Gelbart, W M, Kellis, M & Harvard FlyBase curators 2007, ' Discovery of functional elements in 12 Drosophila genomes using evolutionary signatures ', Nature, vol. 450, no. 7167, pp. 219-32 . https://doi.org/10.1038/nature06340

Sequencing of multiple related species followed by comparative genomics analysis constitutes a powerful approach for the systematic understanding of any genome. Here, we use the genomes of 12 Drosophila species for the de novo discovery of functional

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0efd076672f0d607e82c41d9dae7d056
https://pure.au.dk/portal/da/publications/discovery-of-functional-elements-in-12-drosophila-genomes-using-evolutionary-signatures(07b43bc9-17c9-4e46-bc82-b0b5061edce3).html